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H-D-Pro-Phe-Arg-PNA 2 HCl

CAS No.
62354-56-7
Chemical Name:
H-D-Pro-Phe-Arg-PNA 2 HCl
Synonyms
pFR-pNA;H-D-Pro-Phe-Arg-PNA 2 HCl;H-D-Pro-Phe-Arg-pNA ·2HCI;S-2302 (Chromogenic substrate);D-Pro-Phe-Arg-pNA (hydrochloride);D-pro-phe-arg P-nitroanilide*dihydrochloride;L-Argininamide,D-prolyl-L-phenylalanyl-N-(4-nitrophenyl)-,dihydrochloride
CBNumber:
CB7243631
Molecular Formula:
C26H36Cl2N8O5
Molecular Weight:
611.52
MDL Number:
MFCD00274447
MOL File:
62354-56-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:49

H-D-Pro-Phe-Arg-PNA 2 HCl Properties

storage temp. -15°C
solubility DMF: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
form A crystalline solid
Sequence {d-Pro}-Phe-Arg-{pNA}

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
Risk Statements  20/21/22-33-36/37/38-63
Safety Statements  28-36/37-45
WGK Germany  3

H-D-Pro-Phe-Arg-PNA 2 HCl price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27569 D-Pro-Phe-Arg-pNA (hydrochloride) ≥95% 62354-56-7 25mg $90 2026-04-30 Buy
Cayman Chemical 27569 D-Pro-Phe-Arg-pNA (hydrochloride) ≥95% 62354-56-7 50mg $168 2026-04-30 Buy
Cayman Chemical 27569 D-Pro-Phe-Arg-pNA (hydrochloride) ≥95% 62354-56-7 100mg $315 2026-04-30 Buy
Cayman Chemical 27569 D-Pro-Phe-Arg-pNA (hydrochloride) ≥95% 62354-56-7 250mg $696 2026-04-30 Buy
Biosynth FP110816 H-D-Pro-Phe-Arg-pNA·2 HCl 62354-56-7 25mg $343.75 2026-06-04 Buy
Product number Packaging Price Buy
27569 25mg $90 Buy
27569 50mg $168 Buy
27569 100mg $315 Buy
27569 250mg $696 Buy
FP110816 25mg $343.75 Buy

H-D-Pro-Phe-Arg-PNA 2 HCl Chemical Properties, Uses, Production

Description

D-Pro-Phe-Arg-pNA is a colorimetric substrate for plasma kallikrein. Plasma kallikrein preferentially binds to and cleaves the D-Pro-Phe-Arg (PFR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasma kallikrein activity.

Uses

D-Pro-Phe-Arg-pNA hydrochloride is the substrate for thrombin-like enzyme, with Km of 50.7 μM[1].

References

[1] Magalhes HP, et al., Mechanism of action and determination of the best substrate for a thrombin-like enzyme from Lachesis muta muta venom by regression analysis of the kinetic parameters determined with peptidyl p-nitroanilide substrates. Toxicon. 2006 Mar 15;47(4):453-8. DOI:10.1016/j.toxicon.2006.01.001

H-D-Pro-Phe-Arg-PNA 2 HCl Preparation Products And Raw materials

Raw materials

Preparation Products

H-D-Pro-Phe-Arg-PNA 2 HCl Suppliers

Global Suppliers ( 46)
Supplier Tel Email Country ProdList Advantage
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659 sales@njleonbiotech.com China 5501 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9976 55
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799 Eric@peptidego.com China 7872 58
Shenzhen GeneSeqTools Bioscience & Technology Co. Ltd. 0755-23251735 13302967066 sales@geneseqtools.com China 1466 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Chengdu Peter-like Biotechnology Co., Ltd. 18108052721 2850505130@qq.com China 5037 58
BOC Sciences +1-631-485-4226 inquiry@bocsci.com United States 19935 58

View Latest Price from H-D-Pro-Phe-Arg-PNA 2 HCl manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
D-Pro-Phe-Arg-pNA hydrochloride pictures 2026-08-26 D-Pro-Phe-Arg-pNA hydrochloride
62354-56-7
$146.00 99.93% 10g TargetMol Chemicals Inc.
pFR-pNA D-pro-phe-arg P-nitroanilide*dihydrochloride D-Pro-Phe-Arg-pNA (hydrochloride) L-Argininamide,D-prolyl-L-phenylalanyl-N-(4-nitrophenyl)-,dihydrochloride S-2302 (Chromogenic substrate) H-D-Pro-Phe-Arg-pNA ·2HCI H-D-Pro-Phe-Arg-PNA 2 HCl 62354-56-7 C26H34N8O52HCl