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KEMPTIDE

CAS No.
65189-71-1
Chemical Name:
KEMPTIDE
Synonyms
LRRASLG;KEMPTIDE;Nsc332190;KEMPTIDE ACETATE;5-TMR-LRRA-PS-LG;KEMPTIDE [LRRASLG];KEMPTIDE ACETATE SALT;PHOSPHATE ACCEPTOR PEPTIDE;LEU-ARG-ARG-ALA-SER-LEU-GLY;LEU-ARG-ARG-ALA-SER-LEU-GLY-OH
CBNumber:
CB7234741
Molecular Formula:
C32H61N13O9
Molecular Weight:
771.91
MDL Number:
MFCD00076710
MOL File:
65189-71-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-20 15:45:00

KEMPTIDE Properties

Density 1.43±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: 20 mg/mL
form powder
pka 3.32±0.10(Predicted)
color white
Water Solubility Soluble in water (20 mg/ml).
Sequence H-Leu-Arg-Arg-Ala-Ser-Leu-Gly-OH

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3
3-10
HS Code  35079090

KEMPTIDE price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 15555 Kemptide ≥95% 65189-71-1 1mg $49 2026-04-30 Buy
Cayman Chemical 15555 Kemptide ≥95% 65189-71-1 5mg $154 2026-04-30 Buy
Cayman Chemical 15555 Kemptide ≥95% 65189-71-1 10mg $283 2026-04-30 Buy
Cayman Chemical 15555 Kemptide ≥95% 65189-71-1 25mg $645 2026-04-30 Buy
Biosynth PK17023 Kemptide 65189-71-1 1mg $150 2026-06-04 Buy
Product number Packaging Price Buy
15555 1mg $49 Buy
15555 5mg $154 Buy
15555 10mg $283 Buy
15555 25mg $645 Buy
PK17023 1mg $150 Buy

KEMPTIDE Chemical Properties, Uses, Production

Uses

Kemptide, phosphate acceptor, is shown to be a basic serine-containing heptapeptide corresponding to a sequence from pig liver pyruvate kinase. This synthetic peptide is a substrate of PKA (cyclic AMP-dependent protein kinase) and is phosphorylated and activated after microinjection into Xenopus oocytes. Exposure of Kemptide to insulin has demonstrated an increase in activation of this agent, which can be inhibited by the catalytic subunit of phosphatase 2A.

Biological Activity

kemptide is a synthetic heptapeptide that acts as a substrate for camp-dependent protein kinase (pk) [1].cyclic amp-dependent protein kinase is the sole intracellular acceptor for cyclic amp in all cell types. protein phosphorylation by different types of protein kinase (pk) activities comprises a form of protein modification that plays an important role in the regulation of numerous biological processes [1][2].kemptide is a novel synthetic heptapeptide phosphate acceptor that acts as a substrate for camp-dependent protein kinase. kemptide had all the properties of a cytophilic substrate and could preserving cell membrane intactness when added to cultured cells. in the presence of extracellular atp and camp, different types of intact cells catalyzed the phosphorylation of kemptide with km values of 3-4 μm. kemptide phosphorylation was influenced by pki, the inhibitory protein specific for camp-pk [1]. kemptide was usually used as a substrate for detection of activities of soluble a-kinase isolated from guinea-pig lung parenchyma and from bovine tracheal smooth muscle [2][3].

References

[1]. kübler d, pyerin w, bill o, et al. evidence for ecto-protein kinase activity that phosphorylates kemptide in a cyclic amp-dependent mode. j biol chem. 1989 aug 25;264(24):14549-55.
[2]. giembycz ma, diamond j. evaluation of kemptide, a synthetic serine-containing heptapeptide, as a phosphate acceptor for the estimation of cyclic amp-dependent protein kinase activity in respiratory tissues. biochem pharmacol. 1990 jan 15;39(2):271-83.
[3]. langlands jm, rodger iw. determination of soluble camp-dependent protein kinase activity in guinea-pig tracheal smooth muscle. preferential use of kemptide as a phosphorylating substrate. biochem pharmacol. 1990 apr 15;39(8):1365-74.

KEMPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

KEMPTIDE Suppliers

Global Suppliers ( 130)
Supplier Tel Email Country ProdList Advantage
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Cellmano Biotech Limited 0551-65326643 18156095617 info@cellmano.com China 1010 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
Watson Biotechnology Co.,Ltd 027-59207879 1972026995 18140587686 sales@3600chem.com China 4187 55
Creative Peptides info@creative-peptides.com United States 6083 56
Shanghai Xilong Biochemical Technology Co., Ltd. 021-52907766-8042 China 9928 58

View Latest Price from KEMPTIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	KEMPTIDE pictures 2020-02-19 KEMPTIDE
65189-71-1
$7.00 1KG 99% 100kg Career Henan Chemical Co
  • 	KEMPTIDE pictures
  • KEMPTIDE
    65189-71-1
  • $7.00
  • 99%
  • Career Henan Chemical Co
L-Leucyl-L-arginyl-L-arginyl-L-alanyl-L-seryl-L-leucylglycine Glycine,L-leucyl-L-arginyl-L-arginyl-L-alanyl-L-seryl-L-leucyl- Kemptide acetate salt, ≥95% (HPLC) LRRASLG LEU-ARG-ARG-ALA-SER-LEU-GLY LEU-ARG-ARG-ALA-SER-LEU-GLY-OH KEMPTIDE [LRRASLG] KEMPTIDE ACETATE SALT KEMPTIDE H-LEU-ARG-ARG-ALA-SER-LEU-GLY-OH ARG-ARG-LYS-ALA-SER-GLY-PRO-PRO-VAL PHOSPHATE ACCEPTOR PEPTIDE PHOSPHATE ACCEPTOR PEPTIDE ACETATE SALT KEMPTIDE ACETATE H-Arg-Arg-Lys-Ala-Ser-Gly-Pro-Pro-Val-OH Nsc332190 Polypeptide (boehringer) 600925 5-TMR-LEU-ARG-ARG-ALA-PSER-LEU-GLY-OH 5-TMR-LRRA-PS-LG [PSER5]-KEMPTIDE, 5-TMR LABELED 65189-71-1 Cell Biology Cell Signaling and Neuroscience BioChemical Kinase/Phosphatase Biology Protein Kinase A (PKA) Serine/Threonine Kinase Substrates Peptide