3-Bromoimidazo[1,2-a]pyrimidine
- CAS No.
- 6840-45-5
- Chemical Name:
- 3-Bromoimidazo[1,2-a]pyrimidine
- Synonyms
- -Bromoimidazo[1,2-a]pyrimidine;3-BROMOIMIDAZO[1,2-A]PYRIMIDINE;Imidazo[1,2-a]pyrimidine, 3-bromo-;3-BROMOIMIDAZOL-(1,2-A)-PYRIMIDINE;3-Bromoimidazo[1,2-a]pyrimidine 98%;3-Bromoimidazo[1,2-a]pyrimidine ISO 9001:2015 REACH
- CBNumber:
- CB7175802
- Molecular Formula:
- C6H4BrN3
- Molecular Weight:
- 198.02
- MDL Number:
- MFCD06200962
- MOL File:
- 6840-45-5.mol
- MSDS File:
- SDS
| Melting point | 158-160 |
|---|---|
| Density | 1.89±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 2.55±0.30(Predicted) |
| color | Light brown |
| InChI | InChI=1S/C6H4BrN3/c7-5-4-9-6-8-2-1-3-10(5)6/h1-4H |
| InChIKey | GNHZXUKWLSWKHB-UHFFFAOYSA-N |
| SMILES | C12=NC=C(Br)N1C=CC=N2 |
| CAS DataBase Reference | 6840-45-5(CAS DataBase Reference) |
3-Bromoimidazo[1,2-a]pyrimidine price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 54635 | 3-BROMOIMIDAZO[1,2-A]PYRIMIDINE 97% | 6840-45-5 | 5G | $79 | 2026-04-30 | Buy |
| Activate Scientific | AS22654 | 3-Bromoimidazo[1,2-a]pyrimidine 98% | 6840-45-5 | 1g | $20 | 2026-06-04 | Buy |
| Activate Scientific | AS22654 | 3-Bromoimidazo[1,2-a]pyrimidine 98% | 6840-45-5 | 5g | $62 | 2026-06-04 | Buy |
| Activate Scientific | AS22654 | 3-Bromoimidazo[1,2-a]pyrimidine 98% | 6840-45-5 | 25g | $255 | 2026-06-04 | Buy |
| Activate Scientific | AS22654 | 3-Bromoimidazo[1,2-a]pyrimidine 98% | 6840-45-5 | 100g | $835 | 2026-06-04 | Buy |
3-Bromoimidazo[1,2-a]pyrimidine Chemical Properties, Uses, Production
Uses
3-Bromoimidozolo[1,2-a]pyrimidine can be used to prepare HPK1 inhibitors.
Synthesis
274-95-3
6840-45-5
Imidazo[1,2-a]pyrimidine (4 g) and sodium acetate (4.3 g) were dissolved in methanol (40 ml) in a 100 ml three-necked round-bottomed flask, followed by cooling the reaction mixture to -10°C. Bromine (5.38 g) was added slowly and dropwise with stirring. Upon completion of the reaction, 1M aqueous sodium sulfide (40 ml) was added to quench the reaction and the mixture was subsequently concentrated under reduced pressure to remove the solvent. Liquid-liquid extraction was carried out via ethyl acetate and water to separate the by-products, and finally the crude product was purified by column chromatography using dichloromethane and methanol as eluents to give 3.2 g of 3-bromoimidazo[1,2-a]pyrimidine.
References
[1] European Journal of Medicinal Chemistry, 1991, vol. 26, # 1, p. 13 - 18
[2] Chemical and Pharmaceutical Bulletin, 1992, vol. 40, # 5, p. 1170 - 1176
[3] Patent: KR2017/126059, 2017, A. Location in patent: Paragraph 0069; 0072; 0073; 0078; 0079
3-Bromoimidazo[1,2-a]pyrimidine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xuchang Fengfei New Materials Technology Co., Ltd | 19713077352; 19713077352 | 1038096457@qq.com | China | 2333 | 58 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shangchem Co., Ltd. | +86-21-68182121 | China | 881 | 52 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Latest Price from 3-Bromoimidazo[1,2-a]pyrimidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-20 | 3-Bromoimidazo[1,2-a]pyrimidine
6840-45-5
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
![]() |
2026-06-30 | 3-Bromoimidazo[1,2-a]pyrimidine
6840-45-5
|
1KG | 98 | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
![]() |
2020-01-13 | 3-Bromoimidazo[1,2-a]pyrimidine
6840-45-5
|
$5.50 | 1ASSAYS | 98%min | 1kg-100kg | Career Henan Chemical Co |
-
![3-Bromoimidazo[1,2-a]pyrimidine pictures](/ProductImageEN/2021-12/Small/278b9c92-9200-4e85-baad-2377531e1088.jpg)
- 3-Bromoimidazo[1,2-a]pyrimidine
6840-45-5
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
![3-Bromoimidazo[1,2-a]pyrimidine pictures](/ProductImageEN2/2025-12/Small/c9a5a9f9-f1a6-460e-8977-7fb44714e45d.gif)
- 3-Bromoimidazo[1,2-a]pyrimidine
6840-45-5
- 98
- Shaanxi Dideu New Materials Co. Ltd
-
![3-Bromoimidazo[1,2-a]pyrimidine pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/dac010d0-c44e-46d6-8862-074fc2d1e575.jpg)
- 3-Bromoimidazo[1,2-a]pyrimidine
6840-45-5
- $5.50
- 98%min
- Career Henan Chemical Co
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