Boc-Glu-OMe
- CAS No.
- 72086-72-7
- Chemical Name:
- Boc-Glu-OMe
- Synonyms
- BOC-L-GLU-OME;Boc-L-Glutamic Acid 5-Methyl Ester;BOC-L-GLUTAMIC ACID METHYL ESTER;Boc-Glu-OMe;BOC-GLUTAMIC ACID-OME;BOC-GLU-OME USP/EP/BP;(Tert-Butoxy)Carbonyl Glu-OMe;Boc-L-glutamicacida-methylester;Boc-L-glutamic acid 1-methyl ester;Boc-L-glutamic acid α-methyl ester
- CBNumber:
- CB7119473
- Molecular Formula:
- C11H19NO6
- Molecular Weight:
- 261.27
- MDL Number:
- MFCD00076931
- MOL File:
- 72086-72-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 119-123℃ |
|---|---|
| Boiling point | 428.4±40.0 °C(Predicted) |
| Density | 1.182±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 4.48±0.10(Predicted) |
| color | Off-White to Light Yellow |
| InChI | InChI=1S/C11H19NO6/c1-11(2,3)18-10(16)12-7(9(15)17-4)5-6-8(13)14/h7H,5-6H2,1-4H3,(H,12,16)(H,13,14)/t7-/m0/s1 |
| InChIKey | ZAYAFKXUQMTLPL-ZETCQYMHSA-N |
| SMILES | C(OC)(=O)[C@H](CCC(O)=O)NC(OC(C)(C)C)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H302-H335-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P |
Boc-Glu-OMe price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-B656110-5G | N-Boc-L-glutamic Acid Alpha-Methyl Ester | 72086-72-7 | 5g | $205 | 2026-06-03 | Buy |
| TRC | TRC-B656110-50G | N-Boc-L-glutamic Acid Alpha-Methyl Ester | 72086-72-7 | 50g | $1092 | 2026-06-03 | Buy |
| TRC | TRC-B656110-100G | N-Boc-L-glutamic Acid Alpha-Methyl Ester | 72086-72-7 | 100g | $1757 | 2026-06-03 | Buy |
| Biosynth | FB42352 | Boc-glu-OMe | 72086-72-7 | 50g | $797.5 | 2026-06-04 | Buy |
| Biosynth | FB42352 | Boc-glu-OMe | 72086-72-7 | 100g | $1037 | 2026-06-04 | Buy |
Boc-Glu-OMe Chemical Properties, Uses, Production
Chemical Properties
White to off-white crystalline powder
Uses
N-Boc-L-glutamic Acid α-Methyl Ester is a glutamate derivative that undergoes vitamin K-dependent carboxylation in liver microsomes.
Synthesis
59279-58-2
72086-72-7
The general procedure for the synthesis of (S)-4-((tert-butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid from methyl (S)-5-benzyl-2-((tert-butoxycarbonyl)amino)pentanedioate was as follows: methyl (S)-5-benzyl-2-((tert-butoxycarbonyl)amino)pentanedioate (4.95 g, 14.09 mmol) was dissolved in 50 mL of a round bottom flask of methanol (20 mL) and 10% palladium/carbon catalyst was added under nitrogen protection. Subsequently, the reaction vessel was purged three times with nitrogen and hydrogen alternately. The reaction mixture was stirred for 6 hours under hydrogen atmosphere and atmospheric pressure. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the target compound (S)-4-((tert-butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid as a colorless gelatinous liquid (3.5 g, 96% yield). The specific optical rotation of the product [α]21D = +7 (c 0.1, CHCl3). Nuclear magnetic resonance hydrogen spectrum (1H NMR, CDCl3, 400 MHz) δ: 1.4 (s, 9H), 1.87-1.96 (m, 1H), 2.12-2.15 (m, 1H), 2.35-2.49 (m, 2H), 3.71 (s, 3H), 4.31-4.33 (d, 1H, J = 4.64 Hz), 5.24- 5.27 (d, 1H, J = 8.16 Hz), 10.19 (s, 1H). Nuclear magnetic resonance carbon spectrum (13C NMR, CDCl3, 100 MHz) δ: 27.5, 28.2, 30.0, 52.4, 52.8, 80.2, 155.5, 172.8, 177.7. infrared spectrum (IR, KBr) νmax: 3346, 2979, 1719, 1520, 1439, 1394, 1369. 1216, 1167, 1057, 1029, 879, 853, 816, 780, 596, 463 cm-1.
References
[1] Tetrahedron Letters, 1998, vol. 39, # 15, p. 2099 - 2102
[2] Organic and Biomolecular Chemistry, 2007, vol. 5, # 9, p. 1459 - 1465
[3] Chemical Communications, 2005, # 37, p. 4652 - 4654
[4] Tetrahedron Letters, 2014, vol. 55, # 14, p. 2274 - 2276
[5] Heterocycles, 2015, vol. 90, # 2, p. 1309 - 1316
Boc-Glu-OMe Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Mingma Technology Co., LTD | 17621758100 | sales@sunmatech.com | China | 140 | 58 |
| Sichuan Ampebiochem Co., Ltd. | 028-65294243 18682730901 | sales@ampebiochem.com | China | 1000 | 58 |
| Chengdu ruihede Medical Technology Co., Ltd | 17381862311; 17381862311 | sales2@ruihede.cn | China | 228 | 58 |
| Chongqing Hexu Technology Co., Ltd. | 19912419763 | 3319271734@qq.com | China | 20 | 58 |
| Hainan Bonsen New Technology Co., LTD | 17384938934 | 3984767441@qq.com | China | 25 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from Boc-Glu-OMe manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-10 | BOC-GLU-OME
72086-72-7
|
1KG | 98% | 100KG | Hainan Bonsen New Technology Co., LTD | ||
 |
2019-07-06 | BOC-GLU-OME
72086-72-7
|
$1.00 | 1KG | 99% | 20kg | Career Henan Chemical Co |
-
- BOC-GLU-OME
72086-72-7
- 98%
- Hainan Bonsen New Technology Co., LTD
-
- BOC-GLU-OME
72086-72-7
- $1.00
- 99%
- Career Henan Chemical Co
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