ChemicalBook >> CAS DataBase List >>RX-518
RX-518
- CAS No.
- 1660963-42-7
- Chemical Name:
- RX-518
- Synonyms
- CK-101;Olafertinib;CK101;CK 101;RX-518;CS-2481;EGFR-IN-3;RX518(CK-101);EGFR inhibitor 3;Olafertinib (RX-518)
- CBNumber:
- CB73119786
- Molecular Formula:
- C29H28F2N6O2
- Molecular Weight:
- 530.57
- MDL Number:
- MFCD30345533
- MOL File:
- 1660963-42-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-27 17:00:41
| Density | 1.350±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO : 125 mg/mL (235.60 mM);Water : < 0.1 mg/mL (insoluble) |
| form | Solid |
| pka | 13.28±0.70(Predicted) |
| color | Light yellow to yellow |
| FDA UNII | 708TLB8J3Y |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
RX-518 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 40922 | RX-518 ≥98% | 1660963-42-7 | 5mg | $94 | 2026-04-30 | Buy |
| Cayman Chemical | 40922 | RX-518 ≥98% | 1660963-42-7 | 10mg | $179 | 2026-04-30 | Buy |
| Cayman Chemical | 40922 | RX-518 ≥98% | 1660963-42-7 | 50mg | $468 | 2026-04-30 | Buy |
| Cayman Chemical | 40922 | RX-518 ≥98% | 1660963-42-7 | 100mg | $655 | 2026-04-30 | Buy |
| Biosynth | KRC96342 | EGFR-IN-3 | 1660963-42-7 | 50mg | $787 | 2026-06-04 | Buy |
RX-518 Chemical Properties, Uses, Production
Uses
Olafertinib is a third-generation EGFR TKI, with GI50 values of 5 nM (EGFR L858R/T790M), 10 nM (EGFR del19) and 689 nM (EGFR WT), respectively. Olafertinib has the potential for NSCLC research[1].
References
[1] Misako Nagasaka, et al. Beyond osimertinib: The development of 3 rd-generation EGFR Tyrosine Kinase Inhibitors. J Thorac Oncol. 2020 Dec 15;S1556-0864(20)31105-9. DOI:10.1016/j.jtho.2020.11.028
RX-518 Preparation Products And Raw materials
Raw materials
Preparation Products
RX-518 Suppliers
Global Suppliers ( 60)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| Shanghai Shanyuan pharmaceutical technology co., LTD | 021-31761238 13167072949 | 3146446224@qq.com | China | 1420 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2969 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Medi-tech Bioscientific Co., Ltd. | 0519-83246372 13585352506 | China | 1838 | 58 |
View Latest Price from RX-518 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Olafertinib
1660963-42-7
|
$41.00-155.00 | 99.70% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | EGFR-IN-3 | $238.00-948.00 | 98.74% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-04-04 | RX-518
1660963-42-7
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- Olafertinib
1660963-42-7
- $41.00-155.00
- 99.70%
- TargetMol Chemicals Inc.
-
- EGFR-IN-3
- $238.00-948.00
- 98.74%
- TargetMol Chemicals Inc.
-
- RX-518
1660963-42-7
- 98%
- Henan Aochuang Chemical Co.,Ltd.
1660963-42-7 (RX-518) Related Search:
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RX518(CK-101)
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CK101
CK101;CK-101;CK 101;RX518;RX-518;RX 518
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CK-101
Olafertinib
1660963-42-7
C29H28F2N6O2
