ENDOMORPHIN-2
- CAS No.
- 141801-26-5
- Chemical Name:
- ENDOMORPHIN-2
- Synonyms
- Tetrapeptide-15;YPFF-NH2;ENDOMORPHIN-2;TYR-PRO-PHE-PHE-NH2;H-TYR-PRO-PHE-PHE-NH2;ENDOMORPHIN-2 (HUMAN, BOVINE);ENDOMORPHIN 2;H-TYR-PRO-PHE-PHE-NH2;Endomorphin 2, mu opioid receptor agonist;L-Tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide;L-Phenylalaninamide,L-tyrosyl-L-prolyl-L-phenylalanyl-
- CBNumber:
- CB7208674
- Molecular Formula:
- C32H37N5O5
- Molecular Weight:
- 571.67
- MDL Number:
- MFCD01321064
- MOL File:
- 141801-26-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 130-131℃ |
|---|---|
| Boiling point | 972.4±65.0 °C(Predicted) |
| Density | 1.292±0.06 g/cm3(Predicted) |
| RTECS | SQ7316100 |
| storage temp. | −20°C |
| solubility | ≥ 57.2mg/mL in DMSO |
| form | Solid |
| pka | 9.86±0.15(Predicted) |
| color | White to off-white |
| Water Solubility | Soluble to 0.40 mg/ml in water |
| Sequence | Tyr-Pro-Phe-Phe-NH2 |
| CAS DataBase Reference | 141801-26-5(CAS DataBase Reference) |
| FDA UNII | 3PH5M0466G |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
ENDOMORPHIN-2 price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | E2291-25C | Endomorphin 2 Purified | 400ug | $1190 | 2026-06-03 | Buy | |
| Biosynth | FE109150 | Endomorphin-2 trifluoroacetate salt | 141801-26-5 | 25mg | $900 | 2026-06-04 | Buy |
| Biosynth | FE109150 | Endomorphin-2 trifluoroacetate salt | 141801-26-5 | 10mg | $900 | 2026-06-04 | Buy |
| Biosynth | FE109150 | Endomorphin-2 trifluoroacetate salt | 141801-26-5 | 5mg | $900 | 2026-06-04 | Buy |
| Biosynth | FE109150 | Endomorphin-2 trifluoroacetate salt | 141801-26-5 | 50mg | $1118.5 | 2026-06-04 | Buy |
ENDOMORPHIN-2 Chemical Properties, Uses, Production
Uses
Endomorphin-2 is a potent and selective endogenous agonist for the μ-opiate receptor.
in vivo
Both Endomorphin 1 and Endomorphin 2 are potent analgesics with peak effects seen at 10 and 15 min, respectively. All subsequent studies are performed at peak effect. Both compounds are fully active supraspinally and spinally, with no indication of ceiling effects. Endomorphin 1 is significantly more potent spinally than supraspinally and, at the spinal level, it is significantly more potent than Endomorphin 2. The response of both agents are readily reversed by naloxone. β-FNA, a highly selective μ antagonist, effectively reverses the actions of both Endomorphins. Neither compound have analgesic activity in CXBK mice at a dose which produced over 70% analgesia in control CD-1 mice[1].
IC 50
μ Opioid Receptor/MOR
storage
-20°C (desiccate)
ENDOMORPHIN-2 Preparation Products And Raw materials
Raw materials
Preparation Products
ENDOMORPHIN-2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Shanghai Xilong Biochemical Technology Co., Ltd. | 021-52907766-8042 | China | 9928 | 58 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Chengdu Huachun Technology Co., Ltd | 400-1166-196 15982826727 | cdhxsj@163.com | China | 14571 | 60 |
View Latest Price from ENDOMORPHIN-2 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-27 | Endomorphin 2
141801-26-5
|
$41.00-74.00 | 99.64% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-02-14 | ENDOMORPHIN-2
141801-26-5
|
$7.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- Endomorphin 2
141801-26-5
- $41.00-74.00
- 99.64%
- TargetMol Chemicals Inc.
-
- ENDOMORPHIN-2
141801-26-5
- $7.00
- 99%
- Career Henan Chemical Co
