Ethyl 7-chloroindole-2-carboxylate
- CAS No.
- 43142-64-9
- Chemical Name:
- Ethyl 7-chloroindole-2-carboxylate
- Synonyms
- Ethyl 7-chloroindole-2-carboxylate;1H-Indole-2-carboxylic acid, 7-chloro-, ethyl ester
- CBNumber:
- CB72604445
- Molecular Formula:
- C11H10ClNO2
- Molecular Weight:
- 223.66
- MDL Number:
- MFCD14715880
- MOL File:
- 43142-64-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | E54328 | 100mg | $15 |
| Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | E54328 | 250mg | $21 |
| Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | E54328 | 1g | $30 |
| Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | E54328 | 5g | $80 |
| Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | E54328 | 10g | $1180 |
| Melting point | 105 °C |
|---|---|
| Boiling point | 375.0±22.0 °C(Predicted) |
| Density | 1.329±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 13.43±0.30(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C11H10ClNO2/c1-2-15-11(14)9-6-7-4-3-5-8(12)10(7)13-9/h3-6,13H,2H2,1H3 |
| InChIKey | HPDPSWAIDXFYTE-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC=C2Cl)C=C1C(OCC)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H315-H319-H412 |
| Precautionary statements | P501-P273-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P310+P330-P405 |
Ethyl 7-chloroindole-2-carboxylate price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 100mg | $15 | 2026-05-06 | Buy |
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 250mg | $21 | 2026-05-06 | Buy |
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 1g | $30 | 2026-05-06 | Buy |
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 5g | $80 | 2026-05-06 | Buy |
| Synthonix | E54328 | Ethyl 7-chloro-1H-indole-2-carboxylate 95+% | 43142-64-9 | 10g | $1180 | 2026-05-06 | Buy |
Ethyl 7-chloroindole-2-carboxylate Chemical Properties,Uses,Production
Uses
Ethyl 7-chloroindole-2-carboxylate is an organic synthesis intermediate, mainly used in the synthesis of drugs and pesticide molecules containing indole rings, and is also an important component in chemical research.
Synthesis
![ethyl 2-[2-(2-chlorophenyl)hydrazinylidene]propanoate](/CAS/20210111/GIF/115050-49-2.gif)
115050-49-2
43142-64-9
General procedure for the synthesis of ethyl 7-chloro-1H-indole-2-carboxylate from the compound (CAS:115050-49-2): 500 g of polyphosphoric acid and 250 g of phosphoric acid were mixed, stirred and heated up to 90°C. Under stirring conditions, 65 g of phenylhydrazine 2-chlorophenylpyruvate pyruvic acid was slowly added and the temperature of the reaction was controlled to be between 90°C and 100°C. The reaction took about 1 hour. The dosing process takes about 1 hour. After completion of dosing, the reaction temperature was maintained to continue the reaction for 20 minutes and the reaction progress was monitored by TLC. Upon completion of the reaction, 1500 g of ice-water mixture was slowly added to quench the reaction and cooled to room temperature. The precipitate was collected by filtration, washed with water and dried to give a light yellow solid product. Upon drying, 51.3 g of ethyl 7-chloro-1H-indole-2-carboxylate was obtained in 85% yield.
References
[1] Patent: CN104402795, 2017, B. Location in patent: Paragraph 0060; 0062
Ethyl 7-chloroindole-2-carboxylate Preparation Products And Raw materials
Ethyl 7-chloroindole-2-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 17389186172 | 1077@dideu.com | China | 3797 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from Ethyl 7-chloroindole-2-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-12 | Ethyl 7-chloroindole-2-carboxylate
43142-64-9
|
$1.00-22.00 | 1KG | 99% | 100000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- Ethyl 7-chloroindole-2-carboxylate
43142-64-9
- $1.00-22.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
