7-Bromo-2,2-dimethylchroman-4-one
- CAS No.
- 130200-01-0
- Chemical Name:
- 7-Bromo-2,2-dimethylchroman-4-one
- Synonyms
- 7-Bromo-2,2-dimethylchroman-4-one;7-Bromo-2,2-dimethyl-3H-chromen-4-one;7-BROMO-2,3-DIHYDRO-2,2-DIMETHYLCHROMEN-4-ONE;4H-1-Benzopyran-4-one, 7-bromo-2,3-dihydro-2,2-dimethyl-
- CBNumber:
- CB73070722
- Molecular Formula:
- C11H11BrO2
- Molecular Weight:
- 255.11
- MDL Number:
- MFCD13190381
- MOL File:
- 130200-01-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
7-Bromo-2,2-dimethylchroman-4-one price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FFA20001 | 7-Bromo-2,2-dimethylchroman-4-one | 130200-01-0 | 5g | $413 | 2026-06-04 | Buy |
| Matrix Scientific | 302008 | 7-Bromo-2,2-dimethylchroman-4-one | 130200-01-0 | 250.00mg | $50 | 2026-05-19 | Buy |
| Matrix Scientific | 302008 | 7-Bromo-2,2-dimethylchroman-4-one | 130200-01-0 | 1.00g | $63 | 2026-05-19 | Buy |
| Matrix Scientific | 302008 | 7-Bromo-2,2-dimethylchroman-4-one | 130200-01-0 | 5.00g | $276 | 2026-05-19 | Buy |
| Synthonix | B54449 | 7-Bromo-2,2-dimethylchroman-4-one 97% | 130200-01-0 | 100mg | $46 | 2026-05-06 | Buy |
7-Bromo-2,2-dimethylchroman-4-one Chemical Properties,Uses,Production
Synthesis
591-20-8
130200-01-0
General procedure for the synthesis of 7-bromo-2,2-dimethylchromen-4-one from m-bromophenol: About 15 g of polyphosphoric acid was added to a mixture of 3,3-dimethylacrylic acid (5.0 g, 54.9 mmol) and 3-bromophenol (10.4 g, 60.4 mmol). The mixture was stirred and reacted at 95 °C for 4 h under argon protection. Upon completion of the reaction, the reaction slurry was cooled to 0 °C with an ice bath, dissolved in 200 mL of ice water and subsequently extracted with ether (3 x 100 mL). The organic phase was separated and washed sequentially with 5N KOH aqueous solution (50 mL) and saturated saline (50 mL). The extract was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: 5% ethyl acetate/hexane) to afford 7-bromo-2,2-dimethylchromen-4-one (2.80 g, 22% yield) as a brown solid.1H-NMR (300 MHz, CDCl3) data were as follows: δ 1.45 (s, 6H), 2.71 (s, 2H), 7.13 (m, 2H), and 7.72 (d, 1H, J = 8.3 Hz).
References
[1] Patent: US6403638, 2002, B1
7-Bromo-2,2-dimethylchroman-4-one Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan Yuehe Bio-Pharmaceutical Co.,Ltd | 028-82729560 17365561851 | tangzhichen@yuehepharm.com | China | 212 | 58 |
| Shanghai YuanQi Biotechnology Co., Ltd. | +86-2332782371 +86-18120098618 | sales@adobechem.com | China | 1250 | 50 |
| Changzhou Hopschain Chemical Co.,Ltd. | 85528066 13775048983 | sales@hopschem.com | China | 31548 | 55 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Henan Alfachem Co.,Ltd. | 0371-55051623 18137891487 | 3983243027@qq.com | China | 9965 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9733 | 58 |
| Advanced chemblocks inc | 650-6922368 650-6922368;650-6922368 | sales@achemblock.com | China | 2988 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
