8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
- CAS No.
- 102146-07-6
- Chemical Name:
- 8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE
- Synonyms
- DPCPX;1,3-Dpcpx;PD 116,948;8-CYCLOPENTYL-1;PD-116948(DPCPX);DPCPX, PD 116,948;3-DIPROPYLXANTHINE;DPCPX, A1 antagonist;DPCPX, 10 mM in DMSO;Levodropropizine Impurity 15
- CBNumber:
- CB7472080
- Molecular Formula:
- C16H24N4O2
- Molecular Weight:
- 304.39
- MDL Number:
- MFCD00055117
- MOL File:
- 102146-07-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 8-Cyclopentyl-1,3-dipropylxanthine solid | C101 | 25mg | $106 |
| 8-Cyclopentyl-1,3-dipropylxanthine solid | C101 | 100mg | $221 |
| DPCPX ≥98% | 21972 | 10mg | $33 |
| DPCPX ≥98% | 21972 | 25mg | $79 |
| DPCPX ≥98% | 21972 | 50mg | $124 |
| Melting point | 178°C |
|---|---|
| Boiling point | 535.1±42.0 °C(Predicted) |
| Density | 1.195±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | DMSO: >10 mg/mL |
| form | solid |
| pka | 9.01±0.70(Predicted) |
| color | white |
| Stability | Store tightly sealed at RT; Solutions at 4°C for several days |
| InChI | 1S/C16H24N4O2/c1-3-9-19-14-12(15(21)20(10-4-2)16(19)22)17-13(18-14)11-7-5-6-8-11/h11H,3-10H2,1-2H3,(H,17,18) |
| InChIKey | FFBDFADSZUINTG-UHFFFAOYSA-N |
| SMILES | CCCN1C(=O)N(CCC)c2nc([nH]c2C1=O)C3CCCC3 |
| CAS DataBase Reference | 102146-07-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 9PTP4FOI9E |
| UNSPSC Code | 12352202 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C101 | 8-Cyclopentyl-1,3-dipropylxanthine solid | 102146-07-6 | 25mg | $106 | 2026-04-30 | Buy |
| Sigma-Aldrich | C101 | 8-Cyclopentyl-1,3-dipropylxanthine solid | 102146-07-6 | 100mg | $221 | 2026-04-30 | Buy |
| Cayman Chemical | 21972 | DPCPX ≥98% | 102146-07-6 | 10mg | $33 | 2026-04-30 | Buy |
| Cayman Chemical | 21972 | DPCPX ≥98% | 102146-07-6 | 25mg | $79 | 2026-04-30 | Buy |
| Cayman Chemical | 21972 | DPCPX ≥98% | 102146-07-6 | 50mg | $124 | 2026-04-30 | Buy |
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist
Uses
8-Cyclopentyl-1,3-dipropylxanthine has been used as an adenosine receptor (A1AR) antagonist in macrophages and human umbilical vein endothelial cells (HUVECs). It has also been used as A1AR antagonist in MCF-7 breast cancer cell line to test its anti-cancer effect.
Definition
ChEBI: An oxopurine that is 7H-xanthine substituted at positions 1 and 3 by propyl groups and at position 8 by a cyclohexyl group.
Biological Activity
Potent and selective A 1 adenosine receptor antagonist, both in vitro and in vivo . K i values are 3.9, 130, 50 and 4000 nM for human A 1 , A 2A , A 2B and A 3 receptors respectively.
Biochem/physiol Actions
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) is a selective A1adenosine receptor antagonist. DPCPX possesses anti-cancer functionality. It induces apoptosis in breast cancer cells and favors mRNA expression of caspases.
storage
Room temperature
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Preparation Products And Raw materials
Raw materials
Preparation Products
8-CYCLOPENTYL-1,3-DIPROPYLXANTHINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40048 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32288 | 55 |
| Nantong HI-FUTURE Biology Co., Ltd. | +86-18051384581 | sales@chemhifuture.com | China | 3123 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
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