ChemicalBook >> CAS DataBase List >>TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE structure

CAS No.: 930785-40-3

Chemical Name:: TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE

Synonyms: 9-Boc-1-Oxa-4,9-diazaspiro[5.5]undecane;EOS-62238;1-Oxa-9-Boc-4,9-diazaspiro[5.5]undecane;1-Oxa-4,9-diazaspiro[5.5]undecane,N9-BOCprotected;tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecan-9-carboxylate;TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE;tert-butyl1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate 1-;1,1-Dimethylethyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate;tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate - [B13035];1-Oxa-4,9-diaza-spiro[5.5]undecane-9-carboxylic acid tert-butyl ester

CBNumber:: CB72457463

Molecular Formula:: C13H24N2O3

Molecular Weight:: 256.34

MDL Number:: MFCD11227065

MOL File:: 930785-40-3.mol

MSDS File:: SDS

Last updated:2026-05-28 02:37:53

Product description	Number	Pack Size	Price
9-BOC-1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE 97%	52432	1G	$69
9-BOC-1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE 97%	52432	5G	$225
9-BOC-1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE 97%	52432	25G	$1123
tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate	FB134944	50mg	$900
tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate	FB134944	500mg	$900
More product size

Request For Quotation

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE Properties

Boiling point	364.2±42.0 °C(Predicted)
Density	1.11
storage temp.	2-8°C
pka	8.82±0.20(Predicted)
form	crystalline powder
color	White
InChI	InChI=1S/C13H24N2O3/c1-12(2,3)18-11(16)15-7-4-13(5-8-15)10-14-6-9-17-13/h14H,4-10H2,1-3H3
InChIKey	FRROFBJYHIEDPS-UHFFFAOYSA-N
SMILES	O1C2(CCN(C(OC(C)(C)C)=O)CC2)CNCC1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2933399990

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
AstaTech	52432	9-BOC-1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE 97%	930785-40-3	1G	$69	2026-04-30	Buy
AstaTech	52432	9-BOC-1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE 97%	930785-40-3	5G	$225	2026-04-30	Buy
AstaTech	52432	9-BOC-1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE 97%	930785-40-3	25G	$1123	2026-04-30	Buy
Biosynth	FB134944	tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate	930785-40-3	50mg	$900	2026-06-04	Buy
Biosynth	FB134944	tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate	930785-40-3	500mg	$900	2026-06-04	Buy

Product number	Packaging	Price	Buy
52432	1G	$69	Buy
52432	5G	$225	Buy
52432	25G	$1123	Buy
FB134944	50mg	$900	Buy
FB134944	500mg	$900	Buy

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE Chemical Properties,Uses,Production

Synthesis

tert-Butyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate

1160247-07-3

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE

930785-40-3

The reaction was carried out in 12 batches as follows: borane-dimethyl sulfide complex (10 M, dissolved in dimethyl sulfide, 75 mL, 750 mmol) was slowly added dropwise to a solution of tert-butyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate (50 g, 180 mmol) in tetrahydrofuran (1.5 L). The reaction mixture was heated at reflux for 6 h at 70 °C, followed by stirring for 10 h at 25 °C. Upon completion of the reaction, the reaction was quenched with methanol (500 mL) and stirring was continued at 25 °C for 30 min, after which it was concentrated under reduced pressure. The resulting white solid was dissolved in methanol (1 L), N,N'-dimethylethane-1,2-diamine (65 g, 740 mmol) was added, and heated at reflux for 16 hours at 70 °C. Twelve batches of the reaction mixture were combined and concentrated in vacuum to give a pale yellow oil. This oily substance was dissolved in dichloromethane (4 L), washed with aqueous ammonium chloride (4 x 2 L), dried over sodium sulfate, filtered and concentrated under reduced pressure. The residue was ground with petroleum ether (500 mL) at 25°C for 30 min to give a white solid product (304 g). The milled filtrate was concentrated under vacuum and the residue was ground with petroleum ether (200 mL) at 25 °C for 36 h to give additional white solid product (135 g). Total yield: 439 g, 1.71 mol, 77%. lcms m/z 257.2 [M + H]+. 1H NMR (400 MHz, CDCl3) δ 3.85-3.59 (m, 4H), 3.14 (br dd, J = 11,11 Hz, 2H), 2.84 (dd, J = 4.9,4.6 Hz, 2H), 2.68 (s , 2H), 2.02-1.84 (br m, 2H), 1.47-1.33 (m, 2H), 1.45 (s, 9H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 24, p. 7458 - 7461
[2] Patent: WO2017/21805, 2017, A1. Location in patent: Page/Page column 83; 85
[3] Patent: US2018/208608, 2018, A1. Location in patent: Paragraph 0243; 0244; 0246
[4] Patent: WO2015/185207, 2015, A1. Location in patent: Page/Page column 190; 191
[5] Patent: WO2015/185208, 2015, A1. Location in patent: Page/Page column 147; 148

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE Preparation Products And Raw materials

Raw materials

tert-Butyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate N,N'-Dimethyl-1,2-ethanediamine Methanol Tetrahydrofuran Borane-methyl sulfide complex

Preparation Products

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE Suppliers

Global( 108)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	809	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32998	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10399	58
Accela ChemBio Inc.	+1-858-6993322 +86-18019713315	info@accelachem.com	United States	21189	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63645	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
NINGBOBENKANGJS PHARMTECHCO., LTD	+8615990591583 15990591583		CHINA	2028	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
Labnetwork lnc.	+86-27-50766799 +86-18062016861	contact@labnetwork.com	China	19981	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
ATK CHEMICAL COMPANY LIMITED	60
Shenzhen Nexconn Pharmatechs Ltd	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
NINGBOBENKANGJS PHARMTECHCO., LTD	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Labnetwork lnc.	58

View Lastest Price from TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-03-08	TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE 930785-40-3	$3.00	1KG	99%min	500kg	Career Henan Chemical Co

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE
930785-40-3
$3.00
99%min
Career Henan Chemical Co

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE Spectrum

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE(930785-40-3)¹HNMR TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE(930785-40-3)FT-IR

930785-40-3(TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE)Related Search:

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-4-CARBOXYLATE tert-butyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate hydrochloride Tert-Butyl 1-Oxa-4,9-Diazaspiro[5.5]Undecane-4-Carboxylate Hydrochloride benzyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate 9-BENZYL-1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE

tert-butyl 4-benzyl-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate

1of2

TERT-BUTYL 1-OXA-4,9-DIAZASPIRO[5.5]UNDECANE-9-CARBOXYLATE 1-Oxa-4,9-diazaspiro[5.5]undecane-9-carboxylic acid, 1,1-diMethylethyl ester 1-Oxa-4,9-diaza-spiro[5.5]undecane-9-carboxylic acid tert-butyl ester 1-Oxa-4,9-diazaspiro[5.5]undecane,N9-BOCprotected EOS-62238 tert-butyl1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate 1- 1,1-Dimethylethyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate 1-Oxa-9-Boc-4,9-diazaspiro[5.5]undecane tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate - [B13035] tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecan-9-carboxylate 9-Boc-1-Oxa-4,9-diazaspiro[5.5]undecane 930785-40-3