2-Pyrrolidinone,3-(hydroxymethyl)-1-methyl-(9CI)
- CAS No.
- 577780-05-3
- Chemical Name:
- 2-Pyrrolidinone,3-(hydroxymethyl)-1-methyl-(9CI)
- Synonyms
- 3-(HydroxyMethyl)-1-Methylpyrrolidin-2-one;3-(hydroxyMethyl)-1-Methyl-2-Pyrrolidinone;2-Pyrrolidinone, 3-(hydroxymethyl)-1-methyl-;2-Pyrrolidinone,3-(hydroxymethyl)-1-methyl-(9CI)
- CBNumber:
- CB71285223
- Molecular Formula:
- C6H11NO2
- Molecular Weight:
- 129.16
- MDL Number:
- MFCD18816870
- MOL File:
- 577780-05-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
2-Pyrrolidinone,3-(hydroxymethyl)-1-methyl-(9CI) price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 279658 | 3-(Hydroxymethyl)-1-methyl-2-pyrrolidinone Asreported | 577780-05-3 | 250mg | $1020 | 2026-06-03 | Buy |
| Usbiological | 279658 | 3-(Hydroxymethyl)-1-methyl-2-pyrrolidinone Asreported | 577780-05-3 | 500mg | $1303 | 2026-06-03 | Buy |
| Usbiological | 279658 | 3-(Hydroxymethyl)-1-methyl-2-pyrrolidinone Asreported | 577780-05-3 | 1g | $1770 | 2026-06-03 | Buy |
| Apolloscientific | OR470654 | 3-(Hydroxymethyl)-1-methyl-2-pyrrolidinone 95% | 577780-05-3 | 1g | $120 | 2026-06-04 | Buy |
| Matrix Scientific | 293965 | 3-(Hydroxymethyl)-1-methylpyrrolidin-2-one | 577780-05-3 | 250.00mg | $32 | 2026-05-19 | Buy |
2-Pyrrolidinone,3-(hydroxymethyl)-1-methyl-(9CI) Chemical Properties, Uses, Production
Synthesis
![2-Pyrrolidinone, 1-methyl-3-[(phenylmethoxy)methyl]-](/CAS/20210305/GIF/577780-04-2.gif)
577780-04-2
577780-05-3
3-[(Benzyloxy)methyl]-1-methylpyrrolidin-2-one (4.14 g, 18.88 mmol) was used as a raw material and dissolved in methanol (20 mL). Subsequently, 10% aqueous palladium carbon (1.04 g) was added and the reaction mixture was stirred at 0 °C. The reaction mixture was stirred at room temperature for 2 hours under hydrogen atmosphere. Upon completion of the reaction, the palladium carbon catalyst was removed by filtration and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography with the eluent ethyl acetate/methanol (10:1, v/v) to afford 1-methyl-3-(hydroxymethyl)-2-pyrrolidinone (1.55 g, 64% yield) as a colorless oil.1H-NMR (CDCl3) δ: 1.7-1.9 (1H, m), 2.05-2.25 (1H, m), 2.6 -2.8 (1H, m), 2.86 (3H, s), 3.25-3.45 (3H, m), 3.65-3.95 (2H, m).
References
[1] Patent: EP1479684, 2004, A1. Location in patent: Page 20
2-Pyrrolidinone,3-(hydroxymethyl)-1-methyl-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Kohn & Shawn Pharmatech Co.,Ltd | 0943-8293106 | sales@kyxpharma.com | China | 297 | 55 |
| Shanghai JingRon Chemical Technology Co., Ltd. | 021-60546673 13701861782; | kuanga111@sina.com | China | 882 | 58 |
| ShangHai Siyan Biological Technology Co., Ltd. | 021-50908862，442785678，326799392 18721037013 | siyansales@126.com | China | 9612 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| parabiochem | 025-83453382-8005 | sale@parabiochem.com | China | 9577 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Kangman Biological Technology Co., Ltd. | 18800375331 | kangmansales@163.com | China | 7559 | 55 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
