Ethyl 7-chloroindole-2-carboxylate
- CAS No.
- 43142-64-9
- Chemical Name:
- Ethyl 7-chloroindole-2-carboxylate
- Synonyms
- Ethyl 7-chloroindole-2-carboxylate;1H-Indole-2-carboxylic acid, 7-chloro-, ethyl ester
- CBNumber:
- CB72604445
- Molecular Formula:
- C11H10ClNO2
- Molecular Weight:
- 223.66
- MDL Number:
- MFCD14715880
- MOL File:
- 43142-64-9.mol
- MSDS File:
- SDS
| Melting point | 105 °C |
|---|---|
| Boiling point | 375.0±22.0 °C(Predicted) |
| Density | 1.329±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 13.43±0.30(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C11H10ClNO2/c1-2-15-11(14)9-6-7-4-3-5-8(12)10(7)13-9/h3-6,13H,2H2,1H3 |
| InChIKey | HPDPSWAIDXFYTE-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC=C2Cl)C=C1C(OCC)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H315-H319-H412 |
| Precautionary statements | P501-P273-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P310+P330-P405 |
Ethyl 7-chloroindole-2-carboxylate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 100mg | $15 | 2026-05-06 | Buy |
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 250mg | $21 | 2026-05-06 | Buy |
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 1g | $30 | 2026-05-06 | Buy |
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 5g | $80 | 2026-05-06 | Buy |
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 10g | $1180 | 2026-05-06 | Buy |
Ethyl 7-chloroindole-2-carboxylate Chemical Properties,Uses,Production
Uses
Ethyl 7-chloroindole-2-carboxylate is an organic synthesis intermediate, mainly used in the synthesis of drugs and pesticide molecules containing indole rings, and is also an important component in chemical research.
Synthesis
![ethyl 2-[2-(2-chlorophenyl)hydrazinylidene]propanoate](/CAS/20210111/GIF/115050-49-2.gif)
115050-49-2
43142-64-9
General procedure for the synthesis of ethyl 7-chloro-1H-indole-2-carboxylate from the compound (CAS:115050-49-2): 500 g of polyphosphoric acid and 250 g of phosphoric acid were mixed, stirred and heated up to 90°C. Under stirring conditions, 65 g of phenylhydrazine 2-chlorophenylpyruvate pyruvic acid was slowly added and the temperature of the reaction was controlled to be between 90°C and 100°C. The reaction took about 1 hour. The dosing process takes about 1 hour. After completion of dosing, the reaction temperature was maintained to continue the reaction for 20 minutes and the reaction progress was monitored by TLC. Upon completion of the reaction, 1500 g of ice-water mixture was slowly added to quench the reaction and cooled to room temperature. The precipitate was collected by filtration, washed with water and dried to give a light yellow solid product. Upon drying, 51.3 g of ethyl 7-chloro-1H-indole-2-carboxylate was obtained in 85% yield.
References
[1] Patent: CN104402795, 2017, B. Location in patent: Paragraph 0060; 0062
Ethyl 7-chloroindole-2-carboxylate Preparation Products And Raw materials
Ethyl 7-chloroindole-2-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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| Zhanhua Huibang Chemical Co., Ltd. | 13906149256 | 793211102@qq.com | China | 152 | 58 |
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View Lastest Price from Ethyl 7-chloroindole-2-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | Ethyl 7-chloroindole-2-carboxylate
43142-64-9
|
$1.00-22.00 | 1KG | 99% | 100000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- Ethyl 7-chloroindole-2-carboxylate
43142-64-9
- $1.00-22.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
