REC IL-1RA (HUMAN)
- CAS No.
- Chemical Name:
- REC IL-1RA (HUMAN)
- Synonyms
- HUMAN IL-1RA;IL-1RA, HUMAN;REC IL-1RA (HUMAN);IL-1RA, ICIL-1RA, IRAP, IL-1RN;Mini Sample Mouse IL-1ra/IL-1F3;INTERLEUKIN 1 RECEPTOR ANTAGONIST;REC INTERLEUKIN-1 RECEPTOR ANTAGONIST (HUMAN);Mouse Interleukin 1 receptor antagonist elisa kit
- CBNumber:
- CB7401002
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00241901
- MOL File:
- Mol file
REC IL-1RA (HUMAN) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3084 | IL-1Ra human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 100μG | $395 | 2026-04-30 | Buy | |
| Usbiological | 320856 | Interleukin-1 Receptor antagonist PurifiedbyProteinGaffinitychromatography. | 50ug | $509 | 2026-06-03 | Buy | |
| Usbiological | 320856 | Interleukin-1 Receptor antagonist PurifiedbyProteinGaffinitychromatography. | 100ug | $708 | 2026-06-03 | Buy | |
| Usbiological | 320784 | Interleukin 1 Receptor antagonist Purifiedbyimmunoaffinitychromatography. | 100ul | $885 | 2026-06-03 | Buy | |
| Usbiological | I7663-25L | Interleukin 1 Receptor Antagonist | 20ug | $297 | 2021-12-16 | Buy |
REC IL-1RA (HUMAN) Chemical Properties, Uses, Production
Uses
IL-1Ra human has been used as an IL1 antagonist to block the signaling from the IL1 receptor and verify th at IL1 signaling is responsible for invasiveness in CD133-expressing cells. It has also been used as a control in sandwich enzyme-linked immunosorbent assay (ELISA) to measure protein levels.
General Description
The gene IL-1RA (interleukin-1 receptor antagonist) is mapped to human chromosome 2q. It belongs to the IL-1 (interleukin 1) family of proteins. The encoded protein has a TIR (Toll/IL-1 receptor) domain. IL-1RA is produced by corneal epithelial cells, monocytes, neutrophils, macrophages and fibroblasts. It is a naturally occurring inflammatory inhibitor protein. Recombinant human IL-1RA is a 17.2kDa protein consisting of 153 amino acid residues.
Biochem/physiol Actions
Interleukin-1 receptor antagonist (IL-1RA) inhibits the activity of IL-1α (interleukin 1 α) and IL-1β (interleukin 1 β) by competitively blocking binding to their type I and type II receptors. Therapeutically, IL-1RA may help in the treatment of sepsis, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease. Low production of IL-1RA is observed in HIV-1 (human immunodeficiency virus 1)-infected dendritic cells.
Description
IL1ra Human Recombinant produced in E.Coli is a non-glycosylated, N-terminal methionyl form of the human naturally-occurring polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.
The IL1ra is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
REC IL-1RA (HUMAN) Preparation Products And Raw materials
Raw materials
Preparation Products
REC IL-1RA (HUMAN) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Shanghai fantai biology science and technology co., ltd | 15601885736 | 2114786541@qq.com | China | 206 | 58 |
| Shanghai Yingxin Laboratory Equipment Co., Ltd. | 021-59178156 17002132182 | 3146474380@qq.com | China | 9997 | 58 |
| Shanghai Guchen Biotechnology Co., LTD | 021-34675735 19147740836 | 1986399151@qq.com | China | 9839 | 58 |
| Shanghai Jinshi Biochemical Technology Co., Ltd | 18601717983 18601717983 | 291017736@qq.com | China | 499 | 58 |
| Elabscience | 15608650971 | 1092989564@qq.com | China | 2895 | 58 |
