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4-BROMO-1-METHYL-1H-INDAZOLE

CAS No.
365427-30-1
Chemical Name:
4-BROMO-1-METHYL-1H-INDAZOLE
Synonyms
4-Bromo-1-methylindazole;1-Methyl-4-bromoindazole;4-BROMO-1-METHYL-1H-INDAZOLE;1H-Indazole, 4-bromo-1-methyl-
CBNumber:
CB71215949
Molecular Formula:
C8H7BrN2
Molecular Weight:
211.06
MDL Number:
MFCD09870042
MOL File:
365427-30-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:15
Product description Number Pack Size Price
4-Bromo-1-methyl-1H-indazole Asreported 266073 500mg $340
4-Bromo-1-methyl-1H-indazole Asreported 266073 1g $542
4-Bromo-1-methyl-1H-indazole Asreported 266073 2g $748
4-Bromo-1-methyl-1H-indazole Asreported 266073 5g $1034
4-Bromo-1-methyl-1H-indazole ≥95% (HPLC) ≥95%(HPLC) 232910 250mg $207

4-BROMO-1-METHYL-1H-INDAZOLE Properties

Boiling point 293.6±13.0 °C(Predicted)
Density 1.60±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka 0.26±0.30(Predicted)
form solid
color Off-white
InChI InChI=1S/C8H7BrN2/c1-11-8-4-2-3-7(9)6(8)5-10-11/h2-5H,1H3
InChIKey AQUSISHVASVOBL-UHFFFAOYSA-N
SMILES N1(C)C2=C(C(Br)=CC=C2)C=N1

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
Risk Statements  22
HS Code  2933998090

4-BROMO-1-METHYL-1H-INDAZOLE price More Price(76)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 266073 4-Bromo-1-methyl-1H-indazole Asreported 365427-30-1 500mg $340 2026-06-03 Buy
Usbiological 266073 4-Bromo-1-methyl-1H-indazole Asreported 365427-30-1 1g $542 2026-06-03 Buy
Usbiological 266073 4-Bromo-1-methyl-1H-indazole Asreported 365427-30-1 2g $748 2026-06-03 Buy
Usbiological 266073 4-Bromo-1-methyl-1H-indazole Asreported 365427-30-1 5g $1034 2026-06-03 Buy
Usbiological 232910 4-Bromo-1-methyl-1H-indazole ≥95% (HPLC) ≥95%(HPLC) 365427-30-1 250mg $207 2026-06-03 Buy
Product number Packaging Price Buy
266073 500mg $340 Buy
266073 1g $542 Buy
266073 2g $748 Buy
266073 5g $1034 Buy
232910 250mg $207 Buy

4-BROMO-1-METHYL-1H-INDAZOLE Chemical Properties,Uses,Production

Synthesis

Iodomethane

74-88-4

4-Bromo-1H-indazole

186407-74-9

4-BROMO-1-METHYL-1H-INDAZOLE

365427-30-1

4-BROMO-2-METHYL-2H-INDAZOLE

590417-93-9

GENERAL METHOD: 4-Bromo-1H-indazole (1 eq.) was mixed with potassium carbonate (3 eq.) in acetone (15-30 mL) and stirred at room temperature for 30 minutes. Subsequently, iodomethane (1.2-1.8 eq.) was slowly added to the reaction system and the reaction was heated under reflux conditions for 3-8 hours. After completion of the reaction, acetone was removed by evaporation under reduced pressure and the residue was dissolved in ethyl acetate (30 mL). The organic phase was washed with saturated saline (3 x 15 mL), dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel fast column chromatography (eluent: ethyl acetate/cyclohexane, 1:2 or dichloromethane) to afford the target products 4-bromo-1-methyl-1H-indazole and 4-bromo-2-methyl-2H-indazole, respectively.

References

[1] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 17, p. 5296 - 5304

74-88-4
186407-74-9
365427-30-1
590417-93-9
Synthesis of 4-BROMO-1-METHYL-1H-INDAZOLE from Iodomethane and 4-Bromo-1H-indazole

4-BROMO-1-METHYL-1H-INDAZOLE Suppliers

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4-BROMO-1-METHYL-1H-INDAZOLE Spectrum

4-BROMO-1-METHYL-1H-INDAZOLE 1-Methyl-4-bromoindazole 4-Bromo-1-methylindazole 1H-Indazole, 4-bromo-1-methyl- 365427-30-1 Building Blocks Indazole