GB-6
- CAS No.
- 2413262-74-3
- Chemical Name:
- GB-6
- Synonyms
- GB-6
- CBNumber:
- CB714258397
- Molecular Formula:
- C32H45N11O8
- Molecular Weight:
- 711.77
- MDL Number:
- MOL File:
- 2413262-74-3.mol
- TDS File:
- TDS
GB-6 Chemical Properties,Uses,Production
Uses
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects[1].
IC 50
RDC Peptide
References
[1] Tu Y, et al. Novel GRPR-Targeting Peptide for Pancreatic Cancer Molecular Imaging in Orthotopic and Liver Metastasis Mouse Models. Anal Chem. 2023 Aug 1;95(30):11429-11439. DOI:10.1021/acs.analchem.3c01765
GB-6 Preparation Products And Raw materials
Raw materials
Preparation Products
GB-6 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanchang Tianzhen Biotechnology Co., Ltd | 13758194781 13173652190 | 522013271@qq.com | China | 2447 | 58 |
| Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd | 18020125070 | sales002@jszkhy.com | China | 2105 | 58 |
| Nanjing Typeptide Biotechnology Co.,Ltd. | 19961912513; 19941518170 | sales@typeptide.com | China | 4440 | 58 |
| ANHUI BYERSEN BIOTECH CO. LTD | +8617355064950 | amy@byersenchemical.com | China | 10000 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16505 | 58 |
