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GW 610

CAS No.
872726-44-8
Chemical Name:
GW 610
Synonyms
NSC 721648;GW 610;NSC 721648 PMX 610;GW 610, 10 mM in DMSO;PMX 610 NSC 721648 W 610;NSC 721648 - CAS 872726-44-8 - Calbiochem;2-(3,4-Dimethoxyphenyl)-5-fluorobenzo[d]thiazole;Benzothiazole, 2-(3,4-dimethoxyphenyl)-5-fluoro-;GW 610,colon,Inhibitor,GW610,NSC721648,inhibit,breast,antitumor,NSC 721648,lung,GW-610,NSC-721648
CBNumber:
CB72591189
Molecular Formula:
C15H12FNO2S
Molecular Weight:
289.3246832
MDL Number:
MFCD12024619
MOL File:
872726-44-8.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08

GW 610 Properties

Melting point 110 °C
Boiling point 422.8±55.0 °C(Predicted)
Density 1.293±0.06 g/cm3(Predicted)
storage temp. +2C to +8C
solubility DMF:10.0(Max Conc. mg/mL);34.56(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.86(Max Conc. mM)
DMSO:9.5(Max Conc. mg/mL);32.84(Max Conc. mM)
form White crystalline solid
pka 0.73±0.10(Predicted)
color Light yellow to brown
FDA UNII X3XWA9LQ3Q

GW 610 price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10008313 GW 610 ≥98% 872726-44-8 1mg $25 2026-04-30 Buy
Cayman Chemical 10008313 GW 610 ≥98% 872726-44-8 5mg $105 2026-04-30 Buy
Cayman Chemical 10008313 GW 610 ≥98% 872726-44-8 10mg $184 2026-04-30 Buy
Cayman Chemical 10008313 GW 610 ≥98% 872726-44-8 50mg $796 2026-04-30 Buy
Usbiological 013023 GW 610 872726-44-8 10mg $425 2026-06-03 Buy
Product number Packaging Price Buy
10008313 1mg $25 Buy
10008313 5mg $105 Buy
10008313 10mg $184 Buy
10008313 50mg $796 Buy
013023 10mg $425 Buy

GW 610 Chemical Properties, Uses, Production

Description

GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI50) < 0.1 nM) was observed. Potent and selective activity was also observed in the NCI 60 human cancer cell line panel. In contrast with previously reported 2-(4-aminophenyl)benzothiazoles, GW 610 is not reliant on induction of cytochrome P 1A1 (CYP1A1) expression for antitumor activity.

Uses

GW 610 is a fluorinated 2-arylbenzothiazole and potential antitumor drug, which shows potent and selective inhibitory activity against breast, lung, and colon cancer cell lines. Studies suggest that the species-specific partial agonism of the aryl hydrocarbon receptor shown by GW 610 plays an important role in its anti-proliferative activity.

References

[1] CATRIONA G. MORTIMER. Antitumor Benzothiazoles. 26.1 2-(3,4-Dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a Simple Fluorinated 2-Arylbenzothiazole, Shows Potent and Selective Inhibitory Activity against Lung, Colon, and Breast Cancer Cell Lines[J]. Journal of Medicinal Chemistry, 2005, 49 1: 179-185. DOI: 10.1021/jm050942k

GW 610 Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 60)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8039 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9777 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233 690231469@qq.com China 8000 58

View Latest Price from GW 610 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GW 610 pictures 2026-08-08 GW 610
872726-44-8
$58.00-151.00 99.50% 10g TargetMol Chemicals Inc.
  • GW 610 pictures
  • GW 610
    872726-44-8
  • $58.00-151.00
  • 99.50%
  • TargetMol Chemicals Inc.

GW 610 Spectrum

GW 610 NSC 721648 - CAS 872726-44-8 - Calbiochem NSC 721648 PMX 610 GW 610,colon,Inhibitor,GW610,NSC721648,inhibit,breast,antitumor,NSC 721648,lung,GW-610,NSC-721648 Benzothiazole, 2-(3,4-dimethoxyphenyl)-5-fluoro- 2-(3,4-Dimethoxyphenyl)-5-fluorobenzo[d]thiazole PMX 610 NSC 721648 W 610 GW 610, 10 mM in DMSO NSC 721648 872726-44-8 Aromatics Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals