2-Pyridinesulfonamide,6-fluoro-(9CI)
- CAS No.
- 124433-70-1
- Chemical Name:
- 2-Pyridinesulfonamide,6-fluoro-(9CI)
- Synonyms
- 6-Fluoropyridine-2-sulfonamide;6-Fluoro-2-Pyridinesulfonamide;2-Pyridinesulfonamide,6-fluoro-;2-Pyridinesulfonamide,6-fluoro-(9CI)
- CBNumber:
- CB71289463
- Molecular Formula:
- C5H5FN2O2S
- Molecular Weight:
- 176.17
- MDL Number:
- MFCD18816593
- MOL File:
- 124433-70-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-Fluoropyridine-2-sulfonamide | B435570 | 5mg | $65 |
| 6-Fluoropyridine-2-sulfonamide | 0063AP | 100mg | $143 |
| 6-Fluoropyridine-2-sulfonamide | 0063AP | 250mg | $200 |
| 6-Fluoropyridine-2-sulfonamide 95% | A526293 | 1g | $230 |
| 6-Fluoropyridine-2-sulfonamide 95% | CM294876 | 1g | $262 |
| Boiling point | 374.8±52.0 °C(Predicted) |
|---|---|
| Density | 1.521±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 9.00±0.60(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C5H5FN2O2S/c6-4-2-1-3-5(8-4)11(7,9)10/h1-3H,(H2,7,9,10) |
| InChIKey | WYYFSNSPYJRQLU-UHFFFAOYSA-N |
| SMILES | C1(S(N)(=O)=O)=NC(F)=CC=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-Pyridinesulfonamide,6-fluoro-(9CI) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B435570 | 6-Fluoropyridine-2-sulfonamide | 124433-70-1 | 5mg | $65 | 2021-12-16 | Buy |
| AK Scientific | 0063AP | 6-Fluoropyridine-2-sulfonamide | 124433-70-1 | 100mg | $143 | 2021-12-16 | Buy |
| AK Scientific | 0063AP | 6-Fluoropyridine-2-sulfonamide | 124433-70-1 | 250mg | $200 | 2021-12-16 | Buy |
| Ambeed | A526293 | 6-Fluoropyridine-2-sulfonamide 95% | 124433-70-1 | 1g | $230 | 2021-12-16 | Buy |
| Chemenu | CM294876 | 6-Fluoropyridine-2-sulfonamide 95% | 124433-70-1 | 1g | $262 | 2021-12-16 | Buy |
2-Pyridinesulfonamide,6-fluoro-(9CI) Chemical Properties,Uses,Production
Synthesis
128583-07-3
124433-70-1
General procedure for the synthesis of 6-fluoro-2-pyridinesulfonamide from 6-fluoro-2-pyridinesulfonyl chloride: 6-fluoro-2-pyridinesulfonyl chloride (2.0875 g, 10.67 mmol) was dissolved in acetonitrile (50 mL) which was pre-cooled to 0 °C, and concentrated ammonia (70 mL, 539 mmol) was added slowly and dropwise. The reaction mixture was stirred at 0 °C for 30 min, then gradually warmed up to room temperature and continued stirring for 2 h. The reaction was completed by concentration reduction under reduced pressure. After the reaction was completed, some acetonitrile was removed by concentration under reduced pressure, and the residue was freeze-dried to obtain the target product, 6-fluoropyridine-2-sulfonamide, as a dark gray solid in 95% yield. The product was analyzed by LC/MS, ESI-MS m/z: 177.0 [M+H]+. 1H NMR (400 MHz, DMSO-d6) δ: 8.26 (q, J = 7.9 Hz, 1H), 7.88 (ddd, J = 7.5, 2.3, 0.6 Hz, 1H), 7.63 (s, 2H), 7.48 (ddd, J = 8.3, 2.4, 0.6 Hz). 2.4, 0.6 Hz, 1H).
References
[1] Patent: WO2018/42316, 2018, A1. Location in patent: Page/Page column 116; 117
[2] Patent: WO2011/94953, 2011, A1. Location in patent: Page/Page column 62-63
[3] Patent: WO2011/95576, 2011, A1. Location in patent: Page/Page column 62-63
[4] Patent: US2011/195979, 2011, A1. Location in patent: Page/Page column 34-35
[5] Patent: US2016/95858, 2016, A1. Location in patent: Paragraph 2135; 2136
2-Pyridinesulfonamide,6-fluoro-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
2-Pyridinesulfonamide,6-fluoro-(9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16516 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Chengda Pharmaceuticals Co., LTD. | 0573-84601188-809 18367305117; | scarlett.zhu@chengdapharm.com | China | 175 | 58 |
| ChangShu Haitian Fine Chemicals Co.,Ltd | 13913622609 | 974295387@qq.com | China | 192 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | chenyj@titansci.com | China | 14101 | 59 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 028-83379370 13880556291 | tcy@tcypharm.com | China | 7116 | 58 |
