ChemicalBook >> CAS DataBase List >>9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid

9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid

CAS No.
24769-56-0
Chemical Name:
9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid
Synonyms
TETRANOR-PGEM;Tetranor-PGEM-13C6;prostaglandin E2-UM;TETRANOR PROSTAGLANDIN E METABOLITE;tetranor-PGEM Lipid Maps MS Standard;9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid;11alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoicacid;Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-ε,3-dioxo-, (1R,2R,5R)-
CBNumber:
CB7492637
Molecular Formula:
C16H24O7
Molecular Weight:
328.36
MDL Number:
MFCD00797649
MOL File:
24769-56-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:54:59

9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid Properties

Boiling point 622.2±50.0 °C(Predicted)
Density 1.266±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: Not Stable; PBS (pH 7.2): 1 mg/ml
form Liquid
pka 4.61±0.10(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 14840 tetranor-PGEM ≥98% 24769-56-0 25μg $147 2026-04-30 Buy
Cayman Chemical 14840 tetranor-PGEM ≥98% 24769-56-0 50μg $277 2026-04-30 Buy
Cayman Chemical 14840 tetranor-PGEM ≥98% 24769-56-0 100μg $522 2026-04-30 Buy
ChemScene CS-0064738 PGE-M 99.9% 24769-56-0 25μg(304.54μM*250μLinMethylacetate) $433 2026-06-04 Buy
TRC P294100 PGE-M 24769-56-0 25mg $16225 2021-12-16 Buy
Product number Packaging Price Buy
14840 25μg $147 Buy
14840 50μg $277 Buy
14840 100μg $522 Buy
CS-0064738 25μg(304.54μM*250μLinMethylacetate) $433 Buy
P294100 25mg $16225 Buy

9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid Chemical Properties, Uses, Production

Description

tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis. About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy males excrete 7-40 μg of tetranor-PGEM over a 24-hour period.

Uses

The major urinary metabolite of Prostaglandin E2 (P838610).

Definition

ChEBI: A prostanoid that is prostaglandin E2 in which the acyclic hydroxy group has been oxidised to the corresponding ketone, the methyl group has been oxidised to the corresponding carboxylic acid and the 6-carboxyhexenyl group has been oxidatively cleaved to a 2-carboxyethyl group. It is the major urinary metabolite of prostaglandin E2.

References

[1] JASON R. NEALE  Brian J D. Liquid chromatography–tandem mass spectrometric quantification of the dehydration product of tetranor PGE-M, the major urinary metabolite of prostaglandin E2 in human urine[J]. Journal of Chromatography B, 2008, 871 1: Pages 72-77. DOI: 10.1016/j.jchromb.2008.06.042
[2] YOSHIFUMI MORITA. Simultaneous analyses of urinary eicosanoids and related mediators identified tetranor-prostaglandin E metabolite as a novel biomarker of diabetic nephropathy.[J]. Journal of Lipid Research, 2021: 100120. DOI: 10.1016/j.jlr.2021.100120
[3] YONG CUI. Urinary prostaglandin E2 metabolite and breast cancer risk.[J]. ACS Applied Electronic Materials, 2014: 2866-2873. DOI: 10.1158/1055-9965.epi-14-0685

9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid Preparation Products And Raw materials

Raw materials

Preparation Products

9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid Suppliers

Global Suppliers ( 45)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 57336 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
BOC Sciences +1-631-485-4226 inquiry@bocsci.com United States 19935 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58

View Latest Price from 9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID pictures 2026-06-30 9,15-DIOXO-11ALPHA-HYDROXY-2,3,4,5-TETRANOR-PROSTAN-1,20-DIOIC ACID
24769-56-0
1KG 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
tetranor-PGEM pictures 2026-04-20 tetranor-PGEM
24769-56-0
$482.00 10g TargetMol Chemicals Inc.
11alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor-19-carboxyprostanoicacid TETRANOR PROSTAGLANDIN E METABOLITE TETRANOR-PGEM tetranor-PGEM Lipid Maps MS Standard prostaglandin E2-UM Cyclopentaneoctanoic acid, 2-(2-carboxyethyl)-5-hydroxy-ε,3-dioxo-, (1R,2R,5R)- Tetranor-PGEM-13C6 9,15-Dioxo-11alpha-hydroxy-2,3,4,5-tetranor-prostan-1,20-dioic acid 24769-56-0 Chiral Reagents Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals