Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3-Chloro-5-fluoronitrobenzene

3-Chloro-5-fluoronitrobenzene

3-Chloro-5-fluoronitrobenzene Structure
3-Chloro-5-fluoronitrobenzene structure
CAS No.
4815-64-9
Chemical Name:
3-Chloro-5-fluoronitrobenzene
Synonyms
3-Chloro-5-fluoronitrobenzene;Benzene, 1-chloro-3-fluoro-5-nitro-
CBNumber:
CB72705764
Molecular Formula:
C6H3ClFNO2
Molecular Weight:
175.54
MDL Number:
MFCD11973918
MOL File:
4815-64-9.mol
Last updated:2026-05-28 05:46:11
Request For Quotation

3-Chloro-5-fluoronitrobenzene Properties

Boiling point 198-200 °C(Press: 762 Torr)
Density 1.494±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
Appearance Colorless to light yellow Liquid
InChI InChI=1S/C6H3ClFNO2/c7-4-1-5(8)3-6(2-4)9(10)11/h1-3H
InChIKey TZAGKOKYKROSOW-UHFFFAOYSA-N
SMILES C1(Cl)=CC([N+]([O-])=O)=CC(F)=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2904990090

3-Chloro-5-fluoronitrobenzene price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC201258 1-Chloro-3-fluoro-5-nitrobenzene 99% 4815-64-9 1g $25 2026-06-04 Buy
Apolloscientific PC201258 1-Chloro-3-fluoro-5-nitrobenzene 99% 4815-64-9 5g $102 2026-06-04 Buy
Apolloscientific PC201258 1-Chloro-3-fluoro-5-nitrobenzene 99% 4815-64-9 25g $358 2026-06-04 Buy
Activate Scientific AS48160 1-Chloro-3-fluoro-5-nitrobenzene 98% 4815-64-9 1g $37 2026-06-04 Buy
Activate Scientific AS48160 1-Chloro-3-fluoro-5-nitrobenzene 98% 4815-64-9 5g $131 2026-06-04 Buy
Product number Packaging Price Buy
PC201258 1g $25 Buy
PC201258 5g $102 Buy
PC201258 25g $358 Buy
AS48160 1g $37 Buy
AS48160 5g $131 Buy

3-Chloro-5-fluoronitrobenzene Chemical Properties, Uses, Production

Uses

1-Chloro-3-fluoro-5-nitrobenzene

Synthesis

3-CHLORO-5-FLUOROANILINE

4863-91-6

3-Chloro-5-fluoronitrobenzene

4815-64-9

General procedure for the synthesis of 1-chloro-3-fluoro-5-nitrobenzene from 3-chloro-5-fluoroaniline: (a) Sodium perborate tetrahydrate (7.69 g, 50.0 mmol) was suspended in 30 mL of acetic acid and the suspension was heated to 55 °C. 3-Chloro-5-fluoroaniline (1.46 g, 10 mmol) was dissolved in 20 mL of acetic acid and slowly added to the above suspension over a period of 1 hour. The reaction mixture was stirred at 55 °C for 1 h and then cooled to room temperature. To the reaction mixture was added 300 mL of tert-butyl methyl ether (TBME) and the solid was separated by filtration. The organic layer was washed sequentially with saturated saline, 20 mL of aqueous sodium thiosulfate and saturated saline. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to obtain the crude product. The crude product was purified by silica gel column chromatography (40 g SiO; eluent: cyclohexane) to afford 1-chloro-3-fluoro-5-nitrobenzene as a solid (320 mg, 18% yield). 1H-NMR (400 MHz; DMSO-d6): δ 8.20 (s, 1H), 8.18 (d, 1H), 8.07 (d, 1H).

References

[1] Patent: WO2013/61305, 2013, A1. Location in patent: Page/Page column 46

3-Chloro-5-fluoronitrobenzene synthesis

4863-91-6
4815-64-9
Synthesis of 3-Chloro-5-fluoronitrobenzene from 3-Chloro-5-fluoroaniline

3-Chloro-5-fluoronitrobenzene Preparation Products And Raw materials

Raw materials

3-Chloro-5-fluoroaniline Sodium perborate tetrahydrate Acetic acid

Preparation Products

3-Chloro-5-fluoronitrobenzene Suppliers

Global Suppliers ( 57)
Supplier Tel Email Country ProdList Advantage
changzhou ansciep chemical co., ltd. 0519-86305871 13961213398; tina@ansciepchem.com China 1600 58
Tianjin Jinyuda Chemical Co., Ltd. 022-58013646 13011382049 sales@jinyudachem.com China 1976 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
MINKESH (SHANGHAI) CO., LTD. +86-021-20980300 +86-13167252998 sales@minkesh.com China 92 55
Xinyanhe Pharmatech Co.,Ltd 0519-85252752 15366845260 taihuaren@vip.163.com China 1031 58
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4534 58
Tianjin Anhao Biological Technology Co., Ltd. sales@ahpharmatech.com China 5734 55
Changzhou Tianrui Pharmaceutical Technology Co., Ltd. 0519-85386832 13382812559 sales@cztrchem.com China 1211 56
Nanjing Chalf-Pharm Technology Co., Ltd. 025-57018978 18251899859 sales@chalf-pharm.com China 5855 50
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
changzhou ansciep chemical co., ltd. 58
Tianjin Jinyuda Chemical Co., Ltd. 55
Bide Pharmatech Ltd. 60
MINKESH (SHANGHAI) CO., LTD. 55
Xinyanhe Pharmatech Co.,Ltd 58
Mashilabs (Shanghai) Co.,Ltd. 58
Tianjin Anhao Biological Technology Co., Ltd. 55
Changzhou Tianrui Pharmaceutical Technology Co., Ltd. 56
Nanjing Chalf-Pharm Technology Co., Ltd. 50
Amadis Chemical Company Limited 58

View Latest Price from 3-Chloro-5-fluoronitrobenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Chloro-5-fluoronitrobenzene pictures 2026-08-07 3-Chloro-5-fluoronitrobenzene
4815-64-9
 $1.00-1.50 1KG 99% 100000KG Shaanxi Dideu Medichem Co. Ltd

3-Chloro-5-fluoronitrobenzene Spectrum

3-Chloro-5-fluoronitrobenzene(4815-64-9)1HNMR3-Chloro-5-fluoronitrobenzene(4815-64-9)FT-IR

4815-64-9 (3-Chloro-5-fluoronitrobenzene) Related Search:

3-Chloro-5-fluoroaniline 3-Chloro-4,5-difluoronitrobenzene 4-Chloro-3-fluoronitrobenzene 5-Chloro-1,2-difluoro-3-nitrobenzene 1-Chloro-2,5-difluoro-3-nitrobenzene
3-Chloro-4-fluoronitrobenzene

1of2

3-Chloro-5-fluoronitrobenzene Benzene, 1-chloro-3-fluoro-5-nitro- 4815-64-9