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phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Structure
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate structure
CAS No.
379270-35-6
Chemical Name:
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Synonyms
Monophenylester;TAF Impurity 3;GS7340 impurity1;GS7340 intermediate 1;Tenofovir Impurity 30;Tenofovir alafenamide-4;Tenofovir Alafenamide acid;Tenofovir Related Compound 2;Tenofovir Alafenamide Impurity 28;Tenofovir Alafenamide Impurity 18
CBNumber:
CB72729612
Molecular Formula:
C15H18N5O4P
Molecular Weight:
363.31
MDL Number:
MFCD28386144
MOL File:
379270-35-6.mol
Last updated:2026-05-12 09:20:59
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phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Properties

Melting point 237-239°C
Boiling point 610.1±65.0 °C(Predicted)
Density 1.53±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated)
pka 2.09±0.10(Predicted)
form Solid
color White to Off-White
InChI InChI=1S/C15H18N5O4P/c1-11(7-20-9-19-13-14(16)17-8-18-15(13)20)23-10-25(21,22)24-12-5-3-2-4-6-12/h2-6,8-9,11H,7,10H2,1H3,(H,21,22)(H2,16,17,18)/t11-/m1/s1
InChIKey ITAMCOCNZJPJDF-LLVKDONJSA-N
SMILES C(P(=O)(O)OC1=CC=CC=C1)O[C@H](C)CN1C2C(N=C1)=C(N)N=CN=2
FDA UNII 6F4V6F8MSR

SAFETY

Risk and Safety Statements

REACH Registrations Active

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00CKJ9 Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97% 379270-35-6 250mg $12 2026-05-28 Buy
aablocks AA00CKJ9 Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97% 379270-35-6 1g $18 2026-05-28 Buy
aablocks AA00CKJ9 Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97% 379270-35-6 5g $52 2026-05-28 Buy
ACHEMBLOCK Y219171 [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester 97.00% 379270-35-6 25G $250 2026-05-27 Buy
ACHEMBLOCK Y219171 [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester 97.00% 379270-35-6 100G $835 2026-05-27 Buy
Product number Packaging Price Buy
AA00CKJ9 250mg $12 Buy
AA00CKJ9 1g $18 Buy
AA00CKJ9 5g $52 Buy
Y219171 25G $250 Buy
Y219171 100G $835 Buy

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Chemical Properties, Uses, Production

Appearance

White powder

Uses

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.

Application

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate synthesis

147127-20-6
108-95-2
379270-35-6
Synthesis of phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate from Tenofovir and Phenol

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Preparation Products And Raw materials

Raw materials

Diphenyliodium fluoride Diphenyliodonium hexafluoroarsenate Tenofovir Diphenyliodonium bromide Diphenyl phosphite
Diphenyliodonium trifluoromethanesulfonate Phenol Triphenyl phosphite

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Preparation Products

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Suppliers

Global Suppliers ( 210)
Supplier Tel Email Country ProdList Advantage
Zhuhai Yourun Co., Ltd. 0756-6811852 15876689832 zhyrpharm_sales03@126.com China 290 55
Jinan chenghui-shuangda chemical co.,ltd. 13256107535 mahaiyan1123@126.com China 118 58
Huangshi Fuertai Pharmaceutical Tech Co., Ltd. 3293168 13995956430 fuertaixia@foxmail.com China 34 58
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7909 65
AF Biochem Co., Ltd. +86-028-60911900 13540204019 sales@afbiochem.com China 479 57
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7993 58
Shanghai Twisun Bio-pharm Co.,Ltd +86-21-33282107 China 107 60
Ningbo Taikang Chemical Co., Ltd. 0574-87365517 18074210286 sales@taikangchem.com China 294 58
Supplier Advantage
Zhuhai Yourun Co., Ltd. 55
Jinan chenghui-shuangda chemical co.,ltd. 58
Huangshi Fuertai Pharmaceutical Tech Co., Ltd. 58
Adamas Reagent, Ltd. 59
Daicel Chiral Technologies (China)CO.,LTD 65
AF Biochem Co., Ltd. 57
T&W GROUP 58
TargetMol Chemicals Inc. 58
Shanghai Twisun Bio-pharm Co.,Ltd 60
Ningbo Taikang Chemical Co., Ltd. 58

View Latest Price from phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate pictures 2026-09-17 Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate
379270-35-6
 $23.00 1KG >=99% 20mt/year Jinan Finer Chemical Co., Ltd
Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate pictures 2026-09-17 Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate
379270-35-6
 $80.00-416.00 25g 0.97 25kg Shanghai UCHEM Inc.
Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate pictures 2026-09-03 Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate
379270-35-6
 1kg 98% by HPLC 100kg/month Zison Pharmaceutical (Shandong) Co., Ltd.

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Spectrum

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate(379270-35-6)1HNMR

379270-35-6 (phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate) Related Search:

6N-HydroxyMethyl Tenofovir Disoproxil Tenofovir Related Compound 14 D-Alanine Isopropyl Ester HCl Tenofovir Alafenamide PMPA Impurity Tenofovir disoproxil
Tenofovir isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Alafenamide Impurity 6 Tenofovir Related Compound 5 Tenofovir Alafenamide Impurity 30
Tenofovir Related Compound 4 diisopropyl 2,2'-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(azanediyl))(2S,2'S)-dipropionate compound with methane (1:1) Tenofovir Related Compound 6 isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy) phosphoryl)-D-alaninate isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate
Tenofovir Related Compound 1 isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Alafenamide

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[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester Tenofovir Related Compound 2 phenyl ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate GS7340 impurity1 GS7340 intermediate 1 phenylydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) phosphonate phenyl hydrogen (R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Phenyl hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenylester Tenofovir alafenamide-4 [2-(6-Amino-purin-9- yl)-1-methyl-ethoxy methyl]-phosphonic acid monophenyl ester The intermediate of Tenofovir Alafenamide Tenofovir alafenamide Intermediate Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenyl ester (9CI) Tenofovir Impurity 30 Tenofovir alafenamide Intermediate 1 Monophenylester Tenofovir Alafenamide Impurity 28 TAF Impurity 3 Tenofovir Monophenyl Ester Impurity Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methyleth... (1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-phenoxy-phosphinic acid 9-[(R)-2- (phenylphosphonomethoxy) propyl]adenine (PPMPA) Tenofovir Alafenamide Fumarate N-3 Tenofovir Alafenamide acid (S)-propyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate Tenofovir Alafenamide Impurity 18 phenyl hydrogen ({[[](2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate Phenyl Hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate (Tenofovir Impurity) Phenyl hydrogen ((((R)-1-(6-aino-9H-purin-9-yl)propan-2-yl)oxy)ethyl)phosphonate 379270-35-6 C15H18N5O4P Intermediate 379270-35-6