ChemicalBook >> CAS DataBase List >>phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate structure

CAS No.: 379270-35-6

Chemical Name:: phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

Synonyms: Monophenylester;TAF Impurity 3;GS7340 impurity1;GS7340 intermediate 1;Tenofovir Impurity 30;Tenofovir alafenamide-4;Tenofovir Alafenamide acid;Tenofovir Related Compound 2;Tenofovir Alafenamide Impurity 28;Tenofovir Alafenamide Impurity 18

CBNumber:: CB72729612

Molecular Formula:: C15H18N5O4P

Molecular Weight:: 363.31

MDL Number:: MFCD28386144

MOL File:: 379270-35-6.mol

Last updated:2026-05-12 09:20:59

Product description	Number	Pack Size	Price
Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97%	AA00CKJ9	250mg	$12
Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97%	AA00CKJ9	1g	$18
Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97%	AA00CKJ9	5g	$52
[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester 97.00%	Y219171	25G	$250
[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester 97.00%	Y219171	100G	$835
More product size

Request For Quotation

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Properties

Melting point	237-239°C
Boiling point	610.1±65.0 °C(Predicted)
Density	1.53±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated)
pka	2.09±0.10(Predicted)
form	Solid
color	White to Off-White
InChI	InChI=1S/C15H18N5O4P/c1-11(7-20-9-19-13-14(16)17-8-18-15(13)20)23-10-25(21,22)24-12-5-3-2-4-6-12/h2-6,8-9,11H,7,10H2,1H3,(H,21,22)(H2,16,17,18)/t11-/m1/s1
InChIKey	ITAMCOCNZJPJDF-LLVKDONJSA-N
SMILES	C(P(=O)(O)OC1=CC=CC=C1)O[C@H](C)CN1C2C(N=C1)=C(N)N=CN=2
FDA UNII	6F4V6F8MSR

SAFETY

Risk and Safety Statements

REACH Registrations	Active

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA00CKJ9	Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97%	379270-35-6	250mg	$12	2026-05-28	Buy
aablocks	AA00CKJ9	Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97%	379270-35-6	1g	$18	2026-05-28	Buy
aablocks	AA00CKJ9	Phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate 97%	379270-35-6	5g	$52	2026-05-28	Buy
ACHEMBLOCK	Y219171	[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester 97.00%	379270-35-6	25G	$250	2026-05-27	Buy
ACHEMBLOCK	Y219171	[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester 97.00%	379270-35-6	100G	$835	2026-05-27	Buy

Product number	Packaging	Price	Buy
AA00CKJ9	250mg	$12	Buy
AA00CKJ9	1g	$18	Buy
AA00CKJ9	5g	$52	Buy
Y219171	25G	$250	Buy
Y219171	100G	$835	Buy

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Chemical Properties,Uses,Production

Appearance

White powder

Uses

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.

Application

[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate synthesis

Synthesis of phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate from Tenofovir and Phenol

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Preparation Products And Raw materials

Raw materials

DIPHENYLIODIUM FLUORIDE DIPHENYLIODONIUM HEXAFLUOROARSENATE Tenofovir DIPHENYLIODONIUM BROMIDE DIPHENYL PHOSPHITE

DIPHENYLIODONIUM TRIFLUOROMETHANESULFONATE Phenol Triphenyl phosphite

1of2

Preparation Products

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Suppliers

Global( 207)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8742	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29640	60
Nanjing Gold Pharmaceutical Technology Co. Ltd.	025-84209270 15906146951		CHINA	115	55
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
HaBo Hong Kong Co., Limited.	+86-25-18512596065	info@habotech.com	CHINA	933	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2950	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58

Supplier	Advantage
Shanghai UCHEM Inc.	58
Capot Chemical Co.,Ltd.	60
Nanjing Gold Pharmaceutical Technology Co. Ltd.	55
Beijing Cooperate Pharmaceutical Co.,Ltd	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
HaBo Hong Kong Co., Limited.	58
Jinan Finer Chemical Co., Ltd	58
Standardpharm Co. Ltd.	58

View Lastest Price from phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-29	Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate 379270-35-6	$80.00-416.00	25g	0.97	25kg	Shanghai UCHEM Inc.
2026-05-21	Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate 379270-35-6	$23.00	1KG	>=99%	20mt/year	Jinan Finer Chemical Co., Ltd
2025-12-19	Tenofovir Disoproxil Impurity 8 379270-35-6		10mg	90%+	10g	Guangzhou PI PI BIOTECH INC

Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate
379270-35-6
$80.00-416.00
0.97
Shanghai UCHEM Inc.

Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate
379270-35-6
$23.00
>=99%
Jinan Finer Chemical Co., Ltd

Tenofovir Disoproxil Impurity 8
379270-35-6
90%+
Guangzhou PI PI BIOTECH INC

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Spectrum

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate(379270-35-6)¹HNMR

379270-35-6(phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate)Related Search:

6N-HydroxyMethyl Tenofovir Disoproxil Tenofovir Related Compound 14 D-Alanine Isopropyl Ester HCl Tenofovir Alafenamide PMPA Impurity Tenofovir disoproxil

Tenofovir isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Alafenamide Impurity 6 Tenofovir Related Compound 5 Tenofovir Alafenamide Impurity 30

Tenofovir Related Compound 4 diisopropyl 2,2'-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(azanediyl))(2S,2'S)-dipropionate compound with methane (1:1) Tenofovir Related Compound 6 isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy) phosphoryl)-D-alaninate isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate

Tenofovir Related Compound 1 isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Alafenamide

1of4

[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester Tenofovir Related Compound 2 phenyl ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate GS7340 impurity1 GS7340 intermediate 1 phenylydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) phosphonate phenyl hydrogen (R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Phenyl hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenylester Tenofovir alafenamide-4 [2-(6-Amino-purin-9- yl)-1-methyl-ethoxy methyl]-phosphonic acid monophenyl ester The intermediate of Tenofovir Alafenamide Tenofovir alafenamide Intermediate Phosphonic acid, [[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, monophenyl ester (9CI) Tenofovir Impurity 30 Tenofovir alafenamide Intermediate 1 Monophenylester Tenofovir Alafenamide Impurity 28 TAF Impurity 3 Tenofovir Monophenyl Ester Impurity Phosphonic acid,[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methyleth... (1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-phenoxy-phosphinic acid 9-[(R)-2- (phenylphosphonomethoxy) propyl]adenine (PPMPA) Tenofovir Alafenamide Fumarate N-3 Tenofovir Alafenamide acid (S)-propyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate Tenofovir Alafenamide Impurity 18 phenyl hydrogen ({[[](2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate Phenyl Hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate (Tenofovir Impurity) 379270-35-6 C15H18N5O4P Intermediate 379270-35-6