Isocoptisine acetate
- CAS No.
- 30426-66-5
- Chemical Name:
- Isocoptisine acetate
- Synonyms
- Isocoptisine acetate;Pseudocoptisine acetate
- CBNumber:
- CB74806614
- Molecular Formula:
- C21H17NO6
- Molecular Weight:
- 379.37
- MDL Number:
- MFCD34469516
- MOL File:
- 30426-66-5.mol
| Product description | Number | Pack Size | Price |
| Pseudocoptisine(acetate) | CS-0100505 | 1mg | $724 |
| Isocoptisine acetate | orb594453 | 5mg | $1356.6 |
| Pseudocoptisine(acetate) | CS-0100505 | 5mg | $2171 |
| More product size | |||
Isocoptisine acetate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0100505 | Pseudocoptisine(acetate) | 30426-66-5 | 1mg | $724 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594453 | Isocoptisine acetate | 30426-66-5 | 5mg | $1356.6 | 2021-12-16 | Buy |
| ChemScene | CS-0100505 | Pseudocoptisine(acetate) | 30426-66-5 | 5mg | $2171 | 2021-12-16 | Buy |
Isocoptisine acetate Chemical Properties,Uses,Production
Uses
Pseudocoptisine (Isocoptisine) acetate is a quaternary alkaloid with benzylisoquinoline skeleton, was isolated from Corydalis Tuber. Pseudocoptisine acetate inhibits acetylcholinesterase (AChE) activity with an IC50 of 12.8 μM. Anti-inflammatory and anti-amnestic effects[1][2].
in vivo
The anti-amnesic activities of Pseudocoptisine in mice on the learning and memory impairments induced by scopolamine (1.0 mg/kg, i.p.) are examined. Pseudocoptisine (2.0 mg/kg, p.o.) significantly reverses cognitive impairments in mice by passive avoidance test[1].
References
[1] Hung TM, et al. Anti-amnestic activity of pseudocoptisine from Corydalis Tuber. Biol Pharm Bull. 2008;31(1):159-162. DOI:10.1248/bpb.31.159
[2] Yun KJ, et al. Quaternary alkaloid, pseudocoptisine isolated from tubers of Corydalis turtschaninovi inhibits LPS-induced nitric oxide, PGE(2), and pro-inflammatory cytokines production via the down-regulation of NF-kappaB in RAW 264.7 murine macrophage c DOI:10.1016/j.intimp.2009.08.001
Isocoptisine acetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Mensura Group Limited | 18780014153 | 1058503172@qq.com | China | 2900 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 18108052721 | 2850505130@qq.com | China | 5167 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
| Naturewill Biotechnology Co., Ltd. | 028-82632533 18113192475 | 3157321941@qq.com | China | 4993 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9835 | 58 |
