derquantel
- CAS No.
- 187865-22-1
- Chemical Name:
- derquantel
- Synonyms
- derquantel;Unii-0L0ugk6oox;2-Deoxoparaherquamide;Derquantel in methanol;2-DeoxoparaherquaMide, 2-DeoxoparaherquaMide A, 2-DesoxoparaherquaMide A, PF 00520904, PNU 141962;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizin]-10'-one, 2',3',8'a,9,9',10-hexahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
- CBNumber:
- CB71518503
- Molecular Formula:
- C28H37N3O4
- Molecular Weight:
- 479.61
- MDL Number:
- MFCD13195549
- MOL File:
- 187865-22-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 641.3±55.0 °C(Predicted) |
|---|---|
| Density | 1.34 |
| storage temp. | Store at -20°C |
| solubility | DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble |
| form | A solid |
| pka | 15.18±0.60(Predicted) |
| color | White to off-white |
| JECFA Number | 75 |
| FDA UNII | 0L0UGK6OOX |
derquantel price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19441 | Derquantel ≥98% | 187865-22-1 | 5mg | $354 | 2026-04-30 | Buy |
| Cayman Chemical | 19441 | Derquantel ≥98% | 187865-22-1 | 25mg | $1408 | 2026-04-30 | Buy |
| ChemScene | CS-0089578 | Derquantel 98.4% | 187865-22-1 | 5mg | $1062 | 2026-06-04 | Buy |
| ApexBio Technology | C4619 | Derquantel | 187865-22-1 | 5mg | $461 | 2026-05-06 | Buy |
| ApexBio Technology | C4619 | Derquantel | 187865-22-1 | 25mg | $1841 | 2026-05-06 | Buy |
derquantel Chemical Properties, Uses, Production
Description
Derquantel is an anthelmintic spiroindole that acts as a nicotinic acetylcholine receptor antagonist, causing flaccid paralysis and expulsion of nematodes. A combination of derquantel and the macrocyclic lactone, abamectin , has been found to have synergistic anthelmintic effects against gastrointestinal nematode parasites in sheep.
Uses
Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection, reduction, N-deprotection and a final reduction. Derquantel isa potent nematocide and was the first paraherquamide to be successfully commercialised in combination with avermectin. Derquantel, like other paraherquamides, induces a flaccid paralysis in nematodes thought to be due to inhibition of nicotinic acetylcholine receptors acting as an antagonist of acetylcholine.
Definition
ChEBI: Derquantel is an azaspiro compound.
References
[1] M. ABONGWA. Curiouser and Curiouser: The Macrocyclic Lactone, Abamectin, Is also a Potent Inhibitor of Pyrantel/Tribendimidine Nicotinic Acetylcholine Receptors of Gastro-Intestinal Worms[J]. PLoS ONE, 2016, 11 1. DOI: 10.1371/journal.pone.0146854
derquantel Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4578 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4372 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20000 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15030 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8857 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
View Latest Price from derquantel manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Derquantel
187865-22-1
|
$4685.00 | 10g | TargetMol Chemicals Inc. |
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- Derquantel
187865-22-1
- $4685.00
- TargetMol Chemicals Inc.
