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NSC-124854

NSC-124854 structure

CAS No.: 1033942-30-1

Chemical Name:: NSC-124854

Synonyms: NSC-124854;2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-5-O-phosphonopentofuranosyl)-5,6-dihydro-6-iodo-

CBNumber:: CB714907439

Molecular Formula:: C9H15IN3O7P

Molecular Weight:: 435.11

MDL Number:

MOL File:: 1033942-30-1.mol

MSDS File:: SDS

Last updated:2025-04-18 09:52:37

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NSC-124854 Properties

Boiling point	669.594±65.00 °C(Press: 760.00 Torr)(predicted)
Density	2.555±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	1.856±0.10(predicted)

NSC-124854 Chemical Properties, Uses, Production

Uses

NSC-124854 is a DNA polymerase β (Pol-β) inhibitor with an IC50 of 5.3 μM. NSC-124854 has antitumor activity[1].

References

[1] Jaiswal AS, et al. DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer. PLoS One. 2011 Feb 2;6(2):e16691. DOI:10.1371/journal.pone.0016691

NSC-124854 Preparation Products And Raw materials

Raw materials

Preparation Products

NSC-124854 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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NSC-124854 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-5-O-phosphonopentofuranosyl)-5,6-dihydro-6-iodo- 1033942-30-1