BWMISRWJRUSYEX-YOVIYTQZSA-N
- CAS No.
- 1310012-15-7
- Chemical Name:
- BWMISRWJRUSYEX-YOVIYTQZSA-N
- Synonyms
- Famotidine EP Impurity F-d4;BWMISRWJRUSYEX-YOVIYTQZSA-N;Terbinafine-d3HCl (N-methyl-d3);Terbinafine-D3 Hydrochloride (Standard);N-[-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-(methyl-d3)-1-naphthalenemethanamine,monohydrochloride
- CBNumber:
- CB73601878
- Molecular Formula:
- C21H26ClN
- Molecular Weight:
- 327.9
- MDL Number:
- MFCD19705110
- MOL File:
- 1310012-15-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
BWMISRWJRUSYEX-YOVIYTQZSA-N price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26392 | Terbinafine-d3 (hydrochloride) ≥99%deuteratedforms(d1-d3) | 1310012-15-7 | 500μg | $96 | 2026-04-30 | Buy |
| Cayman Chemical | 26392 | Terbinafine-d3 (hydrochloride) ≥99%deuteratedforms(d1-d3) | 1310012-15-7 | 1mg | $171 | 2026-04-30 | Buy |
| Cayman Chemical | 26392 | Terbinafine-d3 (hydrochloride) ≥99%deuteratedforms(d1-d3) | 1310012-15-7 | 5mg | $748 | 2026-04-30 | Buy |
| TRC | TRC-T107501-5MG | Terbinafine-d3 HCl (N-methyl-d3) | 1310012-15-7 | 5mg | $987 | 2026-06-03 | Buy |
| TRC | TRC-T107501-10MG | Terbinafine-d3 HCl (N-methyl-d3) | 1310012-15-7 | 10mg | $1667 | 2026-06-03 | Buy |
BWMISRWJRUSYEX-YOVIYTQZSA-N Chemical Properties, Uses, Production
Description
Terbinafine-d3 is intended for use as an internal standard for the quantification of terbinafine by GC- or LC-MS. Terbinafine is a broad-spectrum antifungal agent that has activity against T. rubrum, T. mentagrophytes, T. verrucosum, E. floccosum, M. canis, A. fumigatus, and S. schenckii (MIC50s = 0.003-0.8 μg/ml). It selectively inhibits C. albicans squalene epoxidase over rat liver epoxidase (IC50s = 0.03 and 77 μM, respectively). Terbinafine (90-120 μM) induces cell cycle arrest at the G0/G1 phase in COLO 205 tumor cells and human umbilical vein endothelial cells (HUVECs). Formulations containing terbinafine have been used in the treatment of nail and skin fungal infections.
Uses
Terbinafine-d3 HCl (N-methyl-d3) (CAS# 1310012-15-7) is a useful isotopically labeled research compound.
References
[1] G PETRANYI H M J G Meingassner. Antifungal activity of the allylamine derivative terbinafine in vitro.[J]. Antimicrobial Agents and Chemotherapy, 1987, 31 9: 1365-1368. DOI: 10.1128/aac.31.9.1365
[2] N S RYDER M C D. Inhibition of squalene epoxidase by allylamine antimycotic compounds. A comparative study of the fungal and mammalian enzymes.[J]. Biochemical Journal, 1985, 230 3: 765-770. DOI: 10.1042/bj2300765
[3] WEN-SEN LEE. In vitro and in vivo studies of the anticancer action of terbinafine in human cancer cell lines: G0/G1 p53-associated cell cycle arrest[J]. International Journal of Cancer, 2003, 106 1: 125-137. DOI: 10.1002/ijc.11194
[4] PEI-YIN HO. Inhibition of human vascular endothelial cells proliferation by terbinafine[J]. International Journal of Cancer, 2004, 111 1: 51-59. DOI: 10.1002/ijc.20039
BWMISRWJRUSYEX-YOVIYTQZSA-N Preparation Products And Raw materials
Raw materials
Preparation Products
BWMISRWJRUSYEX-YOVIYTQZSA-N Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 | sinostandards@163.com | China | 4979 | 58 |
| Yancheng Tongming Biotechnology Co., Ltd. | 15195160625 | 2863565288@qq.com | China | 5178 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 | offer.de@lgcgroup.com | China | 19036 | 58 |
| CHINA ISOTOPE CO., LIMITED | 02151600108 13062666369 | info@isotopechem.com | China | 4721 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016; 18162595016 | 3287908757@qq.com | China | 9111 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12577 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
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