ALPHA-ENDORPHIN
- CAS No.
- 59004-96-5
- Chemical Name:
- ALPHA-ENDORPHIN
- Synonyms
- LPH(61-76);a-Endorphin;α-Endorphin;ALPHA-ENDORPHIN;YGGFMTSEKSQTPLVT;ENDORPHIN, ALPHA-;A-ENDORPHIN HUMAN;α-endorphin human;α-Endorphin human;β-Lipotropin 61-76
- CBNumber:
- CB7261017
- Molecular Formula:
- C77H120N18O26S
- Molecular Weight:
- 1745.95
- MDL Number:
- MFCD00076381
- MOL File:
- 59004-96-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 2076.032±65.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.349±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| RTECS | JZ2270000 |
| storage temp. | −20°C |
| solubility | ≥174.5 mg/mL in DMSO; insoluble in EtOH; ≥52.7 mg/mL in H2O |
| form | White powder |
| pka | 3.237±0.10(predicted) |
| Sequence | Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr |
| Stability | Hygroscopic |
ALPHA-ENDORPHIN price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 24958 | α-Endorphin (human, mouse, rat, porcine, bovine, ovine) ≥95% | 59004-96-5 | 1mg | $96 | 2026-04-30 | Buy |
| Biosynth | PEN-4055-V | Alpha-Endorphin | 59004-96-5 | 0.5mg | $411.49 | 2026-06-04 | Buy |
| Biosynth | FE108746 | Alpha-Endorphin | 59004-96-5 | 2000ug | $900 | 2026-06-04 | Buy |
| Biosynth | FE108746 | Alpha-Endorphin | 59004-96-5 | 1000ug | $900 | 2026-06-04 | Buy |
| Biosynth | FE108746 | Alpha-Endorphin | 59004-96-5 | 500ug | $900 | 2026-06-04 | Buy |
ALPHA-ENDORPHIN Chemical Properties, Uses, Production
Uses
An opioid peptide and substrate for transglutaminase
Biological Activity
endorphins are endogenous opioid peptides that function as neurotransmitters(1). they are produced by the pituitary gland and the hypothalamus in vertebrates during exercise, excitement, pain, consumption of spicy food, love and orgasm, and they resemble the opiates in their abilities to produce analgesia and a feeling of well-being.the term implies a pharmacological activity (analogous to the activity of the corticosteroid category of biochemicals) as opposed to a specific chemical formulation. it consists of two parts: endo- and -orphin; these are short forms of the words endogenous and morphine(2), beta-endorphin (β-endorphin) is released into blood from the pituitary gland and into the spinal cord and brain from hypothalamic neurons. the β-endorphin that is released into the blood cannot enter the brain in large quantities because of the blood–brain barrier, so the physiological importance of the β-endorphin that can be measured in the blood is far from clear. β-endorphin is a cleavage product of pro-opiomelanocortin (pomc), which is also the precursor hormone for adrenocorticotrophic hormone (acth). the behavioural effects of β-endorphin are exerted by its actions in the brain and spinal cord, and it is presumed that the hypothalamic neurons are the major source of β-endorphin at these sites. in situations where the level of acth is increased (e.g., cushing’s syndrome), the level of endorphins also increases slightly(3).figure1 formula of a-endorphinfigure 2 mechanism of endorphin to inhibit lhrh release
IC 50
μ Opioid Receptor/MOR
References
1. Oswald Steward: Functional neuroscience (2000), page 116.2. Goldstein A, Lowery PJ (September 1975). "Effect of the opiate antagonist naloxone on body temperature in rats". Life Sciences 17 (6): 927–31.3. Simantov R, Snyder S (1976). "Morphine-like peptides in mammalian brain: isolation, structure elucidation, and interactions with the opiate receptor". Proc Natl Acad Sci USA 73 (7): 2515–9.
ALPHA-ENDORPHIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| ApexBio Technology LLC | +1-832-696-8203 | info@apexbt.com | United States | 477 | 60 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Xilong Biochemical Technology Co., Ltd. | 021-52907766-8042 | China | 9928 | 58 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
View Latest Price from ALPHA-ENDORPHIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-21 | alpha-Endorphin acetate | $41.00-103.00 | 98.93% | 10g | TargetMol Chemicals Inc. | ||
 |
2022-10-20 | ALPHA-ENDORPHIN
59004-96-5
|
$60.00 | 1kg | 99% | 10mt | Hebei Binshare New Material Co. Ltd | |
 |
2020-02-19 | ALPHA-ENDORPHIN
59004-96-5
|
$7.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- alpha-Endorphin acetate
- $41.00-103.00
- 98.93%
- TargetMol Chemicals Inc.
-
- ALPHA-ENDORPHIN
59004-96-5
- $60.00
- 99%
- Hebei Binshare New Material Co. Ltd
-
- ALPHA-ENDORPHIN
59004-96-5
- $7.00
- 99%
- Career Henan Chemical Co
