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5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID

CAS No.
56172-36-2
Chemical Name:
5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID
Synonyms
5-hydroxy-2-Benzofurancarboxylic acid;5-HYDROXY-BENZOFURAN-2-CARBOXYLIC ACID;2-Benzofurancarboxylic acid, 5-hydroxy-;5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID
CBNumber:
CB72455898
Molecular Formula:
C9H6O4
Molecular Weight:
178.14
MDL Number:
MFCD11101014
MOL File:
56172-36-2.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:51
Product description Number Pack Size Price
5-Hydroxybenzofuran-2-carboxylic acid 302876 100.00mg $62
5-Hydroxybenzofuran-2-carboxylic acid 302876 250.00mg $73
5-Hydroxybenzofuran-2-carboxylic acid 302876 1.00g $154
5-Hydroxybenzofuran-2-carboxylic acid 95+% H51002 100mg $140
5-Hydroxybenzofuran-2-carboxylic acid 95+% H51002 250mg $190

5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID Properties

Melting point 252-254 °C
Boiling point 396.4±22.0 °C(Predicted)
Density 1.518±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka 3.06±0.30(Predicted)

5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 302876 5-Hydroxybenzofuran-2-carboxylic acid 56172-36-2 100.00mg $62 2026-05-19 Buy
Matrix Scientific 302876 5-Hydroxybenzofuran-2-carboxylic acid 56172-36-2 250.00mg $73 2026-05-19 Buy
Matrix Scientific 302876 5-Hydroxybenzofuran-2-carboxylic acid 56172-36-2 1.00g $154 2026-05-19 Buy
Synthonix H51002 5-Hydroxybenzofuran-2-carboxylic acid 95+% 56172-36-2 100mg $140 2026-05-06 Buy
Synthonix H51002 5-Hydroxybenzofuran-2-carboxylic acid 95+% 56172-36-2 250mg $190 2026-05-06 Buy
Product number Packaging Price Buy
302876 100.00mg $62 Buy
302876 250.00mg $73 Buy
302876 1.00g $154 Buy
H51002 100mg $140 Buy
H51002 250mg $190 Buy

5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID Chemical Properties,Uses,Production

Synthesis

5-Methoxybenzofuran-2-carboxylic acid

10242-08-7

5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID

56172-36-2

Step 1: Preparation of 5-hydroxybenzofuran-2-carboxylic acid. 5-Methoxybenzofuran-2-carboxylic acid (1.0 g, 5.2 mmol) was dissolved in anhydrous dichloromethane (25 ml) and the solution was cooled to -78°C. A 1 M solution of boron tribromide dichloromethane (15.6 ml) was added slowly and dropwise under nitrogen protection. The reaction mixture was gradually warmed to room temperature and stirred continuously at this temperature for 4 hours. Upon completion of the reaction, the reaction was quenched with aqueous ammonium chloride solution (20 ml) and subsequently extracted with ethyl acetate. The organic layer was washed with water and dried over anhydrous sodium sulfate. After treatment, 0.9 g (100% yield) of the crude product of 5-hydroxybenzofuran-2-carboxylic acid was obtained.1H NMR (CD3OD) δ = 6.84 (dd, 1H), 6.95 (d, 1H), 7.17 (s, 1H), 7.32 (d, 1H).

References

[1] Patent: US2005/26969, 2005, A1. Location in patent: Page/Page column 12
[2] Patent: WO2008/157270, 2008, A1. Location in patent: Page/Page column 74-75

10242-08-7
56172-36-2
Synthesis of 5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID from 5-Methoxybenzofuran-2-carboxylic acid

5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID Preparation Products And Raw materials

5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID Suppliers

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5-HYDROXY-1-BENZOFURAN-2-CARBOXYLIC ACID 5-HYDROXY-BENZOFURAN-2-CARBOXYLIC ACID 5-hydroxy-2-Benzofurancarboxylic acid 2-Benzofurancarboxylic acid, 5-hydroxy- 56172-36-2