3-CARENE
- CAS No.
- 13466-78-9
- Chemical Name:
- 3-CARENE
- Synonyms
- carene;DELTA-3-CARENE;Car-3-ene;3,7,7-TRIMETHYLBICYCLO[4.1.0]HEPT-3-ENE;D-CARENE;delta-3-CARENE, NATURAL;3-Karen;3-CARENE;3-CARVENE;FEMA 3821
- CBNumber:
- CB7349182
- Molecular Formula:
- C10H16
- Molecular Weight:
- 136.23
- MDL Number:
- MFCD00001315
- MOL File:
- 13466-78-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Carene ≥90% | W382108 | 1 each | $63.5 |
| 3-Carene 90% | 115576 | 25ml | $55.1 |
| 3-Carene 90% | 115576 | 1l | $164 |
| 3-Carene ≥90% | W382108 | 1 unit | $54.11 |
| 3-Carene ≥90% | W382108 | 1 unit | $54.11 |
| More product size | |||
| Melting point | 25°C |
|---|---|
| Boiling point | 168-169 °C/705 mmHg (lit.) |
| Density | 0.857 g/mL at 25 °C (lit.) |
| FEMA | 3821 | DELTA-3-CARENE |
| FLAVIS Number | 01.029 | delta-3-Carene |
| refractive index |
n |
| Flash point | 115 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform: Soluble; Methanol: Soluble |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Odor | at 100.00 %. citrus terpenic herbal pine solvent resinous phenolic cypress medicinal woody |
| Odor Type | citrus |
| optical activity | [α]20/D +15°, neat |
| biological source | synthetic |
| JECFA Number | 1342 |
| Merck | 1836 |
| Henry's Law Constant | 1.6×10-4 mol/(m3Pa) at 25℃, Falk et al. (1990) |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents. |
| Major Application | flavors and fragrances |
| Cosmetics Ingredients Functions | PERFUMING |
| InChI | 1S/C10H16/c1-7-4-5-8-9(6-7)10(8,2)3/h4,8-9H,5-6H2,1-3H3 |
| InChIKey | BQOFWKZOCNGFEC-UHFFFAOYSA-N |
| SMILES | CC1=CCC2C(C1)C2(C)C |
| LogP | 4.38 |
| Substances Added to Food (formerly EAFUS) | 3-CARENE |
| EWG's Food Scores | 2-5 |
| FDA UNII | H2M15SNR6N |
| EPA Substance Registry System | 3-Carene (13466-78-9) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H304-H315-H317-H412 | |||||||||
| Precautionary statements | P210-P273-P280-P301+P310-P303+P361+P353-P331 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,N,Xn | |||||||||
| Risk Statements | 10-43-50/53-65-38-52/53 | |||||||||
| Safety Statements | 16-26-36/37-60-61-62-37-24 | |||||||||
| RIDADR | UN 2319 3/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | FH8400000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3.2 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29021990 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Aquatic Chronic 3 Asp. Tox. 1 Flam. Liq. 3 Skin Irrit. 2 Skin Sens. 1 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
3-CARENE price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | W382108 | 3-Carene ≥90% | 13466-78-9 | 1 each | $63.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 115576 | 3-Carene 90% | 13466-78-9 | 25ml | $55.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 115576 | 3-Carene 90% | 13466-78-9 | 1l | $164 | 2026-04-30 | Buy |
| Sigma-Aldrich | W382108 | 3-Carene ≥90% | 13466-78-9 | 1 unit | $54.11 | 2025-07-31 | Buy |
| Sigma-Aldrich | W382108 | 3-Carene ≥90% | 13466-78-9 | 1 unit | $54.11 | 2025-07-31 | Buy |
3-CARENE Chemical Properties,Uses,Production
Description
Hydroperoxides of Δ-3-carene are allergens contained in turpentine. Occupational exposure occurs in painters, varnishers, or in ceramic decoration. The percentage of Δ-3-Carene is higher in Indonesian turpentine than in Portugese.
Description
(±)-3-Carene is a bicyclic monoterpene found in a variety of plants, including Cannabis. It decreases phagocytosis by rat alveolar macrophages when used at a concentration of 0.5 μM and decreases their viability at a concentration of 5 μM. (±)-3-Carene increases the expression and activity of alkaline phosphatase in mouse osteoblastic MC3T3-E1 subclone 4 cells, indicating induction of osteoblastic differentiation. It also induces calcium formation and increases the expression of osteopontin and type I collagen, which are related to osteoblast mineralization. (±)-3-Carene induces bronchoconstriction in isolated guinea pig lungs when exposed at an air concentration of 3,000 mg/m3.
Chemical Properties
Clear, colorless liquid. Stable to approx- imately 250C, resinifies with oxygen. Insoluble in water; miscible with organic solutions. Com- bustible.
Chemical Properties
3-Carene has a sweet, pungent turpentine-like taste.
Occurrence
Reported present in basil oil, bell pepper, bilberry, black currant berry juice and buds, fennel oil, grapefruit juice, kumquat peel oil, lemon peel oil, lime peel oil (cold pressed and distilled), lovage seed, mandarin peel oil, orange juice, orange peel oil, orange (bitter) peel oil, tangerine peel oil and other natural products.
Uses
Solvent, intermediate. 3-Carene is a mutagenic compound that may be found in the fumes of heating freshly cut spruce and birch chips. 3-Carene is also found i many esential oils and it inhibits acetylcholinesterase activity.
Definition
A terpene hydrocarbon with both a 6-member and 3-member ring.
Preparation
Extracted from the pine tree oil.
Synthesis Reference(s)
Tetrahedron Letters, 25, p. 5255, 1984 DOI: 10.1016/S0040-4039(01)81577-X
General Description
Colorless liquid with a sweet, turpentine-like odor. Floats on water.
Reactivity Profile
3-CARENE may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release hydrogen gas. In the presence of various catalysts (such as acids) or initiators, may undergo exothermic addition polymerization reactions. Will attack some forms of plastics [USCG, 1999].
Health Hazard
Inhalation causes headache, confusion, respiratory distress. Ingestion irritates entire digestive system and may injure kidneys; if liquid enters lungs, it causes severe pneumonitis. Contact with eyes or skin causes irritation.
Contact allergens
Hydroperoxides of D-3-carene are allergens contained in turpentine. Occupational exposure occurs in painters, varnishers, or ceramic decoration. The percentage of D-3-carene is higher in Indonesian than in Portuguese turpentine.
Toxics Screening Level
It is recommended that the Initial Threshold Screening Level (ITSL) for turpentine, along with select monoterpenes (a-pinene, p-pinene, and A3-carene) be set at 1120 μg/m3 based on an 8-hour averaging time.
References
[1] HILLIG K W. A chemotaxonomic analysis of terpenoid variation in Cannabis[J]. Biochemical Systematics and Ecology, 2004, 32 10: Pages 875-891. DOI: 10.1016/j.bse.2004.04.004
[2] ANNE JOHANSSON Margot L. Effects of low concentrations of 3-carene on alveolar macrophages in vitro[J]. Toxicology, 1997, 120 2: Pages 99-104. DOI: 10.1016/s0300-483x(97)03641-x
[3] JONG-GEUN JEONG. Low concentration of 3-carene stimulates the differentiation of mouse osteoblastic MC3T3-E1 subclone 4 cells.[J]. Phytotherapy Research, 2008, 22 1: 18-22. DOI: 10.1002/ptr.2247
[4] L LSTBOM. Mechanisms of 3-carene-induced bronchoconstriction in the isolated guinea pig lung.[J]. Respiration, 1995, 62 3: 130-135. DOI: 10.1159/000196407
[5] LENA LSTBOM . Does airway responsiveness increase after skin sensitisation to 3-carene: a study in isolated guinea pig lungs[J]. Toxicology, 1998, 125 1: Pages 59-66. DOI: 10.1016/s0300-483x(97)00182-0
3-CARENE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 661 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 10000 | 58 |
| Chemsigma International Co., Ltd. | +86-2558742998 +86-19951791336 | info@chemsigma.com | China | 1806 | 58 |
View Lastest Price from 3-CARENE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-20 | 3-Carene
13466-78-9
|
US $30.00-68.00 / mg | 92.18% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-05-20 | 3-Carene
13466-78-9
|
US $30.00-68.00 / mg | 92.18% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-05-20 | 3-Carene
13466-78-9
|
US $30.00-68.00 / mg | 92.18% | 10g | TargetMol Chemicals Inc. |
