trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride
![trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Structure](CAS/GIF/67198-13-4.gif)
- CAS No.
- 67198-13-4
- Chemical Name:
- trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride
- Synonyms
- u59900;U50,488;(+/-)-trans-U-50488;(+/-)-U-50488 hydroc;U-50488 mesylate (±)-;Top supplier U58800 U-50488 CAS NO.67198-13-4;2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetami de;N-Methyl-N-[2α-(1-pyrrolidinyl)cyclohexan-1β-yl]-3,4-dichlorophenylacetamide;N-Methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]-3,4-dichlorophenylacetamide;3,4-Dichloro-N-methyl-N-[2α-(pyrrolidin-1-yl)cyclohexan-1β-yl]benzeneacetamide
- CBNumber:
- CB71075363
- Molecular Formula:
- C19H26Cl2N2O
- Molecular Weight:
- 369.33
- MDL Number:
- MFCD03701498
- MOL File:
- 67198-13-4.mol
- TDS File:
- TDS
trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Properties
| Melting point | 204-208℃ |
|---|---|
| Boiling point | 496.565±45.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 1.238±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| RTECS | CY1484710 |
| storage temp. | Desiccate at RT |
| pka | 9.209±0.20(predicted) |
| FDA UNII | 39K8JHE8XN |
trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | U100235 | U50488 | 67198-13-4 | 1mg | $45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000222 | U-50488 95.00% | 67198-13-4 | 25MG | $970 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000222 | U-50488 95.00% | 67198-13-4 | 50MG | $1540 | 2021-12-16 | Buy |
trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Chemical Properties, Uses, Production
Uses
U 50488 is a selective κ-opioid agonist with analgesic, diuretic, and antitussive properties. κ-opioid agonists are useful compounds to elucidate the functions of κ-receptors in the central nervous system.
Definition
ChEBI: A monocarboxylic acid amide obtained by formal condensation between the carboxy group of 3,4-dichlorophenylacetic acid and the secondary amino group of (1R,2R)-N-methyl-2-(pyrrolidin-1-yl)cyclohexanamine
Biological Activity
Selective κ -opioid agonist. At higher concentrations blocks Na + channels. See separate isomers (trans-(-)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride and 0471 ).
