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4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester

CAS No.
656257-45-3
Chemical Name:
4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester
Synonyms
4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpicolester;4-(4-Ethylpiperazino)phenylboronic Acid Pinacol Ester;4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester;1-Ethyl-4-[4-(4.4.5.5-tetraMethyl-1.3.2-dioxaborolan-2-yl)phenyl]piperazine;Piperazine, 1-ethyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-
CBNumber:
CB72498280
Molecular Formula:
C18H29BN2O2
Molecular Weight:
316.25
MDL Number:
MFCD13190738
MOL File:
656257-45-3.mol
Last updated:2026-05-28 03:17:10

4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Synthonix E59322 4-(4-Ethylpiperazin-1-yl)phenylboronic acid pinacol ester 95+% 656257-45-3 100mg $16 2026-05-06 Buy
Synthonix E59322 4-(4-Ethylpiperazin-1-yl)phenylboronic acid pinacol ester 95+% 656257-45-3 250mg $22 2026-05-06 Buy
Synthonix E59322 4-(4-Ethylpiperazin-1-yl)phenylboronic acid pinacol ester 95+% 656257-45-3 1g $50 2026-05-06 Buy
Synthonix E59322 4-(4-Ethylpiperazin-1-yl)phenylboronic acid pinacol ester 95+% 656257-45-3 5g $270 2026-05-06 Buy
Synthonix E59322 4-(4-Ethylpiperazin-1-yl)phenylboronic acid pinacol ester 95+% 656257-45-3 10g $1240 2026-05-06 Buy
Product number Packaging Price Buy
E59322 100mg $16 Buy
E59322 250mg $22 Buy
E59322 1g $50 Buy
E59322 5g $270 Buy
E59322 10g $1240 Buy

4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester Chemical Properties, Uses, Production

Uses

1-Ethyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine

Synthesis

Pinacolborane

25015-63-8

1-(4-BroMophenyl)-4-ethylpiperazine

656257-43-1

4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester

656257-45-3

1-(4-Bromophenyl)-4-ethylpiperazine (3 g, 11 mmol) and pinacolborane were dissolved in dioxane (100 mL) and then 4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1.8 g, 12 mmol), dichlorobis(triphenylphosphine)palladium(II) (0.392 g, 0.57 mmol) and triethylamine (4.65 g, 33 mmol). The reaction mixture was heated to reflux for 12 hours. After completion of the reaction, the mixture was poured into water and extracted with dichloromethane. The organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography with dichloromethane/methanol (9/1, v/v) as eluent. 4-(4-Ethyl-1-piperazinyl)phenylboronic acid pinacol ester was obtained as a brown oil, which crystallized on standing (2 g, yield 55.48%), melting point 130-134°C.

References

[1] Patent: WO2004/13134, 2004, A2. Location in patent: Page 27; 28
[2] Patent: WO2004/13135, 2004, A1. Location in patent: Page 49

4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester Preparation Products And Raw materials

Global Suppliers ( 46)
Supplier Tel Email Country ProdList Advantage
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai civi chemical technology co.,Ltd 86-21-34053660 sale@labgogo.com China 9853 52
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. +86-28-85122536 85324413 market@astatech.cn China 8016 55
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189;18621755571 mychess007@163.com China 1994 55
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
Changsha Luxing Bio-Chem Technology Co., Ltd. 0731-88827538 15574813303 luxingbc@126.com China 1975 65
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Atop Bio-Tech (Tianjin) Co., Ltd. (Atop) 022-66200236 18622210341 sales@atop-biotech.com China 295 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58

View Latest Price from 4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester pictures 2019-07-06 4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester
656257-45-3
$1.00 1KG 95% 500KG Career Henan Chemical Co

4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester Spectrum

4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpinacolester 1-Ethyl-4-[4-(4.4.5.5-tetraMethyl-1.3.2-dioxaborolan-2-yl)phenyl]piperazine 4-(4-Ethylpiperazino)phenylboronic Acid Pinacol Ester 4-(4-Ethylpiperazin-1-yl)-phenylboronicacidpicolester Piperazine, 1-ethyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]- 656257-45-3