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Benzyl 6-aminonicotinate

CAS No.
935687-49-3
Chemical Name:
Benzyl 6-aminonicotinate
Synonyms
6-aminoacidbenzyl ester;Benzyl 6-aminonicotinate;6-Aminonicotinic acid benzyl ester;Benzyl 6-aminopyridine-3-carboxylate;2-Amino-5-(benzyloxycarbonyl)pyridine;3-Pyridinecarboxylic acid, 6-amino-, phenylmethyl ester
CBNumber:
CB72502482
Molecular Formula:
C13H12N2O2
Molecular Weight:
228.25
MDL Number:
MFCD12913991
MOL File:
935687-49-3.mol
MSDS File:
SDS
Last updated:2026-05-28 03:24:35

Benzyl 6-aminonicotinate Properties

Boiling point 420.5±30.0 °C(Predicted)
Density 1.243±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 4.71±0.13(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933399990

Benzyl 6-aminonicotinate price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 200360 6-Aminonicotinic acid benzyl ester 935687-49-3 5.00g $874 2026-05-18 Buy
Matrix Scientific 200360 6-Aminonicotinic acid benzyl ester 935687-49-3 25.00g $1463 2026-05-18 Buy
aablocks AA003O12 Benzyl 6-Aminonicotinate 96% 935687-49-3 100mg $52 2026-05-28 Buy
aablocks AA003O12 Benzyl 6-Aminonicotinate 96% 935687-49-3 250mg $96 2026-05-28 Buy
aablocks AA003O12 Benzyl 6-Aminonicotinate 96% 935687-49-3 1g $190 2026-05-28 Buy
Product number Packaging Price Buy
200360 5.00g $874 Buy
200360 25.00g $1463 Buy
AA003O12 100mg $52 Buy
AA003O12 250mg $96 Buy
AA003O12 1g $190 Buy

Benzyl 6-aminonicotinate Chemical Properties, Uses, Production

Synthesis

6-Aminonicotinic acid

3167-49-5

Benzyl bromide

100-39-0

Benzyl 6-aminonicotinate

935687-49-3

Example 46 Procedure for the synthesis of benzyl 6-{3-[7-fluoro-2-(4-fluorobenzyl)-3-oxo-2,3-dihydro-1H-isoindol-1-yl]-propionylamino}- nicotinate: A. Synthesis of benzyl 6-aminonicotinate: to a mixture of DMF (4 mL) containing 6-aminonicotinic acid (1.0 g, 7.2 mmol) and potassium carbonate (1.5 g, 10.8 mmol), benzyl bromide (0.86 ml, 7.9 mmol) was added. The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the reaction mixture was diluted with water (50 mL) and extracted with ethyl acetate (3 x 50 mL). The organic layers were combined, washed with saturated brine, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give the crude product. The crude product was recrystallized with ether to give the title compound as a light yellow solid (0.88 g, 53% yield).

References

[1] Patent: WO2010/29461, 2010, A1. Location in patent: Page/Page column 65-66
[2] Patent: US2007/99930, 2007, A1. Location in patent: Page/Page column 48
[3] Patent: US2011/190267, 2011, A1. Location in patent: Page/Page column 53
[4] Journal of Medicinal Chemistry, 2012, vol. 55, # 3, p. 1318 - 1333

3167-49-5
100-39-0
935687-49-3
Synthesis of Benzyl 6-aminonicotinate from 6-Aminonicotinic acid and Benzyl bromide

Benzyl 6-aminonicotinate Preparation Products And Raw materials

Benzyl 6-aminonicotinate Suppliers

Global Suppliers ( 34)
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Worldyang Chemical Co.,Ltd. 021-56795766 sales@worldyachem.com China 9475 58
Yancheng KangdiSen Pharmaceutical Co., Ltd. 13812573443;18052965989 tongbenwan22@163.com China 1975 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 021-4009004166/18616739031 18616739031 3007523370@qq.com China 40000 58
Labnetwork lnc. +86-27-50766799 +86-18062016861 contact@labnetwork.com China 19981 58
Shanghai Lanle Bird Industrial Co., Ltd. 15021845385 765325601@qq.com China 3607 58
Qi Qi hang Biotechnology Co., Ltd. 18151111370 1046215251@qq.com China 5999 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
Benzyl 6-aminonicotinate Benzyl 6-aminopyridine-3-carboxylate 2-Amino-5-(benzyloxycarbonyl)pyridine 6-Aminonicotinic acid benzyl ester 3-Pyridinecarboxylic acid, 6-amino-, phenylmethyl ester 6-aminoacidbenzyl ester 935687-49-3