2-Pyridinesulfonamide(6CI,7CI,9CI)
- CAS No.
- 63636-89-5
- Chemical Name:
- 2-Pyridinesulfonamide(6CI,7CI,9CI)
- Synonyms
- pyridine-2-sulfonamide;Pyridine -2-suflonly aMide;pyridine-2-sulfonic acid amide;2-Pyridinesulfonamide(6CI,7CI,9CI)
- CBNumber:
- CB41289189
- Molecular Formula:
- C5H6N2O2S
- Molecular Weight:
- 158.18
- MDL Number:
- MFCD09260336
- MOL File:
- 63636-89-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Pyridine-2-sulfonamide | NCA63689 | 1g | $206.25 |
| Pyridine-2-sulfonamide | NCA63689 | 5g | $618.75 |
| Pyridine-2-sulfonamide | NCA63689 | 10g | $893.8 |
| Pyridine-2-sulfonamide | NCA63689 | 25g | $1547 |
| 2-Pyridinesulfonamide 98% | AS12588 | 1g | $69 |
| More product size | |||
| Melting point | 140-141 °C(Solv: ethanol (64-17-5); water (7732-18-5)) |
|---|---|
| Boiling point | 357.7±34.0 °C(Predicted) |
| Density | 1.417±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 9.21±0.60(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C5H6N2O2S/c6-10(8,9)5-3-1-2-4-7-5/h1-4H,(H2,6,8,9) |
| InChIKey | DWJMBQYORXLGAE-UHFFFAOYSA-N |
| SMILES | C1(S(N)(=O)=O)=NC=CC=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362 |
2-Pyridinesulfonamide(6CI,7CI,9CI) price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | NCA63689 | Pyridine-2-sulfonamide | 63636-89-5 | 1g | $206.25 | 2026-06-04 | Buy |
| Biosynth | NCA63689 | Pyridine-2-sulfonamide | 63636-89-5 | 5g | $618.75 | 2026-06-04 | Buy |
| Biosynth | NCA63689 | Pyridine-2-sulfonamide | 63636-89-5 | 10g | $893.8 | 2026-06-04 | Buy |
| Biosynth | NCA63689 | Pyridine-2-sulfonamide | 63636-89-5 | 25g | $1547 | 2026-06-04 | Buy |
| Activate Scientific | AS12588 | 2-Pyridinesulfonamide 98% | 63636-89-5 | 1g | $69 | 2026-06-04 | Buy |
2-Pyridinesulfonamide(6CI,7CI,9CI) Chemical Properties,Uses,Production
Synthesis
2637-34-5
63636-89-5
General procedure for the synthesis of pyridine-2-sulfonamide from 2-pyridinethione: To a 1000 mL round-bottomed flask was added dichloromethane (200 mL) and 1 M aqueous hydrochloric acid solution (200 mL, 200 mmol, 5.0 equiv.), and the suspension was cooled to -5 to -10 °C using an ice-salt bath. To the well-stirred suspension was added 2-mercaptopyridine (4.45 g, 40 mmol), and the resulting yellow mixture was stirred for 10 minutes, followed by the dropwise addition of 6% sodium hypochlorite solution (208 mL, 132 mmol, 3.3 eq.) over 5 minutes. After the dropwise addition, the mixture was continued to be stirred at the same temperature for 10 min and subsequently transferred to a separatory funnel for separation. The separated organic layer was immediately added dropwise to a pre-cooled and stirred mixture of saturated ammonia methanol solution (80 mL) and dichloromethane (80 mL) at 0 °C. The aqueous layer in the partition funnel was washed twice with dichloromethane, and the organic layer was combined and added dropwise to the ammonia solution. The resulting white suspension was slowly warmed to room temperature and stirred for 2 hours. Subsequently, the solvent was removed by evaporation to give a white solid. The solid was dissolved in hot ethyl acetate (250 mL x 2) and filtered through filter paper to remove ammonium chloride. The filtrate was evaporated to give the crude product, which was finally purified by recrystallization from ethyl acetate and hexane to give pure pyridine-2-sulfonamide (4.15 g, 70% yield). The product was characterized by 1H NMR (500 MHz, DMSO-d6) and 13C NMR (125 MHz, DMSO-d6) and the data were consistent with the expected structure.
References
[1] Angewandte Chemie - International Edition, 2008, vol. 47, # 47, p. 9125 - 9129
[2] Synlett, 2018, vol. 29, # 9, p. 1232 - 1238
[3] Patent: WO2016/131098, 2016, A1. Location in patent: Page/Page column 122; 123
[4] Acta Poloniae Pharmaceutica, 1955, vol. 12, p. 5,8
[5] Chem.Abstr., 1957, p. 17911
2-Pyridinesulfonamide(6CI,7CI,9CI) Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8618071025641 | eric@witopchemical.com | China | 23506 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9897 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25333 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35405 | 58 |
View Lastest Price from 2-Pyridinesulfonamide(6CI,7CI,9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-07-12 | 2-Pyridinesulfonamide(6CI,7CI,9CI)
63636-89-5
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 2-Pyridinesulfonamide(6CI,7CI,9CI)
63636-89-5
- $1.00
- 99%
- Career Henan Chemical Co
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