METHYL 3-ACETYL-4-HYDROXYBENZOATE
- CAS No.
- 57009-12-8
- Chemical Name:
- METHYL 3-ACETYL-4-HYDROXYBENZOATE
- Synonyms
- EOS-61538;Aspirin Impurity 13;Methyl-3-acetyl-4-hdyroxy benzoate;Methyl-3-acethyl-4-hdyroxy benzoate;Methanone,[6-(bromomethyl)phenyl]phenyl-;3-Acetyl-4-hydroxybenzoic acid methyl ester;Benzoic acid, 3-acetyl-4-hydroxy-, methyl ester
- CBNumber:
- CB71484820
- Molecular Formula:
- C10H10O4
- Molecular Weight:
- 194.18
- MDL Number:
- MFCD06797942
- MOL File:
- 57009-12-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Acetyl-4-hydroxybenzoic acid methyl ester | FA137928 | 2g | $150 |
| 3-Acetyl-4-hydroxybenzoic acid methyl ester | FA137928 | 1g | $150 |
| 3-Acetyl-4-hydroxybenzoic acid methyl ester | FA137928 | 0.5g | $150 |
| 3-Acetyl-4-hydroxybenzoic acid methyl ester | FA137928 | 0.25g | $150 |
| 3-Acetyl-4-hydroxybenzoic acid methyl ester | FA137928 | 5g | $249.85 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H335-H318-H315 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310-P264-P270-P301+P312-P330-P501 |
METHYL 3-ACETYL-4-HYDROXYBENZOATE price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FA137928 | 3-Acetyl-4-hydroxybenzoic acid methyl ester | 57009-12-8 | 2g | $150 | 2026-06-04 | Buy |
| Biosynth | FA137928 | 3-Acetyl-4-hydroxybenzoic acid methyl ester | 57009-12-8 | 1g | $150 | 2026-06-04 | Buy |
| Biosynth | FA137928 | 3-Acetyl-4-hydroxybenzoic acid methyl ester | 57009-12-8 | 0.5g | $150 | 2026-06-04 | Buy |
| Biosynth | FA137928 | 3-Acetyl-4-hydroxybenzoic acid methyl ester | 57009-12-8 | 0.25g | $150 | 2026-06-04 | Buy |
| Biosynth | FA137928 | 3-Acetyl-4-hydroxybenzoic acid methyl ester | 57009-12-8 | 5g | $249.85 | 2026-06-04 | Buy |
METHYL 3-ACETYL-4-HYDROXYBENZOATE Chemical Properties,Uses,Production
Uses
Methyl 3-Acetyl-4-hydroxybenzoate is used to prepare and study structure-activity relationships of 2-(1-adamantyl)-4-(thio)chromenone-6-carboxylic acids as potent reversible inhibitors of human steroid sulfatase.
Synthesis
111-34-2
29415-97-2
57009-12-8
Step 2: To a degassed ethanol (3 L) solution of methyl 3-bromo-4-hydroxybenzoate (350 g, 1514.87 mmol) under nitrogen protection were sequentially added triethylamine (0.528 L, 3787.17 mmol), 1-(vinyloxy)butane (0.588 L, 4544.60 mmol), 1,1 '-bis(diphenylphosphino) ferrocene (33.1 g, 60.6 mmol) and diacetoxypalladium (8.50 g, 37.9 mmol). The reaction mixture was stirred at 70 °C overnight. After completion of the reaction, the mixture was cooled to room temperature, filtered and the filtrate was concentrated. The resulting solid was dissolved with dichloromethane (2 L), followed by the slow addition of 4 N hydrochloric acid (1.14 L, 4544 mmol) under stirring. After continued stirring for 2 h, the organic phase was separated, dried with anhydrous magnesium sulfate, filtered and concentrated to give the crude product. The crude product was dissolved in ether (5 L), stirred for 2 h, filtered, and the filtrate was concentrated to dryness to give methyl 3-acetyl-4-hydroxybenzoate (240 g, 82% yield) as a beige powder. Mass spectral data: [MH]- 193.
References
[1] Patent: US2011/98271, 2011, A1. Location in patent: Page/Page column 39
[2] Patent: WO2011/51704, 2011, A1. Location in patent: Page/Page column 99
[3] Patent: WO2012/140419, 2012, A1. Location in patent: Page/Page column 87
[4] Patent: US2012/264731, 2012, A1. Location in patent: Page/Page column 34; 35
[5] Journal of Medicinal Chemistry, 2015, vol. 58, # 2, p. 943 - 962
METHYL 3-ACETYL-4-HYDROXYBENZOATE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
| Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. | +86-029-86185165 +86-18629664246 | guoyuan@eastchinapharm.com | China | 1612 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +86-13336024896 | CB@aromsyn.com | China | 19176 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19621 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| Compound Net Biotechnology Inc. | 15266686121 | sales@compound-net.com | China | 2913 | 58 |
| HANGZHOU HAILAN CHEMICAL CO.,LTD. | +86-57156122185 +86-15967590394 | sales@hailan-chem.com | China | 2998 | 58 |
57009-12-8(METHYL 3-ACETYL-4-HYDROXYBENZOATE)Related Search:
1of3
