7-Chloro-[1,8]naphthyridin-2-ol
![7-Chloro-[1,8]naphthyridin-2-ol Structure](CAS/GIF/15944-34-0.gif)
- CAS No.
- 15944-34-0
- Chemical Name:
- 7-Chloro-[1,8]naphthyridin-2-ol
- Synonyms
- 7-Chloro-1H-[1,8]naphthyridin-2-one;7-Chloro-[1,8]naphthyridin-2-ol;1,8-Naphthyridin-2(1H)-one, 7-chloro-
- CBNumber:
- CB72491645
- Molecular Formula:
- C8H5ClN2O
- Molecular Weight:
- 180.59
- MDL Number:
- MFCD17215762
- MOL File:
- 15944-34-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H335-H319 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
7-Chloro-[1,8]naphthyridin-2-ol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | QAA94434 | 7-Chloro-1,8-naphthyridin-2-ol | 15944-34-0 | 100mg | $342 | 2026-06-04 | Buy |
| Biosynth | QAA94434 | 7-Chloro-1,8-naphthyridin-2-ol | 15944-34-0 | 1g | $1073.8 | 2026-06-04 | Buy |
| Matrix Scientific | 297497 | 7-Chloro-1,8-naphthyridin-2-ol | 15944-34-0 | 100.00mg | $139 | 2026-05-19 | Buy |
| Matrix Scientific | 297497 | 7-Chloro-1,8-naphthyridin-2-ol | 15944-34-0 | 250.00mg | $269 | 2026-05-19 | Buy |
| Matrix Scientific | 297497 | 7-Chloro-1,8-naphthyridin-2-ol | 15944-34-0 | 1.00g | $506 | 2026-05-19 | Buy |
7-Chloro-[1,8]naphthyridin-2-ol Chemical Properties, Uses, Production
Synthesis
![3-Pyridinepropanoic acid, 6-chloro-2-[(2,2-dimethyl-1-oxopropyl)amino]-β-hydroxy-, 1,1-dimethylethyl ester](/CAS/20210305/GIF/127446-41-7.gif)
127446-41-7
![7-Chloro-[1,8]naphthyridin-2-ol](/CAS/GIF/15944-34-0.gif)
15944-34-0
Tert-butyl 3-[6-chloro-2-(2,2-dimethylpropanamido)pyridin-3-yl]-3-hydroxypropanoate (4 g, 11 mmol) was used as a raw material, which was dissolved in a mixed solution of 1 M HCl/dioxane (1:1, 50 mL) and reacted overnight. After completion of the reaction, ice water was added to the mixture and the precipitated solid was collected by filtration and dried to afford 7-chloro-1,8-diazanaphthalen-2-ol (1.7 g, 9.4 mmol, 86% yield). The obtained product could be used in the subsequent reaction without further purification.LC-MS analysis showed the (M-H)-peak was 181.1.
References
[1] Journal of Organic Chemistry, 1990, vol. 55, # 15, p. 4744 - 4750
[2] Patent: WO2017/211759, 2017, A1. Location in patent: Page/Page column 94
7-Chloro-[1,8]naphthyridin-2-ol Preparation Products And Raw materials
7-Chloro-[1,8]naphthyridin-2-ol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Atop-Pharma (Shanghai) Technology Co., Ltd. | +86 (21) 5196-9732 | China | 996 | 57 | |
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| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
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