2-Chloro-3-pyridineacetic acid
- CAS No.
- 61494-55-1
- Chemical Name:
- 2-Chloro-3-pyridineacetic acid
- Synonyms
- 2-(2-chloropyridin-3-yl)acetic acid;2-(2-chloropyridin-3-yl)acetic;2-Chloro-3-pyridineacetic acid;2-Chloropyridine-3-acetic acid;(2-Chloro-3-pyridyl)acetic Acid;3-Pyridineacetic acid, 2-chloro-;2-(2-chloro-3-pyridyl)acetic acid;2-(2-Chloropyridin-3-yl)aceticaci;2-CHLORO-PYRIDINE-3-YL-ACETIC ACID;3-(Carboxymethyl)-2-chloropyridine
- CBNumber:
- CB71501293
- Molecular Formula:
- C7H6ClNO2
- Molecular Weight:
- 171.58
- MDL Number:
- MFCD09757512
- MOL File:
- 61494-55-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(2-Chloropyridin-3-yl)aceticAcid | B405235 | 100mg | $60 |
| 2-Chloro-3-pyridineaceticacid | Y5005 | 250mg | $162 |
| (2-Chloropyridin-3-yl)acetic acid 95.0% | 4H21-5-0A | 1g | $375 |
| 2-CHLORO-3-PYRIDINEACETIC ACID 95.00% | HCH0357716 | 5MG | $503.31 |
| 2-(2-chloropyridin-3-yl)aceticacid 97% | CM108316 | 10g | $688 |
| More product size | |||
| Melting point | 203-204 °C(Solv: benzene (71-43-2)) |
|---|---|
| Boiling point | 336.6±27.0 °C(Predicted) |
| Density | 1.405±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 3.79±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C7H6ClNO2/c8-7-5(4-6(10)11)2-1-3-9-7/h1-3H,4H2,(H,10,11) |
| InChIKey | NOASBJYTBZMVKT-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=CC=C1CC(O)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| HS Code | 2933399990 |
2-Chloro-3-pyridineacetic acid price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B405235 | 2-(2-Chloropyridin-3-yl)aceticAcid | 61494-55-1 | 100mg | $60 | 2021-12-16 | Buy |
| AK Scientific | Y5005 | 2-Chloro-3-pyridineaceticacid | 61494-55-1 | 250mg | $162 | 2021-12-16 | Buy |
| SynQuest Laboratories | 4H21-5-0A | (2-Chloropyridin-3-yl)acetic acid 95.0% | 61494-55-1 | 1g | $375 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0357716 | 2-CHLORO-3-PYRIDINEACETIC ACID 95.00% | 61494-55-1 | 5MG | $503.31 | 2021-12-16 | Buy |
| Chemenu | CM108316 | 2-(2-chloropyridin-3-yl)aceticacid 97% | 61494-55-1 | 10g | $688 | 2021-12-16 | Buy |
2-Chloro-3-pyridineacetic acid Chemical Properties,Uses,Production
Physical Form
Solid
Uses
2-(2-Chloropyridin-3-yl)acetic Acid can be prepared to use as RORγ agonists for the treatment of cancer.
Synthesis
101012-32-2
61494-55-1
General procedure for the synthesis of 2-chloropyridine-3-acetic acid from (2-chloropyridin-3-yl)acetonitrile: 15% w/w NaOH solution (15 mL) was added to (2-chloropyridin-3-yl)acetonitrile (0.932 g, 6.1 mmol). The reaction mixture was heated to reflux for 35 min and subsequently cooled to room temperature. The mixture was further cooled to 0 °C and acidified to pH 1 with concentrated hydrochloric acid (about 5 mL of hydrochloric acid was required). The resulting suspension was allowed to stand in an ice bath for 1 hour. The precipitate was collected by filtration and washed with cold isopropanol (3 x 15 mL) to afford 2-chloropyridine-3-acetic acid (1.05 g, 100% yield) as an off-white solid.1H NMR (400 MHz, d6-DMSO) δ 12.63 (s, 1H), 8.32 (dd, J = 4.8, 1.9 Hz, 1H), 7.86 (dd, J = 7.5, 1.9 Hz, 1H). 1.9 Hz, 1H), 7.41 (dd, J = 7.5, 4.8 Hz, 1H), 3.75 (s, 2H).LCMS Method C: Retention time 4.06 min; m/z 172 [M+H]+.
References
[1] Patent: WO2012/110773, 2012, A1. Location in patent: Page/Page column 138; 139
[2] Patent: WO2014/27199, 2014, A1. Location in patent: Page/Page column 141
[3] Patent: WO2009/13462, 2009, A1. Location in patent: Page/Page column 26
[4] Patent: WO2009/93008, 2009, A1. Location in patent: Page/Page column 25-26
[5] Patent: WO2009/153554, 2009, A1. Location in patent: Page/Page column 36
2-Chloro-3-pyridineacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 | info@pbpharm.com | CHINA | 498 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 | |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18895 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
View Lastest Price from 2-Chloro-3-pyridineacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-17 | 2-CHLORO-3-PYRIDINEACETIC ACID
61494-55-1
|
US $2.00-6.00 / kg | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2025-11-18 | 2-Chloro-3-pyridineacetic acid
61494-55-1
|
US $1.10 / g | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-01-15 | 2-Chloro-3-pyridineacetic acid
61494-55-1
|
US $1.00 / g | 1g | 99% | 10000KGS | Career Henan Chemical Co |
-
- 2-CHLORO-3-PYRIDINEACETIC ACID
61494-55-1
- US $2.00-6.00 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 2-Chloro-3-pyridineacetic acid
61494-55-1
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2-Chloro-3-pyridineacetic acid
61494-55-1
- US $1.00 / g
- 99%
- Career Henan Chemical Co
