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phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

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phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Suppliers list
Company Name: NANJING YINGWEN BIOTECHNOLOGY CO LTD
Tel: +86-13382787392
Email: sales@aeechem.com
Products Intro: CAS:379270-35-6
Purity:98%
Company Name: Shanghai UCHEM Inc.
Tel: +86-18930848214 +86-021-56762820
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Products Intro: Product Name:Phenyl hydrogen [(R)-1-(6-amino-9H-purin-9-yl)propan-2-yloxy]methylphosphonate
CAS:379270-35-6
Purity:0.97 Package:25g;80USD|100g;222USD|250g;416USD
Company Name: Capot Chemical Co.,Ltd.
Tel: +86-（0）57185586718 +86-13336195806
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Products Intro: Product Name:Tenofovir alafenamide Intermediate 1
CAS:379270-35-6
Purity:NLT 98% Package:1G;1KG;100KG
Company Name: Nanjing Gold Pharmaceutical Technology Co. Ltd.
Tel: 025-84209270 15906146951
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Products Intro: Product Name:[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester
CAS:379270-35-6
Purity:99% Package:1000KG;;100KG;10KG;5KG;1KG
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd
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Products Intro: Product Name:[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester
CAS:379270-35-6
Purity:98%99% Package:100G;1KG;5KG;10KG;25KG;50KG;100KG

phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate manufacturers
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Basic information
Appearance
Product Name:phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Synonyms:[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester;Tenofovir Related Compound 2;phenyl ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate;GS7340 impurity1;GS7340 intermediate 1;phenylydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) phosphonate;phenyl hydrogen (R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate;Phenyl hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate
CAS:379270-35-6
MF:C15H18N5O4P
MW:363.31
EINECS:807-851-4
Product Categories:Intermediate;379270-35-6
Mol File:379270-35-6.mol
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Structure
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Chemical Properties
Melting point 237-239°C
Boiling point 610.1±65.0 °C(Predicted)
density 1.53±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated)
pka2.09±0.10(Predicted)
form Solid
color White to Off-White
InChIInChI=1S/C15H18N5O4P/c1-11(7-20-9-19-13-14(16)17-8-18-15(13)20)23-10-25(21,22)24-12-5-3-2-4-6-12/h2-6,8-9,11H,7,10H2,1H3,(H,21,22)(H2,16,17,18)/t11-/m1/s1
InChIKeyITAMCOCNZJPJDF-LLVKDONJSA-N
SMILESC(P(=O)(O)OC1=CC=CC=C1)O[C@H](C)CN1C2C(N=C1)=C(N)N=CN=2
Safety Information
MSDS Information
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Usage And Synthesis
AppearanceWhite powder
Uses[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.
Application[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate Preparation Products And Raw materials
Raw materialsDIPHENYLIODIUM FLUORIDE-->DIPHENYLIODONIUM HEXAFLUOROARSENATE-->Tenofovir-->DIPHENYLIODONIUM BROMIDE-->DIPHENYL PHOSPHITE-->DIPHENYLIODONIUM TRIFLUOROMETHANESULFONATE-->Phenol-->Triphenyl phosphite
Tag:phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate(379270-35-6) Related Product Information
6N-HydroxyMethyl Tenofovir Disoproxil Tenofovir Related Compound 14 D-Alanine Isopropyl Ester HCl Tenofovir Alafenamide PMPA Impurity Tenofovir disoproxil Tenofovir isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Alafenamide Impurity 6 Tenofovir Related Compound 5 Tenofovir Alafenamide Impurity 30 Tenofovir Related Compound 4 diisopropyl 2,2'-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(azanediyl))(2S,2'S)-dipropionate compound with methane (1:1) Tenofovir Related Compound 6 isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy) phosphoryl)-D-alaninate isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Related Compound 1 isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Alafenamide