ChemicalBook >> CAS DataBase List >>4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl-

4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl-

4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- structure

CAS No.: 1613481-52-9

Chemical Name:: 4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl-

Synonyms: Cholesterol 24-hydroxylase-IN-2;4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl-

CBNumber:: CB712188302

Molecular Formula:: C20H23FN4O

Molecular Weight:: 354.42

MDL Number:

MOL File:: 1613481-52-9.mol

Last updated:2025-04-17 18:22:24

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4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Properties

Boiling point	550.6±50.0 °C(Predicted)
Density	1.28±0.1 g/cm3(Predicted)
pka	3.39±0.27(Predicted)

4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Chemical Properties, Uses, Production

Uses

Cholesterol 24-hydroxylase-IN-2 is an inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), with the IC50 of 5.4 nM. Cholesterol 24-hydroxylase-IN-2 can be used in imaging of cholesterol 24-hydroxylase in mammals[1].

References

[1] Koike Tatsuki, et al. Preparation of arylpiperidines and arylpiperazines as radiolabeled compounds for use in imaging of cholesterol 24-hydroxylase. World Intellectual Property Organization, WO2015190613 A1 2015-12-17

4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Beckham Medical Technology Co., Ltd	13816613772	huahero21@sina.com	China	2994	55
Xilinglab Co., Ltd.	18884146872	bd@xilinglab.com	China	32	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
Shanghai Beckham Medical Technology Co., Ltd	55
Xilinglab Co., Ltd.	58
TargetMol Chemicals Inc.	58

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4-Piperidinecarboxamide, N-cyclopropyl-1-[4-(4-fluorophenyl)-5-pyrimidinyl]-N-methyl- Cholesterol 24-hydroxylase-IN-2 1613481-52-9