Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile Structure
4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile structure
CAS No.
915086-32-7
Chemical Name:
4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile
Synonyms
Androgen receptor antagonist 9;Thiohydantoin androgen receptor antagonist;4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolid...;4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile;Benzonitrile, 4-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl]-2-(trifluoromethyl)-;4-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
CBNumber:
CB72647488
Molecular Formula:
C19H14F3N3O2S
Molecular Weight:
405.39
MDL Number:
MFCD28978634
MOL File:
915086-32-7.mol
MSDS File:
SDS
Last updated:2026-05-28 05:22:10
Request For Quotation

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile Properties

Boiling point 548.7±60.0 °C(Predicted)
Density 1.52±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 2-8°C(protect from light)
pka 9.01±0.30(Predicted)
form Solid
color White to off-white
InChI InChI=1S/C19H14F3N3O2S/c1-18(2)16(27)24(17(28)25(18)12-5-7-14(26)8-6-12)13-4-3-11(10-23)15(9-13)19(20,21)22/h3-9,26H,1-2H3
InChIKey VIMSHSUYAZHWKM-UHFFFAOYSA-N
SMILES C(#N)C1=CC=C(N2C(=S)N(C3=CC=C(O)C=C3)C(C)(C)C2=O)C=C1C(F)(F)F

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0062641 Androgen receptor antagonist 9 ≥97% 915086-32-7 100mg $12 2026-06-04 Buy
ChemScene CS-0062641 Androgen receptor antagonist 9 ≥97% 915086-32-7 250mg $23 2026-06-04 Buy
ChemScene CS-0062641 Androgen receptor antagonist 9 ≥97% 915086-32-7 1g $48 2026-06-04 Buy
ChemScene CS-0062641 Androgen receptor antagonist 9 ≥97% 915086-32-7 5g $135 2026-06-04 Buy
ChemScene CS-0062641 Androgen receptor antagonist 9 ≥97% 915086-32-7 10g $217 2026-06-04 Buy
Product number Packaging Price Buy
CS-0062641 100mg $12 Buy
CS-0062641 250mg $23 Buy
CS-0062641 1g $48 Buy
CS-0062641 5g $135 Buy
CS-0062641 10g $217 Buy

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile Chemical Properties, Uses, Production

Uses

Androgen receptor antagonist 9 (compound 28) is an antagonist of the androgen receptor[1].

References

[1] Jung ME, et al. Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC). J Med Chem. 2010 Apr 8;53(7):2779-96. DOI:10.1021/jm901488g

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile synthesis

26850-26-0
143782-23-4
915086-32-7
Synthesis of 4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile from Propanenitrile,2-[(4-hydroxyphenyl)amino]-2-methyl- and 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile Preparation Products And Raw materials

Raw materials

Propanenitrile,2-[(4-hydroxyphenyl)amino]-2-methyl- 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile

Preparation Products

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile Suppliers

Global Suppliers ( 54)
Supplier Tel Email Country ProdList Advantage
SanoChem (Chengdu) Tech. Co., Ltd. 28-87999436 02887999436 sales@sano-chem.com China 3792 55
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Synches Co., Ltd. 021-53292253 biz@synches.com China 199 64
AstaTech (Chengdu) Pharma. Co., Ltd. 15928766785 15928766785 wupengcheng@astatech.cn China 1995 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Synteam Biochem CO.,ltd +86-021-58380978 13482386415 info@systeambc.com China 897 50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Jiaxing Rich Biological Technology Co., Ltd. 0573-11111111-1111 18969316891 richmol@163.com China 446 50
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai CR Corporation Limited 13917420128 13062833949 fred.wen@crcorporation.cn China 9769 58
Supplier Advantage
SanoChem (Chengdu) Tech. Co., Ltd. 55
Jia Xing Isenchem Co.,Ltd 66
Synches Co., Ltd. 64
AstaTech (Chengdu) Pharma. Co., Ltd. 55
Bide Pharmatech Ltd. 60
Shanghai Synteam Biochem CO.,ltd 50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 50
Jiaxing Rich Biological Technology Co., Ltd. 50
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai CR Corporation Limited 58

View Latest Price from 4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(3-(4-Hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile pictures 2026-08-25 4-(3-(4-Hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
915086-32-7
 $2.00-6.00 1kg 99% 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile Spectrum

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile(915086-32-7)1HNMR

915086-32-7 (4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile) Related Search:

Enzalutamide carboxylic acid N-desMethyl EnzalutaMide Enzalutamide 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester
Enzalutamide Impurity 1

1of2

4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolidin-1-yl)-2-(trifluoroMethyl)benzonitrile Benzonitrile, 4-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-thioxo-1-imidazolidinyl]-2-(trifluoromethyl)- 4-[3-(4-hydroxyphenyl)-4,4-dimethyl-5-oxo-2-sulfanylideneimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile Thiohydantoin androgen receptor antagonist 4-(3-(4-hydroxyphenyl)-4,4-diMethyl-5-oxo-2-thioxoiMidazolid... Androgen receptor antagonist 9 915086-32-7