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ChemicalBook >> CAS DataBase List >>1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)

1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)

1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) Structure
1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) structure
CAS No.
Chemical Name:
1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)
Synonyms
1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)
CBNumber:
CB715519703
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2025-08-21 11:10:20
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1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) Properties

solubility Methanol: Soluble

1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 39227 1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) ≥95% 1mg $107 2026-04-30 Buy
Cayman Chemical 39227 1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) ≥95% 5mg $481 2026-04-30 Buy
Product number Packaging Price Buy
39227 1mg $107 Buy
39227 5mg $481 Buy

1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) Chemical Properties, Uses, Production

Description

1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (1-arachidoyl LPA) is an agonist of lysophosphatidic acid receptor 1 (LPA1) and a glycerophospholipid containing arachidic acid (Item Nos. 9000339 | 21906) at the sn-1 position.1 It induces calcium mobilization in primary human lung fibroblasts (EC50 = 3.6 µM), which endogenously express LPA1 but not LPA2-LPA6. 1-Arachidoyl LPA (2.5 µM) also binds to the ligand-binding domain of peroxisome proliferator-activated receptor γ (PPARγ) in a cell-free assay.2 It has been found in human urine.3WARNING This product is not for human or veterinary use.

References

[1] AFRAH SATTIKAR  Elizabeth M R  Mark R Dowling. Endogenous lysophosphatidic acid (LPA1) receptor agonists demonstrate ligand bias between calcium and ERK signalling pathways in human lung fibroblasts[J]. British Journal of Pharmacology, 2016, 174 3: 227-237. DOI: 10.1111/bph.13671
[2] TAMOTSU TSUKAHARA. Different residues mediate recognition of 1-O-oleyllysophosphatidic acid and rosiglitazone in the ligand binding domain of peroxisome proliferator-activated receptor gamma.[J]. The Journal of Biological Chemistry, 2006, 281 6: 3398-3407. DOI: 10.1074/jbc.m510843200
[3] SANGSOO LIM. Computational approach to structural identification of phospholipids using raw mass spectra from nanoflow liquid chromatography–electrospray ionization–tandem mass spectrometry[J]. Journal of Mass Spectrometry, 2012, 47 8: 1004-1014. DOI: 10.1002/jms.3033

1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) Preparation Products And Raw materials

Raw materials

Preparation Products

1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
Cayman Chemical Company -- sales@caymanchem.com China 6808 58
Neobioscience Co., Ltd. -- info@neobioscience.com CHINA 6192 58
Supplier Advantage
Cayman Chemical Company 58
Neobioscience Co., Ltd. 58

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1-Arachidoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)