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THK-5107

THK-5107 Structure
THK-5107 structure
CAS No.
1374107-54-6
Chemical Name:
THK-5107
Synonyms
THK-5117;THK-5107;6-(3-Fluoro-2-hydroxypropoxy)-2-(4-methylaminophenyl)quinoline;1-fluoro-3-[2-[4-(methylamino)phenyl]quinolin-6-yl]oxypropan-2-ol;2-Propanol, 1-fluoro-3-[[2-[4-(methylamino)phenyl]-6-quinolinyl]oxy]-
CBNumber:
CB73049241
Molecular Formula:
C19H19FN2O2
Molecular Weight:
326.36
MDL Number:
MFCD29767871
MOL File:
1374107-54-6.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08
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THK-5107 Properties

Boiling point 548.8±50.0 °C(Predicted)
Density 1.246±0.06 g/cm3(Predicted)
pka 12.84±0.20(Predicted)
form Solid
color Off-white to light yellow

THK-5107 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0020952 THK-5117 98.52% 1374107-54-6 5mg $720 2026-06-04 Buy
ChemScene CS-0020952 THK-5117 98.52% 1374107-54-6 10mg $1192 2026-06-04 Buy
ChemScene CS-0020952 THK-5117 98.52% 1374107-54-6 25mg $2654 2026-06-04 Buy
ChemScene CS-0020952 THK-5117 98.52% 1374107-54-6 50mg $3737 2026-06-04 Buy
aablocks AA009IA5 THK-5107 >98% 1374107-54-6 5mg $774 2026-05-28 Buy
Product number Packaging Price Buy
CS-0020952 5mg $720 Buy
CS-0020952 10mg $1192 Buy
CS-0020952 25mg $2654 Buy
CS-0020952 50mg $3737 Buy
AA009IA5 5mg $774 Buy

THK-5107 Chemical Properties, Uses, Production

Uses

THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5117 hasthepotential to act as a tau imaging PET probe[1].

References

[1] Nobuyuki Okamura, et al. Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease. J Nucl Med. 2013 Aug;54(8):1420-7. DOI:10.2967/jnumed.112.117341

THK-5107 Preparation Products And Raw materials

Raw materials

Preparation Products

THK-5107 Suppliers

Global Suppliers ( 9)
Supplier Tel Email Country ProdList Advantage
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9331 58
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 027-65388397 18164111589 3321478047@qq.com China 2002 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Shanghai Biopharmaleader Co., Ltd. +86 18721201413 sales@biopharmaleader.com China 1711 58
Finetech Industry Limited +86-27-8746-5837 +86-18627785180 info@finetechnology-ind.com China 9533 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 ivan@atkchemical.com China 32997 60
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Shanghai Boyle Chemical Co., Ltd. 55
Finetech Industry Limited 58
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 55
Amadis Chemical Company Limited 58
Shanghai Biopharmaleader Co., Ltd. 58
Finetech Industry Limited 58
TargetMol Chemicals Inc. 58
ATK CHEMICAL COMPANY LIMITED 60
TargetMol Chemicals Inc. 58

View Latest Price from THK-5107 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
THK-5117 pictures 2026-07-15 THK-5117
1374107-54-6
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • THK-5117 pictures
  • THK-5117
    1374107-54-6
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.

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THK-5107 6-(3-Fluoro-2-hydroxypropoxy)-2-(4-methylaminophenyl)quinoline 2-Propanol, 1-fluoro-3-[[2-[4-(methylamino)phenyl]-6-quinolinyl]oxy]- 1-fluoro-3-[2-[4-(methylamino)phenyl]quinolin-6-yl]oxypropan-2-ol THK-5117 1374107-54-6