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2,6-Dimethylpyridine-4-boronic acid, pinacol ester

2,6-Dimethylpyridine-4-boronic acid, pinacol ester structure

CAS No.: 325142-95-8

Chemical Name:: 2,6-Dimethylpyridine-4-boronic acid, pinacol ester

Synonyms: 2,6-DiMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine;2,6-Dimethylpyridin-4-boronic acid pinacol ester;2,6-Dimethylpyridin-4-ylboronic acid pinacol ester;2,6-dimethylpyridine-4-borate;2,6-Dimethylpyridine-4-boronic acid, pinacol ester;Pyridine, 2,6-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

CBNumber:: CB72457564

Molecular Formula:: C13H20BNO2

Molecular Weight:: 233.11

MDL Number:: MFCD11617853

MOL File:: 325142-95-8.mol

MSDS File:: SDS

Last updated:2026-09-12 18:54:50

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2,6-Dimethylpyridine-4-boronic acid, pinacol ester Properties

Melting point	82-83 °C
Boiling point	330.1±42.0 °C(Predicted)
Density	1.01±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
pka	5.86±0.10(Predicted)
Appearance	White to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H335-H302+H312+H332-H315
Precautionary statements	P280-P301+P312-P362+P364
HS Code	2933399990

2,6-Dimethylpyridine-4-boronic acid, pinacol ester price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	314013	2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine	325142-95-8	1.00g	$63	2026-05-19	Buy
Matrix Scientific	314013	2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine	325142-95-8	5.00g	$110	2026-05-19	Buy
Matrix Scientific	314013	2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine	325142-95-8	25.00g	$528	2026-05-19	Buy
Synthonix	D32021	2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95+%	325142-95-8	250mg	$55	2026-05-06	Buy
Synthonix	D32021	2,6-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 95+%	325142-95-8	1g	$61	2026-05-06	Buy

Product number	Packaging	Price	Buy
314013	1.00g	$63	Buy
314013	5.00g	$110	Buy
314013	25.00g	$528	Buy
D32021	250mg	$55	Buy
D32021	1g	$61	Buy

2,6-Dimethylpyridine-4-boronic acid, pinacol ester Chemical Properties, Uses, Production

Synthesis

5093-70-9

73183-34-3

325142-95-8

General procedure for the synthesis of 2,6-dimethylpyridine-4-boronic acid pinacol ester from 4-bromo-2,6-dimethylpyridine and bis(boronic acid) pinacol ester: to 4-bromo-2,6-dimethylpyridine (1.00 g, 5.38 mmol), 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bis(1,3,2-dioxaborolane) ( 1.64 g, 6.45 mmol), PdCl2(dppf) (393 mg, 0.537 mmol), and KOAc (1.58 g, 16.12 mmol) was added to a mixture of degassed dioxane solution (2 mL). The reaction mixture was heated and stirred at 85 °C for 18 hours. Upon completion of the reaction, the mixture was dissolved in EtOAc and filtered through a Celite pad. The filtrate was concentrated in vacuum to afford the crude product 2,6-dimethylpyridine-4-boronic acid pinacol ester (1.88 g, 8.07 mmol, quantitative yield) as a brown solid.

References

[1] Patent: WO2016/196644, 2016, A1. Location in patent: Paragraph 274; 275
[2] Patent: WO2018/102452, 2018, A2. Location in patent: Paragraph 258; 259

2,6-Dimethylpyridine-4-boronic acid, pinacol ester Preparation Products And Raw materials

Raw materials

2,6-Lutidine 4-Bromo-2,6-dimethylpyridine Bis(pinacolato)diboron [1,1'-Bis(diphenylphosphino)ferrocene]dichloropalladium(II) Potassium Acetate

1,4-Dioxane

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Preparation Products

2,6-Dimethylpyridine-4-boronic acid, pinacol ester Suppliers

Global Suppliers ( 95)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	sales@chemreagents.com	United States	10174	62
Tetranov Biopharm	13526569071	sales@leadmedpharm.com	China	7881	64
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 13913916777	cfzhang@aikonchem.com	China	19902	55
9ding chemical ( Shanghai) Limited	4009209199	sales@9dingchem.com	China	18201	56
Hebei Summedchem Co.,Ltd	0319-5801333-8008 15630992918	sales@summedchem.com	China	1000	58
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Shanghai Worldyang Chemical Co.,Ltd.	021-56795766	sales@worldyachem.com	China	9475	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Energy Chemical	61
Pure Chemistry Scientific Inc.	62
Tetranov Biopharm	64
Accela ChemBio Co.,Ltd.	64
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	55
9ding chemical ( Shanghai) Limited	56
Hebei Summedchem Co.,Ltd	58
Bide Pharmatech Ltd.	60
Shanghai Worldyang Chemical Co.,Ltd.	58

2,6-Dimethylpyridine-4-boronic acid, pinacol ester Spectrum

2,6-DIMETHYLPYRIDINE-4-BORONIC ACID, PINACOL ESTER(325142-95-8)¹HNMR

325142-95-8 (2,6-Dimethylpyridine-4-boronic acid, pinacol ester) Related Search:

2,6-Dimethyl-pyridine-4-boronic acid 2-Methylpyridine-4-boronic acid pinacol ester 2-Cyanopyridine-4-boronic acid pinacol ester 2,6-di(trideuteromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 2-(methyl-d2)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

6-Methyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile

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Pyridine, 2,6-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 2,6-dimethylpyridine-4-borate 2,6-Dimethylpyridin-4-ylboronic acid pinacol ester 2,6-DiMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine 2,6-Dimethylpyridin-4-boronic acid pinacol ester 2,6-Dimethylpyridine-4-boronic acid, pinacol ester 325142-95-8 C13H20NO2B