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5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide

5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide structure

CAS No.: 1688684-07-2

Chemical Name:: 5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide

Synonyms: 5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide

CBNumber:: CB713525632

Molecular Formula:: C17H15ClFN5O3S2

Molecular Weight:: 455.92

MDL Number:

MOL File:: 1688684-07-2.mol

Last updated:2025-04-18 09:52:36

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5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide Properties

Density	1.502±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka	7.58±0.50(Predicted)

5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide Chemical Properties,Uses,Production

Uses

MPX-004 is a potent GluN2A antagonist. MPX-004 inhibits GluN2A-containing NMDA receptors expressed in HEK cells with an IC50 of 79 nM. MPX-004 has no inhibitory effect on GluN2B or GluN2D receptor-mediated responses. MPX-004 has the potential for neuropsychiatric and developmental disorders research[1].

IC 50

NMDA Receptor

References

[1] Robert A Volkmann, et al. MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit. PLoS One. 2016 Feb 1;11(2):e0148129. DOI:10.1371/journal.pone.0148129

5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd	025-58851090 17714375163	2881759498@qq.com	China	13011	58

Supplier	Advantage
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd	58

5-[[[(3-Chloro-4-fluorophenyl)sulfonyl]amino]methyl]-N-[(2-methyl-5-thiazolyl)methyl]-2-pyrazinecarboxamide 1688684-07-2 C17H15ClFN5O3S2