Relamorelin
- CAS No.
- 661472-41-9
- Chemical Name:
- Relamorelin
- Synonyms
- BIM28163;BIM28131;BIM 28163;BIM 28131;BIM-28131;BIM-28163;Relamorelin;4-Piperidinecarboxamide, 3-benzo[b]thien-3-yl-N-(4-piperidinylcarbonyl)-D-alanyl-D-tryptophyl-L-phenylalanyl-4-amino-;4-[[(2S)-2-[[(2R)-2-[[(2R)-3-(1-benzothiophen-3-yl)-2-(piperidine-3-carbonylamino)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]piperidine-4-carboxamide
- CBNumber:
- CB73152219
- Molecular Formula:
- C43H50N8O5S
- Molecular Weight:
- 790.98
- MDL Number:
- MFCD30747945
- MOL File:
- 661472-41-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 1216.171±65.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.361±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| pka | 12.858±0.20(predicted) |
| FDA UNII | BIW199E18V |
Relamorelin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | LBB47241 | Relamorelin | 661472-41-9 | 10mg | $970.3 | 2026-06-04 | Buy |
| Biosynth | LBB47241 | Relamorelin | 661472-41-9 | 25mg | $1582 | 2026-06-04 | Buy |
| Biosynth | LBB47241 | Relamorelin | 661472-41-9 | 50mg | $2531 | 2026-06-04 | Buy |
| Biorbyt Ltd | orb1985365 | Relamorelin 99.26% | 661472-41-9 | 1mg | $540 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1985365 | Relamorelin 99.26% | 661472-41-9 | 5mg | $1190 | 2026-05-06 | Buy |
Relamorelin Chemical Properties, Uses, Production
Uses
Relamorelin (RM-131), a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a Ki of 0.42 nM for GHS-1a receptor. Relamorelin is centrally penetrant. Relamorelin increases growth hormone levels and accelerates gastric emptying. Relamorelin has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research[1][2][3][4].
in vivo
Relamorelin (RM-131; 50-500 nmol/kg/day; s.c.; continuous infusion for 5 days) decreases the loss of body mass and fat mass. Relamorelin (500 nmol/kg/day; continuous infusion for 5 days) increases the food intake and weight gain in rats[1].
RM-131 (250-500nmol/kg; a single s.c.) stimulates acute food intake in wt but not growth hormone secretagogue receptor (GHR) ko mice[2].
| Animal Model: | F344/NTacfBR male rats implanted with tumor[1] |
| Dosage: | 50, 500 nmol/kg/day |
| Administration: | SC; continuous infusion at a rate of 0.5 μL/h for 5 d |
| Result: | Resulted in an increase in food intake (tumor/saline 41.4 g, tumor/BIM-28131 72.5 g) and weight gain (tumor/saline -10.3%, tumor/BIM-28131 +19.5%). |
References
[1] DeBoer MD, et, al. Ghrelin treatment causes increased food intake and retention of lean body mass in a rat model of cancer cachexia. Endocrinology. 2007 Jun;148(6):3004-12. DOI:10.1210/en.2007-0016
[2] Fischer K, et, al. The Pentapeptide RM-131 Promotes Food Intake and Adiposity in Wildtype Mice but Not in Mice Lacking the Ghrelin Receptor. Front Nutr. 2015 Jan 12;1:31. DOI:10.3389/fnut.2014.00031
[3] Zatorski H, et, al. Relamorelin and other ghrelin receptor agonists - future options for gastroparesis, functional dyspepsia and proton pump inhibitors-resistant non-erosive reflux disease. J Physiol Pharmacol. 2017 Dec;68(6):797-805. PMID:29550791
[4] Matthew Heckroth, et al. Nausea and Vomiting in 2021: A Comprehensive Update. J Clin Gastroenterol. 2021 Apr 1;55(4):279-299. DOI:10.1097/MCG.0000000000001485
[5] Victor Chedid, et al. Relamorelin for the treatment of gastrointestinal motility disorders. Expert Opin Investig Drugs. 2017 Oct;26(10):1189-1197. DOI:10.1080/13543784.2017.1373088
Relamorelin Preparation Products And Raw materials
Raw materials
Preparation Products
Relamorelin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4578 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4372 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| Binhai gill polypeptide co. LTD | 021-61263389 13524856427 | Joetang@glschina.com | China | 9927 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Wuxi Helen Biotechnology Co., Ltd., | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 14072 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7446 | 58 |
View Latest Price from Relamorelin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Relamorelin
661472-41-9
|
$497.00-1550.00 | 99.26% | 10g | TargetMol Chemicals Inc. |
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- Relamorelin
661472-41-9
- $497.00-1550.00
- 99.26%
- TargetMol Chemicals Inc.
