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3-((2,2,2- trifluoroethyl)thio)aniline

CAS No.
1445684-99-0
Chemical Name:
3-((2,2,2- trifluoroethyl)thio)aniline
Synonyms
Boc-D-His(Trt)-Aib-OH;Hydrolyzed silk protein;Boc-His(Trt)-Aib-D-Glu(OtBu)-Gly-OH;NA12878;MSI-78A;CarolGold;PBA-PEG-AC;WKPep Erasin;Palm-Glu-OtBu;Fmoc-D-Ala-Ala-OH
CBNumber:
CB71459710
Molecular Formula:
C8H8F3NS
Molecular Weight:
207.22
MDL Number:
MFCD21805732
MOL File:
1445684-99-0.mol
Last updated:2025-07-16 09:55:40

3-((2,2,2- trifluoroethyl)thio)aniline Properties

storage temp. 2-8°C, protect from light
Appearance Colorless to light yellow Liquid
InChI InChI=1S/C8H8F3NS/c9-8(10,11)5-13-7-3-1-2-6(12)4-7/h1-4H,5,12H2
InChIKey KMYQCBMXXMOPSD-UHFFFAOYSA-N
SMILES C1(N)=CC=CC(SCC(F)(F)F)=C1

3-((2,2,2- trifluoroethyl)thio)aniline price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA01K9KQ 3-[(2,2,2-Trifluoroethyl)sulfanyl]aniline 97% 1445684-99-0 250mg $234 2026-05-30 Buy
aablocks AA01K9KQ 3-[(2,2,2-Trifluoroethyl)sulfanyl]aniline 97% 1445684-99-0 1g $566 2026-05-30 Buy
aablocks AA01K9KQ 3-[(2,2,2-Trifluoroethyl)sulfanyl]aniline 97% 1445684-99-0 5g $1803 2026-05-30 Buy
ACHEMBLOCK H-8588 3-[(2,2,2-Trifluoroethyl)sulfanyl]aniline 97% 1445684-99-0 250MG $90 2026-05-27 Buy
ACHEMBLOCK H-8588 3-[(2,2,2-Trifluoroethyl)sulfanyl]aniline 97% 1445684-99-0 1G $230 2026-05-27 Buy
Product number Packaging Price Buy
AA01K9KQ 250mg $234 Buy
AA01K9KQ 1g $566 Buy
AA01K9KQ 5g $1803 Buy
H-8588 250MG $90 Buy
H-8588 1G $230 Buy

3-((2,2,2- trifluoroethyl)thio)aniline Chemical Properties, Uses, Production

Uses

3-((2,2,2-trifluoroethyl)thio)aniline can be used as an intermediate in pharmaceutical research.

Synthesis

To a solution of 3-aminobenzenethiol (4.43 g, 35.4 mmol) in THF (225 mL) was added sodium hydride (1.77 g, 44.3 mmol) at 0 °C and stirred for 30 min. Then, 2,2,2-trifluoroethyl 4- methylbenzenesulfonate (9.0 g, 35.4 mmol) was added and the reaction mixture was stirred for 18 h. The reaction mixture was quenched with water (20 mL) and extracted with EtOAc (2x50 mL). The combined organic extracts were washed with water, dried over Na2SO4, fdtered, and concentrated under reduced pressure. The crude residue was purified by flash chromatography through a Redi-Sep pre-packed silica gel column, eluting with a gradient of 5 % to 10 % EtOAc in hexanes, to give 3-((2,2,2- trifluoroethyl)thio)aniline (5 g, 68 % yield) as a pale brown oil.

3-((2,2,2- trifluoroethyl)thio)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 109)
Supplier Tel Email Country ProdList Advantage
Chengdu Pukang Biotechnology Co., Ltd 18217049878 cassie.gao@pu-kang.com China 480 58
Sichuan Yuehe Bio-Pharmaceutical Co.,Ltd 028-82729560 17365561851 tangzhichen@yuehepharm.com China 215 58
Taizhou GreenChem Pharmaceutical Co., Ltd. 0514-86654616 15366892466; greenchem@tzglmk.com China 498 56
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9778 55
Wuxi Asia Peptide Biotechnology Limited Company 0510-83583050 13771062561 willsun@peptide-search.com China 6713 58
XinYao(Shenzhen) Biological Technology Co., Ltd. 0755-89880280 3004662104@qq.com China 1826 58
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799 Eric@peptidego.com China 7872 58
PI & PI BIOTECH INC. +86-13602409664 +86-17788709170 Sales@pipitech.com China 2644 58
Shenzhen Readline Biotech CO., LTD. 0755-26659310 15915457431 linkunsheng@szreadline.com China 120 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58

View Latest Price from 3-((2,2,2- trifluoroethyl)thio)aniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
magnolol+honokiol pictures 2026-09-11 magnolol+honokiol
1kg 98% 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
Cefpodoxime Proxetil Impurity J pictures 2025-12-19 Cefpodoxime Proxetil Impurity J
10mg 90%+ 10g Guangzhou PI PI BIOTECH INC
4-Chluoro-2-bromotoluene pictures 2019-07-10 4-Chluoro-2-bromotoluene
1445684-99-0
$1.00 1ASSAYS 98% 1kg,2kg,100kg Career Henan Chemical Co

3-((2,2,2- trifluoroethyl)thio)aniline Spectrum

CarolGold Canthaxanthin Beadlet 10% CWS-S Canthaxanthin Beadlet 10% TAB CarolGold (Lutein) EMulsion CarolGold (Lutein) Powder Octadecane(OtBu)-Glu-OtBu Octadecane(OtBu)-Glu(AEEA-AEEA-NHS)-OtBu Boc-His(Trt)-Aib-Glu(OtBu)-Gly-NHS Palm-Glu-OtBu tBu-OOC-C18-CO-Glu-OtBu tBu-OOC-C14-CO-Glu(NHS)-OtBu Octadecane(OtBu)-D-Glu-OtBu Octadecane(OtBu)-D-Glu(ɑ-OtBu)-AEEA-AEEA-OH Octa(OtBu)-D-Glu-OtBu Boc-D-His(Trt)-Aib-D-Glu(OtBu)-Gly-OH Boc-D-His(Trt)-Aib-Glu(OtBu)-Gly-OH Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OR Fmoc-D-Ala-Ala-OH Fmoc-D-Lys(Palm-D-Glu-OtBu)-OH Fmoc-D-Lys(Palm-Glu-OtBu)-OH Fmoc-Lys(Palm-D-Glu-OtBu)-OH Octa(OtBu)-D-Glu(ɑ-OtBu)-AEEA-AEEA-OH 3,6-dibromo-9-(4-(naphthalen-2-yl)phenyl)-9H-carbazole BOC-(D)-HIS(TRT)-AIB CarolGold (Lutein) CarolGold (Lutein) Oil Suspension CarolZea (Zeaxanthin) CarolZea (Zeaxanthin) Oil Suspension Magnolol & Honokiol 3-[(2,2,2-TRIFLUOROETHYL)SULFANYL]ANILINE 1-(2-chlorophenyl)-ethane-1,2-bismethanesulfonate Endoxifen (E-isomer ) 4-Chluoro-2-bromotoluene 2-(4-Phenoxyphenyl)ethylboroni 3-(2-Trimethylsiloxyphenyl)-1- 3-Pentafluorophenyl-1-propylbo Tetrahydrothiophene-1,1-dioxid Trans-4-Bromo-beta-styrylboron Canthaxanthin Beadlet 10% Cefpodoxime Proxetil EP Impurity J Cefpodoxime Proxetil Impurity I Cefpodoxime Proxetil Impurity J 4-Fluoro-5-methyl-biphenyl-3-carbaldehyde Benzenamine, 3-[(2,2,2-trifluoroethyl)thio]- Nucleating agent NA-9930T Polypropylene Β-crystal nucleating agent TMB-5 TIANFU-CHEM CAS NO.000-00-0 4-Chluoro-2-bromotoluene Disodium 2‐fluoro‐2‐[1,1,2,3,3,3‐hexafluoro‐2‐(1,1,2,2‐tetrafluoro‐2‐sulfonatoethoxy)propoxy]acetate NA12878 PEI Prime Powder, Transfection Grade Linear Polyethylenimine Boldenone Propionate Raw Powder Phosphouous sul fochloride 4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)phenyl 4-methylbenzenesulfonate 1,5-Dibromo-2,4-bis(bromomethyl)-3-fluorobenzene Disposable injection pen Polyethylenimine Linear(PEI) WKPep Erasin PBA-PEG-AC