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ChemicalBook >> CAS DataBase List >>1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl-

1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl-

1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl- Structure
1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl- structure
CAS No.
2408639-81-4
Chemical Name:
1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl-
Synonyms
Topoisomerase I inhibitor 7;1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl-
CBNumber:
CB712663513
Molecular Formula:
C22H19N3O5
Molecular Weight:
405.4
MDL Number:
MOL File:
2408639-81-4.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl- Properties

Boiling point 737.2±60.0 °C(Predicted)
Density 1.561±0.06 g/cm3(Predicted)
pka 8.33±0.20(Predicted)

1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl- Chemical Properties, Uses, Production

Uses

Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor agent candidates among the heteroarene-fused anthraquinones[1].

References

[1] Tikhomirov AS, et al. Amides of pyrrole- and thiophene-fused anthraquinone derivatives: A role of the heterocyclic core in antitumor properties. Eur J Med Chem. 2020 Aug 1;199:112294. DOI:10.1016/j.ejmech.2020.112294

1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl- Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Topoisomerase I inhibitor 7 pictures 2026-04-20 Topoisomerase I inhibitor 7
2408639-81-4
 $1520.00-2500.00 10g TargetMol Chemicals Inc.

2408639-81-4 (1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl-) Related Search:

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1H-Naphth[2,3-f]indole-5,10-dione, 3-[[(3S)-3-amino-1-pyrrolidinyl]carbonyl]-4,11-dihydroxy-2-methyl- Topoisomerase I inhibitor 7 2408639-81-4