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ChemicalBook >> CAS DataBase List >>[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2)

[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2)

[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) Structure
[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) structure
CAS No.
5352-53-4
Chemical Name:
[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2)
Synonyms
BPH-1358 HCl;BPH-1358;Bacterial,inhibit,Inhibitor,NSC 50460,NSC-50460,BPH-1358,BPH 1358,BPH1358;N4,N4'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)-[1,1'-biphenyl]-4,4'-dicarboxamide dihydrochloride;[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2)
CBNumber:
CB73233567
Molecular Formula:
C32H29ClN6O2
Molecular Weight:
565.07
MDL Number:
MFCD32263017
MOL File:
5352-53-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) Properties

Melting point 330 °C
storage temp. -20°C
solubility DMF: insol,DMSO: 1 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
form A solid
color White to off-white

[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 37402 BPH-1358 ≥95% 5352-53-4 5mg $87 2026-04-30 Buy
Cayman Chemical 37402 BPH-1358 ≥95% 5352-53-4 10mg $164 2026-04-30 Buy
Cayman Chemical 37402 BPH-1358 ≥95% 5352-53-4 25mg $390 2026-04-30 Buy
Cayman Chemical 37402 BPH-1358 ≥95% 5352-53-4 50mg $736 2026-04-30 Buy
Biosynth FAA35253 BPH-1358 5352-53-4 100mg $789 2026-06-04 Buy
Product number Packaging Price Buy
37402 5mg $87 Buy
37402 10mg $164 Buy
37402 25mg $390 Buy
37402 50mg $736 Buy
FAA35253 100mg $789 Buy

[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) Chemical Properties, Uses, Production

Uses

BPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively, and is active against S. aureus in vitro (MIC ~250 ng/mL)[1][2].

in vivo

BPH-1358 is active against S. aureus in vivo (20/20 mice survived in an i.p. infection model with a MRSA strain)[1].

References

[1] Zhu W, et al. Antibacterial drug leads: DNA and enzyme multitargeting. J Med Chem. 2015 Feb 12;58(3):1215-27. DOI:10.1021/jm501449u
[2] Liu YL, et al. Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries. ACS Med Chem Lett. 2015 Jan 29;6(3):349-54. DOI:10.1021/ml500528x

[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) Preparation Products And Raw materials

Raw materials

Preparation Products

[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) Suppliers

Global Suppliers ( 22)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
DC Chemicals 021-58447131 13564518121 doncunbiosci@gmail.com China 618 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4999 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Taizhou GreenChem Pharma-Tech Co.,Ltd 15366892466 greenchem@tzglmk.com China 1095 58
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9185 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai SuperLan Chemcial Technique Centre 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
DC Chemicals 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Taizhou GreenChem Pharma-Tech Co.,Ltd 58
Beijing Boorsen Biotechnology Co., Ltd 58

View Latest Price from [1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BPH-1358 pictures 2026-07-15 BPH-1358
5352-53-4
 $30.00-123.00 99.74% 10g TargetMol Chemicals Inc.
BPH-1358 pictures 2026-07-15 BPH-1358
5352-53-4
 $30.00-123.00 99.74% 10g TargetMol Chemicals Inc.
  • BPH-1358 pictures
  • BPH-1358
    5352-53-4
  • $30.00-123.00
  • 99.74%
  • TargetMol Chemicals Inc.
  • BPH-1358 pictures
  • BPH-1358
    5352-53-4
  • $30.00-123.00
  • 99.74%
  • TargetMol Chemicals Inc.

[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) Spectrum

[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2)(5352-53-4)1HNMR

5352-53-4 ([1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2)) Related Search:

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[1,1'-Biphenyl]-4,4'-dicarboxamide,N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-, hydrochloride (1:2) BPH-1358 Bacterial,inhibit,Inhibitor,NSC 50460,NSC-50460,BPH-1358,BPH 1358,BPH1358 N4,N4'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)-[1,1'-biphenyl]-4,4'-dicarboxamide dihydrochloride BPH-1358 HCl 5352-53-4 C32H28N6O22ClH