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ChemicalBook >> CAS DataBase List >>Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]-

Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]-

Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]- Structure
Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]- structure
CAS No.
2414053-06-6
Chemical Name:
Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]-
Synonyms
AChE/HDAC-IN-1;Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]-
CBNumber:
CB712897932
Molecular Formula:
C26H27ClN4O3
Molecular Weight:
478.97
MDL Number:
MOL File:
2414053-06-6.mol
MSDS File:
SDS
Last updated:2026-04-21 10:31:43
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Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]- Properties

Density 1.340±0.06 g/cm3(Predicted)
pka 8+-.0.23(Predicted)

Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]- Chemical Properties, Uses, Production

Uses

COX-2-IN-23 (compound A10) is a potent both AChE and HDAC inhibitor with IC50 values of 0.12 and 0.23 nM. COX-2-IN-23 exhibits antioxidant activity and metal chelating properties. COX-2-IN-23 can be used in alzheimer's disease research[1].

IC 50

HDAC: 0.23 nM (IC50)

References

[1] Xu A, et al. Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation. Bioorg Chem. 2020 May;98:103721. DOI:10.1016/j.bioorg.2020.103721

Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]- Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AChE/HDAC-IN-1 pictures 2026-04-21 AChE/HDAC-IN-1
2414053-06-6
 $1520.00-2500.00 10g TargetMol Chemicals Inc.

2414053-06-6 (Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]-) Related Search:

Carbamazepine [4-[(Hydroxyamino)carbonyl]phenyl]carbamic acid [6-[(diethylamino)methyl]-2-naphthalenyl]methyl ester Tucidinostat (Chidamide) 4-Phenylbutyric acid Entinostat
(1S,4Z,7S,10S,11E,20R)-4-ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3,6,18,21-tetrazabicyclo[8.7.6]tricos-11-ene-2,5,8,19,22-pentone

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Benzamide, N-[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]-4-[(1E)-3-(hydroxyamino)-3-oxo-1-propen-1-yl]- AChE/HDAC-IN-1 2414053-06-6