H-D-Pro-Phe-Arg-PNA 2 HCl
- CAS No.
- 62354-56-7
- Chemical Name:
- H-D-Pro-Phe-Arg-PNA 2 HCl
- Synonyms
- pFR-pNA;H-D-Pro-Phe-Arg-PNA 2 HCl;H-D-Pro-Phe-Arg-pNA ·2HCI;S-2302 (Chromogenic substrate);D-Pro-Phe-Arg-pNA (hydrochloride);D-pro-phe-arg P-nitroanilide*dihydrochloride;L-Argininamide,D-prolyl-L-phenylalanyl-N-(4-nitrophenyl)-,dihydrochloride
- CBNumber:
- CB7243631
- Molecular Formula:
- C26H36Cl2N8O5
- Molecular Weight:
- 611.52
- MDL Number:
- MFCD00274447
- MOL File:
- 62354-56-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Hazard Codes | Xn |
|---|---|
| Risk Statements | 20/21/22-33-36/37/38-63 |
| Safety Statements | 28-36/37-45 |
| WGK Germany | 3 |
H-D-Pro-Phe-Arg-PNA 2 HCl price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 27569 | D-Pro-Phe-Arg-pNA (hydrochloride) ≥95% | 62354-56-7 | 25mg | $90 | 2026-04-30 | Buy |
| Cayman Chemical | 27569 | D-Pro-Phe-Arg-pNA (hydrochloride) ≥95% | 62354-56-7 | 50mg | $168 | 2026-04-30 | Buy |
| Cayman Chemical | 27569 | D-Pro-Phe-Arg-pNA (hydrochloride) ≥95% | 62354-56-7 | 100mg | $315 | 2026-04-30 | Buy |
| Cayman Chemical | 27569 | D-Pro-Phe-Arg-pNA (hydrochloride) ≥95% | 62354-56-7 | 250mg | $696 | 2026-04-30 | Buy |
| Biosynth | FP110816 | H-D-Pro-Phe-Arg-pNA·2 HCl | 62354-56-7 | 25mg | $343.75 | 2026-06-04 | Buy |
H-D-Pro-Phe-Arg-PNA 2 HCl Chemical Properties, Uses, Production
Description
D-Pro-Phe-Arg-pNA is a colorimetric substrate for plasma kallikrein. Plasma kallikrein preferentially binds to and cleaves the D-Pro-Phe-Arg (PFR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasma kallikrein activity.
Uses
D-Pro-Phe-Arg-pNA hydrochloride is the substrate for thrombin-like enzyme, with Km of 50.7 μM[1].
References
[1] Magalhes HP, et al., Mechanism of action and determination of the best substrate for a thrombin-like enzyme from Lachesis muta muta venom by regression analysis of the kinetic parameters determined with peptidyl p-nitroanilide substrates. Toxicon. 2006 Mar 15;47(4):453-8. DOI:10.1016/j.toxicon.2006.01.001
H-D-Pro-Phe-Arg-PNA 2 HCl Preparation Products And Raw materials
Raw materials
Preparation Products
H-D-Pro-Phe-Arg-PNA 2 HCl Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd. | 0755-23251735 13302967066 | sales@geneseqtools.com | China | 1466 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 18108052721 | 2850505130@qq.com | China | 5037 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
View Latest Price from H-D-Pro-Phe-Arg-PNA 2 HCl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-26 | D-Pro-Phe-Arg-pNA hydrochloride
62354-56-7
|
$146.00 | 99.93% | 10g | TargetMol Chemicals Inc. |
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- D-Pro-Phe-Arg-pNA hydrochloride
62354-56-7
- $146.00
- 99.93%
- TargetMol Chemicals Inc.




