TYRPHOSTIN A51
- CAS No.
- 122520-90-5
- Chemical Name:
- TYRPHOSTIN A51
- Synonyms
- AG 183;(Z)-AG-183;TYRPHOSTIN A51;TYRPHOSTIN AG 183;TYRPHOSTIN A51 99+%;Tyrphostin 51(AG-183);TYRPHOSTIN A51 USP/EP/BP;2-AMINO-1,1,3-TRICYANO-4-[3',4',5'-TRIHYDROXYPHENYL]BUTADIENE;2-AMINO-4-(3',4',5'-TRIHYDROXYPHENYL)-1,1,3-TRICYANOBUTA-1,3-DIENE;3-AMINO-2,4-DICYANO-5-(3',4',5'-TRIHYDROXYPHENYL)PENTA-2,4-DIENONITRILE
- CBNumber:
- CB8260628
- Molecular Formula:
- C13H8N4O3
- Molecular Weight:
- 268.23
- MDL Number:
- MFCD00133903
- MOL File:
- 122520-90-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Hazard statements | H302-H312-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P304+P340-P305+P351+P338-P405-P501a |
| WGK Germany | 3 |
| HazardClass | 6.1 |
TYRPHOSTIN A51 price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10010315 | AG-183 ≥98% | 122520-90-5 | 5mg | $44 | 2026-04-30 | Buy |
| Cayman Chemical | 10010315 | AG-183 ≥98% | 122520-90-5 | 10mg | $84 | 2026-04-30 | Buy |
| Cayman Chemical | 10010315 | AG-183 ≥98% | 122520-90-5 | 25mg | $195 | 2026-04-30 | Buy |
| Cayman Chemical | 10010315 | AG-183 ≥98% | 122520-90-5 | 50mg | $344 | 2026-04-30 | Buy |
| ChemScene | CS-0022229 | (Z)-Tyrphostin A51 | 122520-90-5 | 5mg | $102 | 2026-06-04 | Buy |
TYRPHOSTIN A51 Chemical Properties, Uses, Production
Description
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-
Uses
Tyrphostin 51 is a potent inhibitor of EGFRK activity showing mixed competitive inhibition with ATP and substrate1-3..
Definition
ChEBI: 2-amino-4-(3,4,5-trihydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile is a benzenetriol.
References
[1] gazit a, yaish p, gilon c, et al. tyrphostins i: synthesis and biological activity of protein tyrosine kinase inhibitors[j]. journal of medicinal chemistry, 1989, 32(10): 2344-2352.
[2] hubbard s r, till j h. protein tyrosine kinase structure and function[j]. annual review of biochemistry, 2000, 69(1): 373-398.
TYRPHOSTIN A51 Preparation Products And Raw materials
Raw materials
Preparation Products
TYRPHOSTIN A51 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2374 | 58 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29091 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
View Latest Price from TYRPHOSTIN A51 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | (Z)-Tyrphostin A51
122520-90-5
|
$142.00-642.00 | 10g | TargetMol Chemicals Inc. |
-
- (Z)-Tyrphostin A51
122520-90-5
- $142.00-642.00
- TargetMol Chemicals Inc.
