ChemicalBook >> CAS DataBase List >>2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

CAS No.
68682-01-9
Chemical Name:
2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
Synonyms
6PNG;(2R/S)-6-PNG;(2R/S)6PNG,(2R/S) 6 PNG;(2R/S)-6-PNG, 10 mM in DMSO;Naringenin 6-Prenyl Racemate;5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)chroman-4-one;2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-
CBNumber:
CB74902675
Molecular Formula:
C20H20O5
Molecular Weight:
340.37
MDL Number:
MFCD21364780
MOL File:
68682-01-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:36:03

2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one Properties

Melting point 212-214 °C(Solv: methanol (67-56-1))
Boiling point 604.2±55.0 °C(Predicted)
Density 1.314±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form A solid
pka 8.06±0.40(Predicted)
color White to off-white
Stability Light Sensitive
Major Application food and beverages
InChI 1S/C20H20O5/c1-11(2)3-8-14-15(22)9-18-19(20(14)24)16(23)10-17(25-18)12-4-6-13(21)7-5-12/h3-7,9,17,21-22,24H,8,10H2,1-2H3/t17-/m0/s1
InChIKey YHWNASRGLKJRJJ-KRWDZBQOSA-N
SMILES OC1=C(C(CC(C2=CC=C(O)C=C2)O3)=O)C3=CC(O)=C1CC=C(C)C
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P280-P301+P312+P330-P302+P352+P312-P304+P340+P312
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
NFPA 704
0
3 0

2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 75602 6-Prenylnaringenin analytical standard 68682-01-9 5MG $729 2022-05-15 Buy
Cayman Chemical 34499 (±)-6-Prenylnaringenin ≥95% 68682-01-9 1mg $85 2026-04-30 Buy
Cayman Chemical 34499 (±)-6-Prenylnaringenin ≥95% 68682-01-9 5mg $274 2026-04-30 Buy
TRC TRC-P712905-5MG 6-Prenyl-rac-naringenin 68682-01-9 5mg $384 2026-06-03 Buy
TRC TRC-P712905-50MG 6-Prenyl-rac-naringenin 68682-01-9 50mg $2084 2026-06-03 Buy
Product number Packaging Price Buy
75602 5MG $729 Buy
34499 1mg $85 Buy
34499 5mg $274 Buy
TRC-P712905-5MG 5mg $384 Buy
TRC-P712905-50MG 50mg $2084 Buy

2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one Chemical Properties, Uses, Production

Uses

6-Prenyl-rac-naringenin is a natural product isolated from Cudrania tricuspidata root which showed growth inhibition against Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae.

Definition

ChEBI: (S)-4',5,7-Trihydroxy-6-prenylflavanone is a member of flavanones.

in vivo

(2R/S)-6-PNG (6-Prenylnaringenin; 10-30 mg/kg; i.p.; single dose; 15 min before Na2S) significantly reduced the Na2S-induced nociceptive behavior and/or referred hyperalgesia in onscious mice with intracolonic (i.col.) administration of Na2S, an H2S donor[1].
(2R/S)-6-PNG (30 mg/kg; i.p.) prevents the increased number of phosphorylated ERK-positive cells following i.col. Na2S in laminae I-II, V-VI and X to which the primary afferent neurons project, and the Na2S-induced increase in the phosphorylated ERK-positive cell number[1].
(2R/S)-6-PNG (0.01-1 and 0.1-10 nmol/paw; intraplantar administration) restores the mechanical allodynia induced by partial sciatic nerve ligation (PSNL) and by i.p. administration of Oxaliplatin (OHP) a, respectively, in a dose-dependent manner[1].
(2R/S)-6-PNG (20-30 mg/kg; i.p.) significantly reverses the PSNL-induced allodynia. (2R/S)-6-PNG (10-20 mg/kg; i.p.) significantly reverses the OHP-induced allodynia (5 mg/kg; i.p.; single dose)[1].

IC 50

T-type calcium channel

2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one Suppliers

Global Suppliers ( 34)
Supplier Tel Email Country ProdList Advantage
Nanjing Spring & Autumn Biological Engineering Co., Ltd. 17388075642 13815430202 sale02@cqherb.com China 261 59
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 3982 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai Yihe Biological Technology Co., Ltd. 021-68882955 17721395025 2423903095@qq.com China 5000 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Chunchuang (Wuhan) Technology Co., Ltd 15727060112 yutianchun2007@126.com China 9867 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58

View Latest Price from 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(2R/S)-6-PNG pictures 2026-05-11 (2R/S)-6-PNG
68682-01-9
$95.00 98.00% 10g TargetMol Chemicals Inc.
2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one 6PNG (2R/S)-6-PNG Naringenin 6-Prenyl Racemate (2R/S)6PNG,(2R/S) 6 PNG 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten-1-yl)- (2R/S)-6-PNG, 10 mM in DMSO 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)chroman-4-one 68682-01-9