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(S)-(-)-3-Cyclohexenecarboxylic acid

(S)-(-)-3-Cyclohexenecarboxylic acid Structure
(S)-(-)-3-Cyclohexenecarboxylic acid structure
CAS No.
5708-19-0
Chemical Name:
(S)-(-)-3-Cyclohexenecarboxylic acid
Synonyms
(S)-cyclohex-3-ene-1-carboxylic acid;(S)-3-Cyclohexene-1-carboxylic Acid;(S)-Cyclohex-3-enecarboxylic acid;(1S)-cyclohex-3-ene-1-carboxylic acid;(S)-(-)-3-CYCLOHEXENEC;(S)-(-)-3-CYCLOHEXENECARBOXYLICA;(1S)-3-cyclohexenecarboxylic acid;(S)-(-)-3-cyclohexencarboxylic acid;(S)-(-)-3-Cyclohexenecaboxylic acid;(1S)-cyclohex-3-ene-1-carboxylicaci
CBNumber:
CB7374252
Molecular Formula:
C7H10O2
Molecular Weight:
126.15
MDL Number:
MFCD08275437
MOL File:
5708-19-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:55
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(S)-(-)-3-Cyclohexenecarboxylic acid Properties

Melting point 19°C(lit.)
Boiling point 118°C/6mmHg(lit.)
Density 1.126±0.06 g/cm3(Predicted)
refractive index 1.4780 to 1.4820
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form clear liquid
pka 4.67±0.20(Predicted)
color Colorless to Almost colorless
InChI InChI=1S/C7H10O2/c8-7(9)6-4-2-1-3-5-6/h1-2,6H,3-5H2,(H,8,9)/t6-/m1/s1
InChIKey VUSWCWPCANWBFG-ZCFIWIBFSA-N
SMILES [C@H]1(C(O)=O)CCC=CC1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P305+P351+P338-P310
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8 / PGIII
HazardClass  8
PackingGroup  III
HS Code  2916200090
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
3 0

(S)-(-)-3-Cyclohexenecarboxylic acid price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C3236 (S)-(-)-3-Cyclohexene-1-carboxylic Acid >98.0%(GC)(T) 5708-19-0 1g $45 2026-04-30 Buy
Biosynth FC137309 (S)-(-)-3-Cyclohexene-1-carboxylic acid 5708-19-0 50g $900 2026-06-04 Buy
Biosynth FC137309 (S)-(-)-3-Cyclohexene-1-carboxylic acid 5708-19-0 500g $900 2026-06-04 Buy
Biosynth FC137309 (S)-(-)-3-Cyclohexene-1-carboxylic acid 5708-19-0 25g $900 2026-06-04 Buy
Biosynth FC137309 (S)-(-)-3-Cyclohexene-1-carboxylic acid 5708-19-0 250g $900 2026-06-04 Buy
Product number Packaging Price Buy
C3236 1g $45 Buy
FC137309 50g $900 Buy
FC137309 500g $900 Buy
FC137309 25g $900 Buy
FC137309 250g $900 Buy

(S)-(-)-3-Cyclohexenecarboxylic acid Chemical Properties, Uses, Production

Uses

(S)-(-)-3-CYCLOHEXENECARBOXYLIC ACID can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Uses

(S)-3-Cyclohexene-1-carboxylic Acid has been used as a reactant for the preparation of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonyl]amino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride, a potent and orally active direct inhibitor of factor Xa.

Synthesis

54.94 g of cyclohex-3-ene-1(S)-carboxylic acid (R)-(+)-methylbenzylamine salt and 18.2 volumes of H2O were charged to a flask at 20-25°C and stirred. To the mixture obtained further 6.7 volumes of H2O and 10 volumes of EtOAc were added. The mixture obtained was stirred for 15 min, the phases were separated and the organic layer was discarded. The aqueous layer was treated with 10 volumes of MTBE and 2.5 equivalents of 6M HCI were added slowly. The mixture obtained was stirred and two layers were formed, separated and the aqueous layer was extracted with MTBE. The organic layers obtained were combined and washed with aqueous, 30percent NaCl solution. The organic phase obtained was dried over Na2S04, filtered, and from the filtrate obtained solvent was removed in vacuo. Cyclohex-3-ene-1(S)-carboxylic acid in the form of a clear oil was obtained. Yield: 26.13 g (93.3percent of theory).

References

[1] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 3, p. 1193 - 1206
[2] Patent: EP2390245, 2011, A1. Location in patent: Page/Page column 15
[3] Patent: EP2399904, 2011, A1. Location in patent: Page/Page column 25
[4] Patent: EP1577301, 2005, A1. Location in patent: Page/Page column 191
[5] Patent: EP1405852, 2004, A1. Location in patent: Page 175

(S)-(-)-3-Cyclohexenecarboxylic acid Preparation Products And Raw materials

Raw materials

3-Cyclohexene-1-carboxylic acid, (1S)-, compd. with (αR)-α-methylbenzenemethanamine (1:1) 3-Cyclohexenecarboxylic acid 3-Cyclohexene-1-carboxylic acid methyl ester tert-Butyl methyl ether Water
Hydrochloric acid

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Preparation Products

Edoxaban Impurity 16 (1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one

(S)-(-)-3-Cyclohexenecarboxylic acid Suppliers

Global Suppliers ( 316)
Supplier Tel Email Country ProdList Advantage
Jinan Dexinjia Bio&Tech Co., Ltd 0531-82375880 15098789112 3845379039@qq.com China 1458 58
Chengdu Feibai Pharmaceutical Co., Ltd. 028-84641798 18782128315 3302391190@qq.com China 6141 55
Shanghai jing Hao pharmaceutical technology co., LTD 021-68900963 15618693615 sales@jinghaopharma.com China 300 58
Shandong Hongyuan Chemical Technology Co., LTD 13561560789 xinxiaoxiao2008@126.com China 1005 58
Jinan Kabotang Biological Technology Co.,Ltd. 0531-61320525 15866703830 figo.gao@foxmail.com China 7601 58
Hangzhou Yanding Biomedical Technology Co., Ltd. 18989469219 56560759@qq.com China 395 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Supplier Advantage
Jinan Dexinjia Bio&Tech Co., Ltd 58
Chengdu Feibai Pharmaceutical Co., Ltd. 55
Shanghai jing Hao pharmaceutical technology co., LTD 58
Shandong Hongyuan Chemical Technology Co., LTD 58
Jinan Kabotang Biological Technology Co.,Ltd. 58
Hangzhou Yanding Biomedical Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
TCI (Shanghai) Development Co., Ltd. 81
Ark Pharm, Inc. 56
Energy Chemical 61

View Latest Price from (S)-(-)-3-Cyclohexenecarboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(-)-3-CYCLOHEXENECARBOXYLIC ACID pictures 2026-09-02 (S)-(-)-3-CYCLOHEXENECARBOXYLIC ACID
5708-19-0
 $5.00 1KG 99% Henan Fengda Chemical Co., Ltd
(S)-(-)-3-Cyclohexenecarboxylic acid pictures 2025-04-04 (S)-(-)-3-Cyclohexenecarboxylic acid
5708-19-0
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
(S)-(-)-3-CYCLOHEXENECARBOXYLIC ACID pictures 2025-03-21 (S)-(-)-3-CYCLOHEXENECARBOXYLIC ACID
5708-19-0
 $1.00 1KG 98% 1000KGS Zhengzhou Anbu Chem Co.,Ltd

(S)-(-)-3-Cyclohexenecarboxylic acid Spectrum

(S)-(-)-3-CYCLOHEXENECARBOXYLIC ACID(5708-19-0)1HNMR

5708-19-0 ((S)-(-)-3-Cyclohexenecarboxylic acid) Related Search:

Cyclohexene 3-Cyclohexenecarboxylic acid (R)-(+)-3-Cyclohexenecarboxylic acid 3-Cyclohexene-1-methanol 3-Cyclohexene-1-carboxylic acid methyl ester
3-Cyclohexene-1-carboxylicacid,methylester,(1S)-(9CI)

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(S)-(?)-1,2,3,6-Tetrahydrobenzoic acid (1S)-CYCLOHEX-3-ENE-1-CARBOXYLIC ACID(1S)-CYCLOHEX-3-ENE-1-CARBOXYLIC ACID (1S)-3-Cyclohexene-1-carboxylic acid (S)-(-)-3-Cyclohexene-1-carboxylic Acid Chemicalbook(S)-3-Cyclohexene-1-carboxylicAcid (1S) -3- cyclohexene-1-carboxylate acid (S)-(-)-3-Cyclohexenecaboxylic acid 3-Cyclohexene-1-carboxylic acid, (1S)- (S)-(-)-3-CYCLOHEXENECARBOXYLIC ACID ISO 9001：2015 REACH (S)-(-)-3-CYCLOHEXENEC (S)-(-)-3-cyclohexencarboxylic acid (1S)-cyclohex-3-ene-1-carboxylicaci (S)-(-)-3-CYCLOHEXENECARBOXYLICA (S) - (-) -3-cyclohexeneformic acid (1S)-3-cyclohexenecarboxylic acid (1S)-cyclohex-3-ene-1-carboxylic acid (S)-Cyclohex-3-enecarboxylic acid (S)-3-Cyclohexene-1-carboxylic Acid (S)-cyclohex-3-ene-1-carboxylic acid (S)-(-)-3-Cyclohexenecarboxylic acid 5708-19-0 Edoxaban