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Tiludronic acid

CAS No.
89987-06-4
Chemical Name:
Tiludronic acid
Synonyms
ACPMD;C08141;ME-3737;C1-TMBP;Tiludronic;TILUDRONIC ACID;Tilundronic Acid;Tiludronic acid disodium;Tiludronate disodium salt hydrate;(4-Chlorophenylthio)methylenediphosphonic acid
CBNumber:
CB7374025
Molecular Formula:
C7H9ClO6P2S
Molecular Weight:
318.61
MDL Number:
MFCD00867070
MOL File:
89987-06-4.mol
MSDS File:
SDS
Last updated:2026-01-13 11:25:35
Product description Number Pack Size Price
Tiludronate disodium salt hydrate ≥98% (HPLC) T4580 10mg $97.9
Tiludronate disodium salt hydrate ≥98% (HPLC) T4580 50mg $369
Tiludronic acid FT30708 10mg $324.5
Tiludronic acid FT30708 25mg $649
Tiludronic acid FT30708 50mg $973.5

Tiludronic acid Properties

Melting point 174-177 °C
Boiling point 600.7±65.0 °C(Predicted)
Density 1.82±0.1 g/cm3(Predicted)
storage temp. room temp
solubility H2O: >10mg/mL, clear
pka pK1 10.85; pK2 6.90; pK3 2.95; pK4 1.30(at 25℃)
form powder
color white to off-white
Water Solubility H2O: >10mg/mL, clear
InChI 1S/C7H9ClO6P2S.2Na.H2O/c8-5-1-3-6(4-2-5)17-7(15(9,10)11)16(12,13)14;;;/h1-4,7H,(H2,9,10,11)(H2,12,13,14);;;1H2/q;2*+1;/p-2
InChIKey SZVJRJRMQCKFON-UHFFFAOYSA-L
SMILES O.[Na+].[Na+].OP([O-])(=O)C(Sc1ccc(Cl)cc1)P(O)([O-])=O
FDA UNII 6PNS59HP4Y
ATC code M05BA05
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  3
Storage Class 11 - Combustible Solids

Tiludronic acid price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T4580 Tiludronate disodium salt hydrate ≥98% (HPLC) 89987-06-4 10mg $97.9 2026-04-30 Buy
Sigma-Aldrich T4580 Tiludronate disodium salt hydrate ≥98% (HPLC) 89987-06-4 50mg $369 2026-04-30 Buy
Biosynth FT30708 Tiludronic acid 89987-06-4 10mg $324.5 2026-06-04 Buy
Biosynth FT30708 Tiludronic acid 89987-06-4 25mg $649 2026-06-04 Buy
Biosynth FT30708 Tiludronic acid 89987-06-4 50mg $973.5 2026-06-04 Buy
Product number Packaging Price Buy
T4580 10mg $97.9 Buy
T4580 50mg $369 Buy
FT30708 10mg $324.5 Buy
FT30708 25mg $649 Buy
FT30708 50mg $973.5 Buy

Tiludronic acid Chemical Properties,Uses,Production

Chemical Properties

pKl 10.85; pK2 6.90; pK3 2.95; pKa 41.30. Tiludronic Acid Di-tert-butylamine Salt: melting point 253°C (decomposition).

Definition

ChEBI: Tiludronic acid is an organochlorine compound.

Biological Activity

Tiludronate is a bisphosphonate bone resorption inhibitor. Tiludronate inhibits protein-tyrosine-phosphatase, leading to detachment of osteoclasts from the bone surface. It also inhibits the osteoclastic proton pump and is used to tre at Pagetμs disease.

Veterinary Drugs and Treatments

Tiludronate disodium (tiludronic acid) is a bisphosphonate bone resorption inhibitor that is available in some countries for the intravenous treatment of navicular disease in horses. Treatment earlier in the course of the disease apparently results in greater efficacy.
For humans, there is an orally administered FDA-approved product for treating Paget’s disease (osteitis deformans).

Tiludronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Tiludronic acid Suppliers

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365 mina@chuanghaibio.com China 18126 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58
AFINE CHEMICALS LIMITED
+86-571-85134551 info@afinechem.com China 15083 58
Sinoway Industrial co., ltd.
+86-0592-5800732 +86-13806035118 xie@china-sinoway.com China 1369 58
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2123 70
Zhengzhou Gecko Scientific Inc. 0371-63336364 17344886665 209932355@qq.com China 522 55
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2317 55
Henan qinpeng technology co., ltd 微信:18839185240; 15737400781 2148319152@qq.com China 518 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 13675144456 sean.lv@synzest.com China 11438 58
Merck KGaA -- ordercn@merckgroup.com China 6394 58

View Lastest Price from Tiludronic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tiludronic Acid pictures 2026-06-22 Tiludronic Acid
89987-06-4
1kg 98% 20tons Sinoway Industrial co., ltd.
Tiludronic acid pictures 2025-06-27 Tiludronic acid
89987-06-4
1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
[[(4-Chlorophenyl)thio]methylene]bisphosphonic acid ACPMD C1-TMBP ME-3737 Tiludronate disodium salt hydrate Tiludronic acid disodium Tilundronic Acid TILUDRONIC ACID C08141 [[(4-Chlorophenyl)thio]methylene]bisphosphonic acid disodium salt hydrate Tiludronic (4-Chlorophenylthio)methylenediphosphonic acid Phosphonic acid, P,P'-[[(4-chlorophenyl)thio]methylene]bis- 89987-06-4 C7H9ClO6P2S API