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ASPERLIN
- CAS No.
- 30387-51-0
- Chemical Name:
- ASPERLIN
- Synonyms
- D02999;U 13933;ASPERLIN;ASPERLINE;Asperlin (usan);D-galacto-Oct-2-enonic acid, 6,7-anhydro-2,3,8-trideoxy-, δ-lactone, 4-acetate
- CBNumber:
- CB7268793
- Molecular Formula:
- C10H12O5
- Molecular Weight:
- 212.2
- MDL Number:
- MFCD01939372
- MOL File:
- 30387-51-0.mol
Last updated:2025-04-17 18:22:24
Boiling point | 360.4±42.0 °C(Predicted) |
---|---|
Density | 1.28±0.1 g/cm3(Predicted) |
FDA UNII | 8KOW0SA4L3 |
ASPERLIN Chemical Properties,Uses,Production
Uses
Antibacterial; antineoplastic.
in vivo
Asperlin (40-80 mg/kg; p.o.; once daily for 12 weeks) effectively prevents the development of obesity, stimulates energy expenditure and modulates gut microbiota in high-fat diet (HFD)-fed mice[2].
Asperlin (80mg / kg; p.o.; once daily for 12 weeks) remarkably suppresses atherosclerotic plaque formation in the aorta, as revealed by the reduced aortic dilatation and decreased atherosclerotic lesion area in high-fat diet (HFD)-fed ApoE-/- mice[5].
Animal Model: | C57BL/6J mice (8-weeks old, weighing 20-25g) were fed with a high-fat diet (HFD) to induce obesity[2] |
Dosage: | 40, 80 mg/kg |
Administration: | Oral gavage (p.o.), once daily for 12 weeks |
Result: | Showed lower body weight, and food intake was not varied. Reduced the blood levels of total cholesterol (TC), triglycerides (TG) and low-density lipoprotein (LDL-c). Liver TC, TG contents and fat vacuoles were also substantially reversed. Increased energy expenditure and enhanced thermogenic gene (PGC1α, UCP1, CIDEA, CPT1B, FATP1, CYTO-C) expression in adipose tissue. Increased the diversity of the gut microbes. Significantly shifted the structure of the gut microbiota. |
Animal Model: | Male C57BL/6 J and C57BL/6 J ApoE-/- mice (6-8 weeks, weighting 20-25 g)[5] |
Dosage: | 80 mg/kg |
Administration: | Oral gavage (p.o.), once daily for 12 weeks |
Result: | Remarkably suppressed atherosclerotic plaque formation in aorta, reduced the white atherosclerotic lesions, effectively inhibited aortic dilatation in ApoE-/- mice. |
ASPERLIN Preparation Products And Raw materials
Raw materials
Preparation Products
ASPERLIN Suppliers
Global( 8)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
Zhejiang Huida Biotech Co., LTD | 0571-89903882 15990081639 | sunshixuan@huidabiotech.com | China | 3644 | 58 |
TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | sales@tcisct.com | China | 31121 | 58 |
Zhejiang Huida Biotech Co., LTD | 0571-0571-89903882 15990081639 | sunshixuan@huidabiotech.com | China | 3705 | 58 |
Supplier | Advantage |
---|---|
BOC Sciences | 65 |
Zhejiang Huida Biotech Co., LTD | 58 |
TCI (Shanghai) Chemical Trading Co., Ltd. | 58 |
Zhejiang Huida Biotech Co., LTD | 58 |
30387-51-0(ASPERLIN)Related Search:
U 13933
ASPERLIN
ASPERLINE
Asperlin (usan)
D02999
D-galacto-Oct-2-enonic acid, 6,7-anhydro-2,3,8-trideoxy-, δ-lactone, 4-acetate
30387-51-0
Antibiotic